| Comparison of ternary complexes of Pneumocystis carinii and wild-type human dihydrofolate reductase with coenzyme NADPH and a novel classical antitumor furo[2,3-d]pyrimidine antifolate. Cody V., Galitsky N., Luft J.R., Pangborn W., Gangjee A., Devraj R., Queener S.F., Blakley R.L.
Acta Crystallogr. D Biol. Crystallogr. 53:638-649(1997) · Mapped (1) |
| 5,10-Methylenetetrahydrofolic dehydrogenase from bakers' yeast. I. Partial purification and some properties. RAMASASTRI B.V., BLAKLEY R.L.
J. Biol. Chem. 237:1982-1988(1962) · Mapped (2) |
| 5,10-METHYLENETETRAHYDROFOLIC DEHYDROGENASE FROM BAKERS' YEAST. III. STEREOSPECIFICITY OF HYDROGEN TRANSFER IN THE REACTION CATALYZED BY THE ENZYME. RAMASASTRI B.V., BLAKLEY R.L.
J. Biol. Chem. 239:112-114(1964) · Mapped (2) |
| 5,10-METHYLENETETRAHYDROFOLIC DEHYDROGENASE FROM BAKERS' YEAST. II. USE IN ASSAY OF TETRAHYDROFOLIC ACID. RAMASASTRI B.V., BLAKLEY R.L.
J. Biol. Chem. 239:106-111(1964) · Mapped (2) |
| Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine. Cody V., Galitsky N., Luft J.R., Pangborn W., Blakley R.L., Gangjee A.
Anticancer Drug Des. 13:307-315(1998) · Mapped (1) |
| In vitro mutations in dihydrofolate reductase that confer resistance to methotrexate: potential for clinical application. Blakley R.L., Sorrentino B.P.
Hum. Mutat. 11:259-263(1998) · Mapped (2) |
| Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523. Cody V., Galitsky N., Luft J.R., Pangborn W., Blakley R.L., Gangjee A.
Biochemistry 36:13897-13903(1997) · UniProtKB (1) |
| Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers. Lewis W.S., Cody V., Galitsky N., Luft J.R., Pangborn W., Chunduru S.K., Spencer H.T., Appleman J.R., Blakley R.L.
J. Biol. Chem. 270:5057-5064(1995) · UniProtKB (1) |
| Structure of dihydrofolate reductase: primary sequence of the bovine liver enzyme. Lai P.-H., Pan Y.-C.E., Gleisner J.M., Peterson D.L., Williams K.R., Blakley R.L.
Biochemistry 21:3284-3294(1982) · UniProtKB (1) |
| The structure of the mutant dihydrofolate reductase from Streptococcus faecium. Amino acid sequence of peptide CNBr 7 and complete sequence of the protein. Peterson D.L., Gleisner J.M., Blakley R.L.
J. Biol. Chem. 250:4945-4954(1975) · UniProtKB (1) |
