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1 - 25 of 69 results for author:"Beyaert R." in Literature citations

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A20 inhibits LUBAC-mediated NF-kappaB activation by binding linear polyubiquitin chains via its zinc finger 7.

Verhelst K., Carpentier I., Kreike M., Meloni L., Verstrepen L., Kensche T., Dikic I., Beyaert R.

EMBO J. 31:3845-3855(2012) · Mapped (21)

The p110delta isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock.

Aksoy E., Taboubi S., Torres D., Delbauve S., Hachani A., Whitehead M.A., Pearce W.P., Berenjeno-Martin I., Nock G., Filloux A. et al.

Nat. Immunol. 13:1045-1054(2012) · Mapped (17)

A20 and CYLD do not share significant overlapping functions during B cell development and activation.

Chu Y., Soberon V., Glockner L., Beyaert R., Massoumi R., van Loo G., Krappmann D., Schmidt-Supprian M.

J. Immunol. 189:4437-4443(2012) · Mapped (30)

Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33.

Willart M.A., Deswarte K., Pouliot P., Braun H., Beyaert R., Lambrecht B.N., Hammad H.

J. Exp. Med. 209:1505-1517(2012) · Mapped (10)

A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection.

Maelfait J., Roose K., Bogaert P., Sze M., Saelens X., Pasparakis M., Carpentier I., van Loo G., Beyaert R.

PLoS Pathog. 8:e1002570-e1002570(2012) · Mapped (6)

Neu1 sialidase and matrix metalloproteinase-9 cross-talk is essential for Toll-like receptor activation and cellular signaling.

Abdulkhalek S., Amith S.R., Franchuk S.L., Jayanth P., Guo M., Finlay T., Gilmour A., Guzzo C., Gee K., Beyaert R. et al.

J. Biol. Chem. 286:36532-36549(2011) · Mapped (18)

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis.

Matmati M., Jacques P., Maelfait J., Verheugen E., Kool M., Sze M., Geboes L., Louagie E., Mc Guire C., Vereecke L. et al.

Nat. Genet. 43:908-912(2011) · Mapped (9)

Linear ubiquitination in NF-kappaB signaling and inflammation: What we do understand and what we do not.

Verhelst K., Verstrepen L., Carpentier I., Beyaert R.

Biochem. Pharmacol. 82:1057-1065(2011) · Mapped (3)

Genetic relationships between A20/TNFAIP3, chronic inflammation and autoimmune disease.

Vereecke L., Beyaert R., van Loo G.

Biochem. Soc. Trans. 39:1086-1091(2011) · Mapped (21)

The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity.

Kool M., van Loo G., Waelput W., De Prijck S., Muskens F., Sze M., van Praet J., Branco-Madeira F., Janssens S., Reizis B. et al.

Immunity 35:82-96(2011) · Mapped (8)

Keratinocyte-specific ablation of the NF-kappaB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis.

Lippens S., Lefebvre S., Gilbert B., Sze M., Devos M., Verhelst K., Vereecke L., Mc Guire C., Guerin C., Vandenabeele P. et al.

Cell Death Differ. 18:1845-1853(2011) · Mapped (6)

T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1.

Staal J., Driege Y., Bekaert T., Demeyer A., Muyllaert D., Van Damme P., Gevaert K., Beyaert R.

EMBO J. 30:1742-1752(2011) · Mapped (4)

B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice.

Chu Y., Vahl J.C., Kumar D., Heger K., Bertossi A., Wojtowicz E., Soberon V., Schenten D., Mack B., Reutelshofer M. et al.

Blood 117:2227-2236(2011) · Mapped (8)

Oligodendrocyte-specific FADD deletion protects mice from autoimmune-mediated demyelination.

Mc Guire C., Volckaert T., Wolke U., Sze M., de Rycke R., Waisman A., Prinz M., Beyaert R., Pasparakis M., van Loo G.

J. Immunol. 185:7646-7653(2010) · Mapped (8)

In macrophages, caspase-1 activation by SopE and the type III secretion system-1 of S. typhimurium can proceed in the absence of flagellin.

Hoffmann C., Galle M., Dilling S., Kappeli R., Muller A.J., Songhet P., Beyaert R., Hardt W.D.

PLoS ONE 5:e12477-e12477(2010) · Mapped (1)

Cleavage by MALT1 induces cytosolic release of A20.

Malinverni C., Unterreiner A., Staal J., Demeyer A., Galaup M., Luyten M., Beyaert R., Bornancin F.

Biochem. Biophys. Res. Commun. 400:543-547(2010) · UniProtKB (1) · Mapped (22)

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis.

Vereecke L., Sze M., Mc Guire C., Rogiers B., Chu Y., Schmidt-Supprian M., Pasparakis M., Beyaert R., van Loo G.

J. Exp. Med. 207:1513-1523(2010) · Mapped (26)

Endoplasmic reticulum chaperone gp96 is essential for infection with vesicular stomatitis virus.

Bloor S., Maelfait J., Krumbach R., Beyaert R., Randow F.

Proc. Natl. Acad. Sci. U.S.A. 107:6970-6975(2010) · Mapped (8)

Caspase-1 targets the TLR adaptor Mal at a crucial TIR-domain interaction site.

Ulrichts P., Bovijn C., Lievens S., Beyaert R., Tavernier J., Peelman F.

J. Cell. Sci. 123:256-265(2010) · Mapped (9)

Caspase-11 mediates ischemia-induced astrocyte death: involvement of endoplasmic reticulum stress and C/EBP homologous protein.

Fradejas N., Pastor M.D., Burgos M., Beyaert R., Tranque P., Calvo S.

J. Neurosci. Res. 88:1094-1105(2010) · Mapped (3)

The S. Typhimurium effector SopE induces caspase-1 activation in stromal cells to initiate gut inflammation.

Muller A.J., Hoffmann C., Galle M., Van Den Broeke A., Heikenwalder M., Falter L., Misselwitz B., Kremer M., Beyaert R., Hardt W.D.

Cell Host Microbe 6:125-136(2009) · Mapped (1)

The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology.

Vereecke L., Beyaert R., van Loo G.

Trends Immunol. 30:383-391(2009) · Mapped (21)

ABINs: A20 binding inhibitors of NF-kappa B and apoptosis signaling.

Verstrepen L., Carpentier I., Verhelst K., Beyaert R.

Biochem. Pharmacol. 78:105-114(2009) · Mapped (20)

Dependence of pathogen molecule-induced toll-like receptor activation and cell function on Neu1 sialidase.

Amith S.R., Jayanth P., Franchuk S., Siddiqui S., Seyrantepe V., Gee K., Basta S., Beyaert R., Pshezhetsky A.V., Szewczuk M.R.

Glycoconj. J. 26:1197-1212(2009) · Mapped (3)

Attenuated expression of A20 markedly increases the efficacy of double-stranded RNA-activated dendritic cells as an anti-cancer vaccine.

Breckpot K., Aerts-Toegaert C., Heirman C., Peeters U., Beyaert R., Aerts J.L., Thielemans K.

J. Immunol. 182:860-870(2009) · Mapped (21)

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