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1 - 25 of 119 results for author:"Beutler B." in Literature citations

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Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease.

Siggs O.M., Cruite J.T., Du X., Rutschmann S., Masliah E., Beutler B., Oldstone M.B.

Proc. Natl. Acad. Sci. U.S.A. 109:13733-13738(2012) · Mapped (5)

Yip1 domain family, member 6 (Yipf6) mutation induces spontaneous intestinal inflammation in mice.

Brandl K., Tomisato W., Li X., Neppl C., Pirie E., Falk W., Xia Y., Moresco E.M., Baccala R., Theofilopoulos A.N. et al.

Proc. Natl. Acad. Sci. U.S.A. 109:12650-12655(2012) · Mapped (3)

A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity.

Arnold C.N., Pirie E., Dosenovic P., McInerney G.M., Xia Y., Wang N., Li X., Siggs O.M., Karlsson Hedestam G.B., Beutler B.

Proc. Natl. Acad. Sci. U.S.A. 109:12286-12293(2012) · Mapped (82)

iRhom2 is required for the secretion of mouse TNFalpha.

Siggs O.M., Xiao N., Wang Y., Shi H., Tomisato W., Li X., Xia Y., Beutler B.

Blood 119:5769-5771(2012) · Mapped (6)

Hypopigmentation and maternal-zygotic embryonic lethality caused by a hypomorphic mbtps1 mutation in mice.

Rutschmann S., Crozat K., Li X., Du X., Hanselman J.C., Shigeoka A.A., Brandl K., Popkin D.L., McKay D.B., Xia Y. et al.

G3 (Bethesda) 2:499-504(2012) · Mapped (11)

Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses.

Narni-Mancinelli E., Jaeger B.N., Bernat C., Fenis A., Kung S., De Gassart A., Mahmood S., Gut M., Heath S.C., Estelle J. et al.

Science 335:344-348(2012) · Mapped (3)

ZBTB1 is a determinant of lymphoid development.

Siggs O.M., Li X., Xia Y., Beutler B.

J. Exp. Med. 209:19-27(2012) · Mapped (12)

Increased susceptibility to DNA virus infection in mice with a GCN2 mutation.

Won S., Eidenschenk C., Arnold C.N., Siggs O.M., Sun L., Brandl K., Mullen T.M., Nemerow G.R., Moresco E.M., Beutler B.

J. Virol. 86:1802-1808(2012) · Mapped (46)

Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet.

Krebs P., Fan W., Chen Y.H., Tobita K., Downes M.R., Wood M.R., Sun L., Li X., Xia Y., Ding N. et al.

Proc. Natl. Acad. Sci. U.S.A. 108:19678-19682(2011) · Mapped (1)

Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype.

Blasius A.L., Dubin A.E., Petrus M.J., Lim B.K., Narezkina A., Criado J.R., Wills D.N., Xia Y., Moresco E.M., Ehlers C. et al.

Proc. Natl. Acad. Sci. U.S.A. 108:19413-19418(2011) · Mapped (3)

Mutation of the gastric hydrogen-potassium ATPase alpha subunit causes iron-deficiency anemia in mice.

Krieg L., Milstein O., Krebs P., Xia Y., Beutler B., Du X.

Blood 118:6418-6425(2011) · Mapped (4)

The role of Vldlr in intraretinal angiogenesis in mice.

Xia C.H., Lu E., Liu H., Du X., Beutler B., Gong X.

Invest. Ophthalmol. Vis. Sci. 52:6572-6579(2011) · Mapped (8)

Toll-like receptors.

Moresco E.M., LaVine D., Beutler B.

Curr. Biol. 21:R488-93(2011) · Mapped (2)

ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections.

Eleftherianos I., Won S., Chtarbanova S., Squiban B., Ocorr K., Bodmer R., Beutler B., Hoffmann J.A., Imler J.L.

Proc. Natl. Acad. Sci. U.S.A. 108:12024-12029(2011) · Mapped (33)

Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses.

Zak D.E., Schmitz F., Gold E.S., Diercks A.H., Peschon J.J., Valvo J.S., Niemisto A., Podolsky I., Fallen S.G., Suen R. et al.

Proc. Natl. Acad. Sci. U.S.A. 108:11536-11541(2011) · Mapped (5)

Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice.

Krebs P., Crozat K., Popkin D., Oldstone M.B., Beutler B.

Blood 117:6582-6588(2011) · Mapped (32)

X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C.

Siggs O.M., Schnabl B., Webb B., Beutler B.

Proc. Natl. Acad. Sci. U.S.A. 108:7890-7895(2011) · Mapped (14)

The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow.

Siggs O.M., Arnold C.N., Huber C., Pirie E., Xia Y., Lin P., Nemazee D., Beutler B.

Nat. Immunol. 12:434-440(2011) · Mapped (42)

Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner.

Popkin D.L., Teijaro J.R., Sullivan B.M., Urata S., Rutschmann S., de la Torre J.C., Kunz S., Beutler B., Oldstone M.

Cell Host Microbe 9:212-222(2011) · Mapped (6)

A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding.

Iavarone C., Ramsauer K., Kubarenko A.V., Debasitis J.C., Leykin I., Weber A.N., Siggs O.M., Beutler B., Zhang P., Otten G. et al.

J. Immunol. 186:4213-4222(2011) · Mapped (5)

Impact of beta2 integrin deficiency on mouse natural killer cell development and function.

Crozat K., Eidenschenk C., Jaeger B.N., Krebs P., Guia S., Beutler B., Vivier E., Ugolini S.

Blood 117:2874-2882(2011) · Mapped (8)

Rapid identification of a disease allele in mouse through whole genome sequencing and bulk segregation analysis.

Arnold C.N., Xia Y., Lin P., Ross C., Schwander M., Smart N.G., Muller U., Beutler B.

Genetics 187:633-641(2011) · Mapped (3)

JNK1 controls mast cell degranulation and IL-1{beta} production in inflammatory arthritis.

Guma M., Kashiwakura J., Crain B., Kawakami Y., Beutler B., Firestein G.S., Kawakami T., Karin M., Corr M.

Proc. Natl. Acad. Sci. U.S.A. 107:22122-22127(2010) · Mapped (14)

Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells.

Blasius A.L., Arnold C.N., Georgel P., Rutschmann S., Xia Y., Lin P., Ross C., Li X., Smart N.G., Beutler B.

Proc. Natl. Acad. Sci. U.S.A. 107:19973-19978(2010) · Mapped (60)

MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands.

Brandl K., Sun L., Neppl C., Siggs O.M., Le Gall S.M., Tomisato W., Li X., Du X., Maennel D.N., Blobel C.P. et al.

Proc. Natl. Acad. Sci. U.S.A. 107:19967-19972(2010) · Mapped (32)

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