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A metabolomic and systems biology perspective on the brain of the fragile X syndrome mouse model.

Davidovic L., Navratil V., Bonaccorso C.M., Catania M.V., Bardoni B., Dumas M.E.

Genome Res. 21:2190-2202(2011) · Mapped (11)

Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability.

Melko M., Douguet D., Bensaid M., Zongaro S., Verheggen C., Gecz J., Bardoni B.

Hum. Mol. Genet. 20:1873-1885(2011) · Mapped (8)

A novel function for fragile X mental retardation protein in translational activation.

Bechara E.G., Didiot M.C., Melko M., Davidovic L., Bensaid M., Martin P., Castets M., Pognonec P., Khandjian E.W., Moine H. et al.

PLoS Biol. 7:e16-e16(2009) · Mapped (2)

FRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structure.

Bensaid M., Melko M., Bechara E.G., Davidovic L., Berretta A., Catania M.V., Gecz J., Lalli E., Bardoni B.

Nucleic Acids Res. 37:1269-1279(2009) · UniProtKB (2) · Mapped (2)

Alteration of expression of muscle specific isoforms of the fragile X related protein 1 (FXR1P) in facioscapulohumeral muscular dystrophy patients.

Davidovic L., Sacconi S., Bechara E.G., Delplace S., Allegra M., Desnuelle C., Bardoni B.

J. Med. Genet. 45:679-685(2008) · Mapped (6)

The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery.

Boulon S., Marmier-Gourrier N., Pradet-Balade B., Wurth L., Verheggen C., Jady B.E., Rothe B., Pescia C., Robert M.C., Kiss T. et al.

J. Cell Biol. 180:579-595(2008) · Mapped (4)

The fragile X mental retardation protein is a molecular adaptor between the neurospecific KIF3C kinesin and dendritic RNA granules.

Davidovic L., Jaglin X.H., Lepagnol-Bestel A.M., Tremblay S., Simonneau M., Bardoni B., Khandjian E.W.

Hum. Mol. Genet. 16:3047-3058(2007) · Mapped (30)

Fragile X related protein 1 isoforms differentially modulate the affinity of fragile X mental retardation protein for G-quartet RNA structure.

Bechara E., Davidovic L., Melko M., Bensaid M., Tremblay S., Grosgeorge J., Khandjian E.W., Lalli E., Bardoni B.

Nucleic Acids Res. 35:299-306(2007) · Mapped (2)

Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology.

Kim Y., Sung J.Y., Ceglia I., Lee K.W., Ahn J.H., Halford J.M., Kim A.M., Kwak S.P., Park J.B., Ho Ryu S. et al.

Nature 442:814-817(2006) · Mapped (1)

The nuclear microspherule protein 58 is a novel RNA-binding protein that interacts with fragile X mental retardation protein in polyribosomal mRNPs from neurons.

Davidovic L., Bechara E., Gravel M., Jaglin X.H., Tremblay S., Sik A., Bardoni B., Khandjian E.W.

Hum. Mol. Genet. 15:1525-1538(2006) · UniProtKB (1) · Mapped (2)

The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction.

Ramos A., Hollingworth D., Adinolfi S., Castets M., Kelly G., Frenkiel T.A., Bardoni B., Pastore A.

Structure 14:21-31(2006) · UniProtKB (1) · Mapped (7)

FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts.

Castets M., Schaeffer C., Bechara E., Schenck A., Khandjian E.W., Luche S., Moine H., Rabilloud T., Mandel J.L., Bardoni B.

Hum. Mol. Genet. 14:835-844(2005) · Mapped (5)

WAVE/SCAR, a multifunctional complex coordinating different aspects of neuronal connectivity.

Schenck A., Qurashi A., Carrera P., Bardoni B., Diebold C., Schejter E., Mandel J.-L., Giangrande A.

Dev. Biol. 274:260-270(2004) · UniProtKB (2) · Mapped (7)

Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles.

Khandjian E.W., Huot M.E., Tremblay S., Davidovic L., Mazroui R., Bardoni B.

Proc. Natl. Acad. Sci. U.S.A. 101:13357-13362(2004) · Mapped (11)

Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo.

Mientjes E.J., Willemsen R., Kirkpatrick L.L., Nieuwenhuizen I.M., Hoogeveen-Westerveld M., Verweij M., Reis S., Bardoni B., Hoogeveen A.T., Oostra B.A. et al.

Hum. Mol. Genet. 13:1291-1302(2004) · UniProtKB (1) · Mapped (11)

CYFIP2 is highly abundant in CD4+ cells from multiple sclerosis patients and is involved in T cell adhesion.

Mayne M., Moffatt T., Kong H., McLaren P.J., Fowke K.R., Becker K.G., Namaka M., Schenck A., Bardoni B., Bernstein C.N. et al.

Eur. J. Immunol. 34:1217-1227(2004) · UniProtKB (1)

The N-terminus of the fragile X mental retardation protein contains a novel domain involved in dimerization and RNA binding.

Adinolfi S., Ramos A., Martin S.R., Dal Piaz F., Pucci P., Bardoni B., Mandel J.L., Pastore A.

Biochemistry 42:10437-10444(2003) · Mapped (8)

NUFIP1 (nuclear FMRP interacting protein 1) is a nucleocytoplasmic shuttling protein associated with active synaptoneurosomes.

Bardoni B., Willemsen R., Weiler I.J., Schenck A., Severijnen L.A., Hindelang C., Lalli E., Mandel J.L.

Exp. Cell Res. 289:95-107(2003)

82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization.

Bardoni B., Castets M., Huot M.-E., Schenck A., Adinolfi S., Corbin F., Pastore A., Khandjian E.W., Mandel J.-L.

Hum. Mol. Genet. 12:1689-1698(2003) · UniProtKB (3) · Mapped (2)

CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.

Schenck A., Bardoni B., Langmann C., Harden N., Mandel J.-L., Giangrande A.

Neuron 38:887-898(2003) · UniProtKB (3) · Mapped (10)

Novel features of dFMR1, the Drosophila orthologue of the fragile X mental retardation protein.

Schenck A., Van de Bor V., Bardoni B., Giangrande A.

Neurobiol. Dis. 11:53-63(2002) · Mapped (2)

A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P.

Schenck A., Bardoni B., Moro A., Bagni C., Mandel J.-L.

Proc. Natl. Acad. Sci. U.S.A. 98:8844-8849(2001) · UniProtKB (7) · Mapped (34)

A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein.

Bardoni B., Schenck A., Mandel J.-L.

Hum. Mol. Genet. 8:2557-2566(1999) · UniProtKB (4) · Mapped (1)

Novel isoforms of the fragile X related protein FXR1P are expressed during myogenesis.

Khandjian E.W., Bardoni B., Corbin F., Sittler A., Giroux S., Heitz D., Tremblay S., Pinset C., Montarras D., Rousseau F. et al.

Hum. Mol. Genet. 7:2121-2128(1998)

A transcriptional silencing domain in DAX-1 whose mutation causes adrenal hypoplasia congenita.

Lalli E., Bardoni B., Zazopoulos E., Wurtz J.-M., Strom T.M., Moras D., Sassone-Corsi P.

Mol. Endocrinol. 11:1950-1960(1997) · UniProtKB (1)

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