1 - 25 of 101 results for author:"Barbacid M." in Literature citations
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| EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma. Navas C., Hernandez-Porras I., Schuhmacher A.J., Sibilia M., Guerra C., Barbacid M. Cancer Cell 22:318-330(2012) · Mapped (5) |
| Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion. Ganuza M., Saiz-Ladera C., Canamero M., Gomez G., Schneider R., Blasco M.A., Pisano D., Paramio J.M., Santamaria D., Barbacid M. EMBO J. 31:2498-2510(2012) · Mapped (27) |
| Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras. Matallanas D., Romano D., Al-Mulla F., O'Neill E., Al-Ali W., Crespo P., Doyle B., Nixon C., Sansom O., Drosten M. et al. Mol. Cell 44:893-906(2011) · Mapped (17) |
| Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence. Guerra C., Collado M., Navas C., Schuhmacher A.J., Hernandez-Porras I., Canamero M., Rodriguez-Justo M., Serrano M., Barbacid M. Cancer Cell 19:728-739(2011) · Mapped (20) |
| Toll-like receptor-4 (TLR4) down-regulates microRNA-107, increasing macrophage adhesion via cyclin-dependent kinase 6. Hennessy E.J., Sheedy F.J., Santamaria D., Barbacid M., O'Neill L.A. J. Biol. Chem. 286:25531-25539(2011) · Mapped (2) |
| c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma. Blasco R.B., Francoz S., Santamaria D., Canamero M., Dubus P., Charron J., Baccarini M., Barbacid M. Cancer Cell 19:652-663(2011) · Mapped (54) |
| Constitutive activation of B-Raf in the mouse germ line provides a model for human cardio-facio-cutaneous syndrome. Urosevic J., Sauzeau V., Soto-Montenegro M.L., Reig S., Desco M., Wright E.M., Canamero M., Mulero F., Ortega S., Bustelo X.R. et al. Proc. Natl. Acad. Sci. U.S.A. 108:5015-5020(2011) · Mapped (30) |
| Cdk6-dependent regulation of G(1) length controls adult neurogenesis. Beukelaers P., Vandenbosch R., Caron N., Nguyen L., Belachew S., Moonen G., Kiyokawa H., Barbacid M., Santamaria D., Malgrange B. Stem Cells 29:713-724(2011) · UniProtKB (1) |
| Loss of nuclear receptor RXRalpha in epidermal keratinocytes promotes the formation of Cdk4-activated invasive melanomas. Hyter S., Bajaj G., Liang X., Barbacid M., Ganguli-Indra G., Indra A.K. Pigment Cell Melanoma Res 23:635-648(2010) · Mapped (11) |
| A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma. Puyol M., Martin A., Dubus P., Mulero F., Pizcueta P., Khan G., Guerra C., Santamaria D., Barbacid M. Cancer Cell 18:63-73(2010) · Mapped (28) |
| DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS. Lauth M., Bergstrom A., Shimokawa T., Tostar U., Jin Q., Fendrich V., Guerra C., Barbacid M., Toftgard R. Nat. Struct. Mol. Biol. 17:718-725(2010) · Mapped (12) |
| Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival. Drosten M., Dhawahir A., Sum E.Y., Urosevic J., Lechuga C.G., Esteban L.M., Castellano E., Guerra C., Santos E., Barbacid M. EMBO J. 29:1091-1104(2010) · Mapped (16) |
| Cdk2 suppresses cellular senescence induced by the c-myc oncogene. Campaner S., Doni M., Hydbring P., Verrecchia A., Bianchi L., Sardella D., Schleker T., Perna D., Tronnersjo S., Murga M. et al. Nat. Cell Biol. 12:54-9; sup pp 2010:1-14(2010) · Mapped (4) |
| The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma. Martinez-Romero C., Rooman I., Skoudy A., Guerra C., Molero X., Gonzalez A., Iglesias M., Lobato T., Bosch A., Barbacid M. et al. J. Pathol. 219:205-213(2009) · Mapped (32) |
| Mice thrive without Cdk4 and Cdk2. Barriere C., Santamaria D., Cerqueira A., Galan J., Martin A., Ortega S., Malumbres M., Dubus P., Barbacid M. Mol Oncol 1:72-83(2007) · Mapped (24) |
| Cell cycle, CDKs and cancer: a changing paradigm. Malumbres M., Barbacid M. Nat. Rev. Cancer 9:153-166(2009) · UniProtKB (6) |
| A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition. Schuhmacher A.J., Guerra C., Sauzeau V., Canamero M., Bustelo X.R., Barbacid M. J. Clin. Invest. 118:2169-2179(2008) · Mapped (46) |
| Postnatal Schwann cell proliferation but not myelination is strictly and uniquely dependent on cyclin-dependent kinase 4 (cdk4). Atanasoski S., Boentert M., De Ventura L., Pohl H., Baranek C., Beier K., Young P., Barbacid M., Suter U. Mol. Cell. Neurosci. 37:519-527(2008) · Mapped (17) |
| Cdk1 is sufficient to drive the mammalian cell cycle. Santamaria D., Barriere C., Cerqueira A., Hunt S., Tardy C., Newton K., Caceres J.F., Dubus P., Malumbres M., Barbacid M. |
| p38alpha MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation. Ventura J.J., Tenbaum S., Perdiguero E., Huth M., Guerra C., Barbacid M., Pasparakis M., Nebreda A.R. Nat. Genet. 39:750-758(2007) · Mapped (18) |
| Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice. Guerra C., Schuhmacher A.J., Canamero M., Grippo P.J., Verdaguer L., Perez-Gallego L., Dubus P., Sandgren E.P., Barbacid M. Cancer Cell 11:291-302(2007) · Mapped (7) |
| Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo. Sansom O.J., Meniel V., Wilkins J.A., Cole A.M., Oien K.A., Marsh V., Jamieson T.J., Guerra C., Ashton G.H., Barbacid M. et al. Proc. Natl. Acad. Sci. U.S.A. 103:14122-14127(2006) · Mapped (18) |
| Rapid growth of invasive metastatic melanoma in carcinogen-treated hepatocyte growth factor/scatter factor-transgenic mice carrying an oncogenic CDK4 mutation. Tormo D., Ferrer A., Gaffal E., Wenzel J., Basner-Tschakarjan E., Steitz J., Heukamp L.C., Gutgemann I., Buettner R., Malumbres M. et al. Am. J. Pathol. 169:665-672(2006) · Mapped (14) |
| Cell cycle and cancer: genetic analysis of the role of cyclin-dependent kinases. Barbacid M., Ortega S., Sotillo R., Odajima J., Martin A., Santamaria D., Dubus P., Malumbres M. Cold Spring Harb. Symp. Quant. Biol. 70:233-240(2005) · Mapped (17) |
| Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4R24C/R24C/TPras mice. Hacker E., Muller H.K., Irwin N., Gabrielli B., Lincoln D., Pavey S., Powell M.B., Malumbres M., Barbacid M., Hayward N. et al. Cancer Res. 66:2946-2952(2006) · Mapped (10) |