| A point mutation in the EGF-4 domain of beta(3) integrin is responsible for the formation of the Sec(a) platelet alloantigen and affects receptor function. Sachs U.J., Bakchoul T., Eva O., Giptner A., Bein G., Aster R.H., Gitter M., Peterson J., Santoso S.
Thromb. Haemost. 107:80-87(2012) · Mapped (5) |
| Antibodies associated with heparin-induced thrombocytopenia (HIT) inhibit activated protein C generation: new insights into the prothrombotic nature of HIT. Kowalska M.A., Krishnaswamy S., Rauova L., Zhai L., Hayes V., Amirikian K., Esko J.D., Bougie D.W., Aster R.H., Cines D.B. et al.
Blood 118:2882-2888(2011) · Mapped (4) |
| The neutrophil alloantigen HNA-3a (5b) is located on choline transporter-like protein 2 and appears to be encoded by an R>Q154 amino acid substitution. Curtis B.R., Cox N.J., Sullivan M.J., Konkashbaev A., Bowens K., Hansen K., Aster R.H.
Blood 115:2073-2076(2010) · Mapped (3) |
| Eptifibatide-induced thrombocytopenia and thrombosis in humans require FcgammaRIIa and the integrin beta3 cytoplasmic domain. Gao C., Boylan B., Bougie D., Gill J.C., Birenbaum J., Newman D.K., Aster R.H., Newman P.J.
J. Clin. Invest. 119:504-511(2009) · Mapped (7) |
| Fine specificity of drug-dependent antibodies reactive with a restricted domain of platelet GPIIIA. Peterson J.A., Nelson T.N., Kanack A.J., Aster R.H.
Blood 111:1234-1239(2008) · Mapped (5) |
| Platelet factor 4 differentially modulates CD4+CD25+ (regulatory) versus CD4+CD25- (nonregulatory) T cells. Liu C.Y., Battaglia M., Lee S.H., Sun Q.H., Aster R.H., Visentin G.P.
J. Immunol. 174:2680-2686(2005) · Mapped (1) |
| A site involving the "hybrid" and PSI homology domains of GPIIIa (beta 3-integrin subunit) is a common target for antibodies associated with quinine-induced immune thrombocytopenia. Peterson J.A., Nyree C.E., Newman P.J., Aster R.H.
Blood 101:937-942(2003) · Mapped (5) |
| The human platelet alloantigens, PlA1 and PlA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing. Newman P.J., Derbes R.S., Aster R.H.
J. Clin. Invest. 83:1778-1781(1989) · UniProtKB (1) |
| Polymorphism of human platelet membrane glycoprotein IIb associated with the Baka/Bakb alloantigen system. Lyman S., Aster R.H., Visentin G.P., Newman P.J.
Blood 75:2343-2348(1990) · UniProtKB (1) |
| An amino acid polymorphism within the RGD binding domain of platelet membrane glycoprotein IIIa is responsible for the formation of the Pena/Penb alloantigen system. Wang R., Furihata K., McFarland J.G., Friedman K., Aster R.H., Newman P.J.
J. Clin. Invest. 90:2038-2043(1992) · UniProtKB (1) |
