1 - 25 of 47 results for author:"Ashkenazi A." in Literature citations
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| Proapoptotic activation of death receptor 5 on tumor endothelial cells disrupts the vasculature and reduces tumor growth. Wilson N.S., Yang A., Yang B., Couto S., Stern H., Gogineni A., Pitti R., Marsters S., Weimer R.M., Singh M. et al. Cancer Cell 22:80-90(2012) · Mapped (13) |
| Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models. French D.M., Lin B.C., Wang M., Adams C., Shek T., Hotzel K., Bolon B., Ferrando R., Blackmore C., Schroeder K. et al. PLoS ONE 7:e36713-e36713(2012) · Mapped (3) |
| Distinct involvement of the Gab1 and Grb2 adaptor proteins in signal transduction by the related receptor tyrosine kinases RON and MET. Chaudhuri A., Xie M.H., Yang B., Mahapatra K., Liu J., Marsters S., Bodepudi S., Ashkenazi A. J. Biol. Chem. 286:32762-32774(2011) · UniProtKB (2) · Mapped (10) |
| TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8. Ikner A., Ashkenazi A. J. Biol. Chem. 286:21546-21554(2011) · Mapped (8) |
| NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-alpha feedforward signaling. Biton S., Ashkenazi A. Cell 145:92-103(2011) · Mapped (11) |
| Viral envelope protein folding and membrane hemifusion are enhanced by the conserved loop region of HIV-1 gp41. Ashkenazi A., Viard M., Wexler-Cohen Y., Blumenthal R., Shai Y. FASEB J. 25:2156-2166(2011) · Mapped (5) |
| Development of immunohistochemistry assays to assess GALNT14 and FUT3/6 in clinical trials of dulanermin and drozitumab. Stern H.M., Padilla M., Wagner K., Amler L., Ashkenazi A. Clin. Cancer Res. 16:1587-1596(2010) · Mapped (9) |
| Sporadic hemiplegic migraine and epilepsy associated with CACNA1A gene mutation. Zangaladze A., Asadi-Pooya A.A., Ashkenazi A., Sperling M.R. Epilepsy Behav 17:293-295(2010) · Mapped (8) |
| X chromosome-linked inhibitor of apoptosis regulates cell death induction by proapoptotic receptor agonists. Varfolomeev E., Alicke B., Elliott J.M., Zobel K., West K., Wong H., Scheer J.M., Ashkenazi A., Gould S.E., Fairbrother W.J. et al. J. Biol. Chem. 284:34553-34560(2009) · Mapped (15) |
| Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling. Jin Z., Li Y., Pitti R., Lawrence D., Pham V.C., Lill J.R., Ashkenazi A. Cell 137:721-735(2009) · Mapped (7) |
| Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice. Qing J., Du X., Chen Y., Chan P., Li H., Wu P., Marsters S., Stawicki S., Tien J., Totpal K. et al. J. Clin. Invest. 119:1216-1229(2009) · Mapped (10) |
| Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL). Ashkenazi A., Holland P., Eckhardt S.G. J. Clin. Oncol. 26:3621-3630(2008) · Mapped (3) |
| Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5. Adams C., Totpal K., Lawrence D., Marsters S., Pitti R., Yee S., Ross S., Deforge L., Koeppen H., Sagolla M. et al. Cell Death Differ. 15:751-761(2008) · Mapped (8) |
| Duffy antigen/receptor for chemokines (DARC) attenuates angiogenesis by causing senescence in endothelial cells. Xu L., Ashkenazi A., Chaudhuri A. Angiogenesis 10:307-318(2007) · Mapped (18) |
| Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL. Wagner K.W., Punnoose E.A., Januario T., Lawrence D.A., Pitti R.M., Lancaster K., Lee D., von Goetz M., Yee S.F., Totpal K. et al. Nat. Med. 13:1070-1077(2007) · Mapped (3) |
| Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models. Desnoyers L.R., Pai R., Ferrando R.E., Hotzel K., Le T., Ross J., Carano R., D'Souza A., Qing J., Mohtashemi I. et al. Oncogene 27:85-97(2008) · Mapped (12) |
| Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival. Holst C.R., Bou-Reslan H., Gore B.B., Wong K., Grant D., Chalasani S., Carano R.A., Frantz G.D., Tessier-Lavigne M., Bolon B. et al. PLoS ONE 2:e575-e575(2007) · Mapped (6) |
| Delineation of the cell-extrinsic apoptosis pathway in the zebrafish. Eimon P.M., Kratz E., Varfolomeev E., Hymowitz S.G., Stern H., Zha J., Ashkenazi A. Cell Death Differ. 13:1619-1630(2006) · UniProtKB (12) · Mapped (39) |
| Functional characterization of the Bcl-2 gene family in the zebrafish. Kratz E., Eimon P.M., Mukhyala K., Stern H., Zha J., Strasser A., Hart R., Ashkenazi A. Cell Death Differ. 13:1631-1640(2006) · UniProtKB (7) · Mapped (39) |
| Activation of the proapoptotic death receptor DR5 by oligomeric peptide and antibody agonists. Li B., Russell S.J., Compaan D.M., Totpal K., Marsters S.A., Ashkenazi A., Cochran A.G., Hymowitz S.G., Sidhu S.S. J. Mol. Biol. 361:522-536(2006) · Mapped (1) |
| TWEAK attenuates the transition from innate to adaptive immunity. Maecker H., Varfolomeev E., Kischkel F., Lawrence D., LeBlanc H., Lee W., Hurst S., Danilenko D., Li J., Filvaroff E. et al. Cell 123:931-944(2005) · Mapped (3) |
| TNF-related apoptosis-inducing ligand (TRAIL)/Apo2L suppresses experimental autoimmune encephalomyelitis in mice. Cretney E., McQualter J.L., Kayagaki N., Yagita H., Bernard C.C., Grewal I.S., Ashkenazi A., Smyth M.J. Immunol. Cell Biol. 83:511-519(2005) · Mapped (7) |
| Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis. Sharp D.A., Lawrence D.A., Ashkenazi A. J. Biol. Chem. 280:19401-19409(2005) · Mapped (8) |
| Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (DR) 5 than DR4 to apoptosis signaling. Kelley R.F., Totpal K., Lindstrom S.H., Mathieu M., Billeci K., Deforge L., Pai R., Hymowitz S.G., Ashkenazi A. J. Biol. Chem. 280:2205-2212(2005) · Mapped (11) |
| Tumor necrosis factor: an apoptosis JuNKie? Varfolomeev E.E., Ashkenazi A. Cell 116:491-497(2004) · Mapped (24) |