1 - 25 of 144 results for author:"Appella E." in Literature citations
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| p53 N-terminal phosphorylation: a defining layer of complex regulation. Jenkins L.M., Durell S.R., Mazur S.J., Appella E. Carcinogenesis 33:1441-1449(2012) · Mapped (11) |
| Regulation of the Wip1 phosphatase and its effects on the stress response. Lowe J., Cha H., Lee M.O., Mazur S.J., Appella E., Fornace A.J. Jr. Front. Biosci. 17:1480-1498(2012) · Mapped (6) |
| Wip1 promotes RUNX2-dependent apoptosis in p53-negative tumors and protects normal tissues during treatment with anticancer agents. Goloudina A.R., Tanoue K., Hammann A., Fourmaux E., Le Guezennec X., Bulavin D.V., Mazur S.J., Appella E., Garrido C., Demidov O.N. Proc. Natl. Acad. Sci. U.S.A. 109:E68-75(2012) · Mapped (2) |
| Inhibition of multidrug resistance-linked P-glycoprotein (ABCB1) function by 5'-fluorosulfonylbenzoyl 5'-adenosine: evidence for an ATP analogue that interacts with both drug-substrate-and nucleotide-binding sites. Ohnuma S., Chufan E., Nandigama K., Jenkins L.M., Durell S.R., Appella E., Sauna Z.E., Ambudkar S.V. Biochemistry 50:3724-3735(2011) · Mapped (9) |
| Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence. Fujita K., Horikawa I., Mondal A.M., Jenkins L.M., Appella E., Vojtesek B., Bourdon J.C., Lane D.P., Harris C.C. Nat. Cell Biol. 12:1205-1212(2010) · Mapped (33) |
| The MBT repeats of L3MBTL1 link SET8-mediated p53 methylation at lysine 382 to target gene repression. West L.E., Roy S., Lachmi-Weiner K., Hayashi R., Shi X., Appella E., Kutateladze T.G., Gozani O. J. Biol. Chem. 285:37725-37732(2010) · UniProtKB (4) · Mapped (36) |
| Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo. Niida H., Murata K., Shimada M., Ogawa K., Ohta K., Suzuki K., Fujigaki H., Khaw A.K., Banerjee B., Hande M.P. et al. EMBO J. 29:3558-3570(2010) · Mapped (9) |
| Cooperative interactions at the SLP-76 complex are critical for actin polymerization. Barda-Saad M., Shirasu N., Pauker M.H., Hassan N., Perl O., Balbo A., Yamaguchi H., Houtman J.C., Appella E., Schuck P. et al. EMBO J. 29:2315-2328(2010) · Mapped (10) |
| Structural insight into p53 recognition by the 53BP1 tandem Tudor domain. Roy S., Musselman C.A., Kachirskaia I., Hayashi R., Glass K.C., Nix J.C., Gozani O., Appella E., Kutateladze T.G. J. Mol. Biol. 398:489-496(2010) · Mapped (38) |
| p53 binding to nucleosomal DNA depends on the rotational positioning of DNA response element. Sahu G., Wang D., Chen C.B., Zhurkin V.B., Harrington R.E., Appella E., Hager G.L., Nagaich A.K. J. Biol. Chem. 285:1321-1332(2010) · Mapped (32) |
| Control of p53 multimerization by Ubc13 is JNK-regulated. Topisirovic I., Gutierrez G.J., Chen M., Appella E., Borden K.L., Ronai Z.A. Proc. Natl. Acad. Sci. U.S.A. 106:12676-12681(2009) · Mapped (39) |
| Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1. Yun S.M., Moulaei T., Lim D., Bang J.K., Park J.E., Shenoy S.R., Liu F., Kang Y.H., Liao C., Soung N.K. et al. Nat. Struct. Mol. Biol. 16:876-882(2009) · UniProtKB (1) |
| Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation. Feng H., Jenkins L.M.M., Durell S.R., Hayashi R., Mazur S.J., Cherry S., Tropea J.E., Miller M., Wlodawer A., Appella E. et al. |
| Two distinct motifs within the p53 transactivation domain bind to the Taz2 domain of p300 and are differentially affected by phosphorylation. Jenkins L.M., Yamaguchi H., Hayashi R., Cherry S., Tropea J.E., Miller M., Wlodawer A., Appella E., Mazur S.J. Biochemistry 48:1244-1255(2009) · Mapped (35) |
| Induction of PPM1D following DNA-damaging treatments through a conserved p53 response element coincides with a shift in the use of transcription initiation sites. Rossi M., Demidov O.N., Anderson C.W., Appella E., Mazur S.J. Nucleic Acids Res. 36:7168-7180(2008) · Mapped (7) |
| Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signaling. Kachirskaia I., Shi X., Yamaguchi H., Tanoue K., Wen H., Wang E.W., Appella E., Gozani O. J. Biol. Chem. 283:34660-34666(2008) · Mapped (38) |
| Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Wang R.H., Sengupta K., Li C., Kim H.S., Cao L., Xiao C., Kim S., Xu X., Zheng Y., Chilton B. et al. Cancer Cell 14:312-323(2008) · Mapped (29) |
| Hormone-dependent nuclear export of estradiol receptor and DNA synthesis in breast cancer cells. Lombardi M., Castoria G., Migliaccio A., Barone M.V., Di Stasio R., Ciociola A., Bottero D., Yamaguchi H., Appella E., Auricchio F. J. Cell Biol. 182:327-340(2008) · Mapped (58) |
| Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence. Kumamoto K., Spillare E.A., Fujita K., Horikawa I., Yamashita T., Appella E., Nagashima M., Takenoshita S., Yokota J., Harris C.C. Cancer Res. 68:3193-3203(2008) · Mapped (35) |
| Wip1 phosphatase regulates p53-dependent apoptosis of stem cells and tumorigenesis in the mouse intestine. Demidov O.N., Timofeev O., Lwin H.N., Kek C., Appella E., Bulavin D.V. Cell Stem Cell 1:180-190(2007) · Mapped (29) |
| PML enhances the regulation of p53 by CK1 in response to DNA damage. Alsheich-Bartok O., Haupt S., Alkalay-Snir I., Saito S., Appella E., Haupt Y. Oncogene 27:3653-3661(2008) · Mapped (51) |
| Quantitative proteomics analysis of the effects of ionizing radiation in wild type and p53 K317R knock-in mouse thymocytes. Jenkins L.M., Mazur S.J., Rossi M., Gaidarenko O., Xu Y., Appella E. Mol. Cell Proteomics 7:716-727(2008) · Mapped (18) |
| GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers. Kang T., Wei Y., Honaker Y., Yamaguchi H., Appella E., Hung M.C., Piwnica-Worms H. Cancer Cell 13:36-47(2008) · Mapped (7) |
| The Wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases. Yamaguchi H., Durell S.R., Chatterjee D.K., Anderson C.W., Appella E. Biochemistry 46:12594-12603(2007) · Mapped (6) |
| Single MHC mutation eliminates enthalpy associated with T cell receptor binding. Miller P.J., Pazy Y., Conti B., Riddle D., Appella E., Collins E.J. J. Mol. Biol. 373:315-327(2007) · UniProtKB (1) · Mapped (4) |