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Molecular cloning and sequencing of a carp cDNA encoding mitogen-activated protein kinase kinase.

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Huang C.-J., Lee M.-S., Chang G.-D., Huang F.-L., Lo T.-B.

We have cloned a full-length cDNA encoding the mitogen-activated protein kinase kinase (MKK) from a carp liver cDNA library. The cDNA contains 1970 bp with a single open reading frame encoding a 397 amino acid protein. By comparing with known MKK sequences from other species, carp MKK is 78%, 80%, 76% and 58% identical to rat MKK1, rat MKK2, Xenopus MKK and Drosophila MKK.

Biochim. Biophys. Acta 1220:223-225(1994) [ PubMed | SRS | CiteXplore ]