The adenylate cyclase catalytic domain of Streptomyces coelicolor is carboxy-terminal.
Danchin A., Pidoux J., Krin E., Thompson C.J., Ullmann A.
A DNA fragment of Streptomyces coelicolor encoding the carboxy-terminal catalytic domain of adenylate cyclase was cloned, sequenced and expressed in an Escherichia coli cya-defective strain where it produced nanomole levels of cAMP. The amino acid sequence of the enzyme displays similarities with the Brevibacterium liquefaciens pyruvate regulated adenylate cyclase.
FEMS Microbiol. Lett. 114:145-152(1993) [ PubMed | SRS | CiteXplore ]
