Molecular characterization of the gene encoding high-level mupirocin resistance in Staphylococcus aureus J2870.
Hodgson J.E., Curnock S.P., Dyke K.G.H., Morris R., Sylvester D.R., Gross M.S.
The nucleotide sequence of the ileS gene conferring high-level resistance to mupirocin in Staphylococcus aureus J2870 has been determined. The gene sequence is substantially different from that of the native ileS gene of S. aureus, indicating that high-level resistance to mupirocin results from the acquisition of a novel ileS gene.
Antimicrob. Agents Chemother. 38:1205-1208(1994) [ PubMed | SRS | CiteXplore ]
