Sequence of a chicken erythroblast mono(ADP-ribosyl)transferase-encoding gene and its upstream region.
We have cloned the MADPRT gene encoding the 300-amino-acid mono(ADP-ribosyl)transferase (MADPRT) from chicken erythroblasts. The protein has homology to the rabbit and human skeletal muscle (50% identity) and two chicken heterophil (52% identity) NAD+:arginine MADPRT. The active site region is particularly conserved. The upstream region of the MADPRT gene from erythroblasts has several features characteristic of promoter sequences.
Gene 164:371-372(1995) [ PubMed | SRS | CiteXplore ]



