Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome.
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Greenleaf A.L., Kelly J.L., Lehman I.R.
A 4-kilobase DNA fragment carried by a recombinant lambda gt11 bacteriophage appears to contain most of the coding information for the 145-kDa subunit of the Saccharomyces cerevisiae mitochondrial RNA polymerase. The RPO41 gene is located on chromosome VI, as determined by hybridization to electrophoretically separated yeast chromosomes. Hybridization and gene disruption/replacement experiments show that the RPO41 gene exists in a single copy and that its product is required for transcription and maintenance of the mitochondrial genome.
Proc. Natl. Acad. Sci. U.S.A. 83:3391-3394(1986) [PubMed] [Europe PMC]