Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Polymorphic human glucose transporter gene (GLUT) is on chromosome 1p31.3----p35.

Shows T.B., Eddy R.L., Byers M.G., Fukushima Y., Dehaven C.R., Murray J.C., Bell G.I.

The glucose transporter is a membrane glycoprotein that is involved in the uptake of glucose by most, if not all, animal cells. A cloned cDNA that encodes the human protein was used to map the gene to a specific chromosomal region and to identify a DNA polymorphism. The human gene (designated GLUT) was assigned to chromosome 1p31.3----p35 by hybridization of the probe to DNA from a panel of human-mouse somatic cell hybrids containing different human chromosomes and by in situ hybridization to isolated metaphase chromosomes. The most likely location of GLUT is in 1p33. A common two-allele restriction-fragment-length polymorphism was identified with Xba I.

Diabetes 36:546-549(1987) [PubMed] [Europe PMC]