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Nucleotide sequence of SHV-2 beta-lactamase gene.

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Garbarg-Chenon A., Godard V., Labia R., Nicolas J.C.

The nucleotide sequence of plasmid-mediated beta-lactamase SHV-2 from Salmonella typhimurium (SHV-2pHT1) was determined. The gene was very similar to chromosomally encoded beta-lactamase LEN-1 of Klebsiella pneumoniae. Compared with the sequence of the Escherichia coli SHV-2 enzyme (SHV-2E.coli) obtained by protein sequencing, the deduced amino acid sequence of SHV-2pHT1 differed by three amino acid substitutions.

Antimicrob. Agents Chemother. 34:1444-1446(1990) [ PubMed | SRS | CiteXplore ]