Complete genome sequence of Mycoplasma haemofelis, a hemotropic mycoplasma.
Barker E.N., Helps C.R., Peters I.R., Darby A.C., Radford A.D., Tasker S.
Here, we present the genome sequence of Mycoplasma haemofelis strain Langford 1, representing the first hemotropic mycoplasma (hemoplasma) species to be completely sequenced and annotated. Originally isolated from a cat with hemolytic anemia, this strain induces severe hemolytic anemia when inoculated into specific-pathogen-free-derived cats. The genome sequence has provided insights into the biology of this uncultivatable hemoplasma and has identified potential molecular mechanisms underlying its pathogenicity.