Sud N., Sharma R., Ray R., Chattopadhyay T.K., Ralhan R.

Cancer Lett. 233:265-270(2006) GeneRIF 9289 · Mapped (6)
Increased expression of GPCR56 is associated with esophageal squamous cell carcinoma GeneRIF 9289

Xu L., Begum S., Hearn J.D., Hynes R.O.

Proc. Natl. Acad. Sci. U.S.A. 103:9023-9028(2006) GeneRIF 9289 · Mapped (17)
Results show that GPR56 binds specifically to tissue transglutaminase TG2 a widespread component of tissue and tumor stroma previously implicated as an inhibitor of tumor progression. GeneRIF 9289

Xu L., Hynes R.O.

Cell Cycle 6:160-165(2007) GeneRIF 9289 · Mapped (14)
Review describes the expression of a ligand that interacts with GPR56 in metastatic melanoma cells as TG2 a major crosslinking enzyme in the tumor extracellular matrix. GeneRIF 9289

Huang Y., Fan J., Yang J., Zhu G.Z.

Mol. Cell. Biochem. 308:133-139(2008) GeneRIF 9289 · Mapped (7)
These results define the biochemical properties of GPR56 protein and suggest that the expression of GPR56 protein is suppressed in human pancreatic cancer cells. GeneRIF 9289

Ke N., Ma H., Diedrich G., Chionis J., Liu G., Yu D.H., Wong-Staal F., Li Q.X.

Biochem. Biophys. Res. Commun. 366:314-320(2008) GeneRIF 9289 · Mapped (6)
We have shown that GPR56 GPS mutant protein is defective in cleavage and surface localization while non-GPS mutant proteins are cleaved normally but still defective in surface localization. GeneRIF 9289

Parrini E., Ferrari A.R., Dorn T., Walsh C.A., Guerrini R.

Epilepsia 50:1344-1353(2009) GeneRIF 9289 · Mapped (6)
This study reported that three consanguineous families in which four affected individuals with Bilateral frontoparietal polymicrogyria and GPR56 mutations had Lennox-Gastaut syndrome. GeneRIF 9289

Bai Y., Du L., Shen L., Zhang Y., Zhang L.

Neuroreport 20:918-922(2009) GeneRIF 9289 · Mapped (6)
Our data suggest that GPR56 can be used as an NSC/NPC marker within the neural cell lineage especially in combination with nestin. GeneRIF 9289

Kim J.E., Han J.M., Park C.R., Shin K.J., Ahn C., Seong J.Y., Hwang J.I.

J. Cancer Res. Clin. Oncol. 136:47-53(2010) GeneRIF 9289 · Mapped (6)
Results suggest that the splicing of GPR56 may induce differential tumorigenic responses owing to their varied ability to activate transcription factors. GeneRIF 9289

Della Chiesa M., Falco M., Parolini S., Bellora F., Petretto A., Romeo E., Balsamo M., Gambarotti M., Scordamaglia F., Tabellini G. et al.

Int. Immunol. 22:91-100(2010) GeneRIF 9289 · Mapped (6)
Identify GPR56 as a novel marker capable of discriminating different natural killer cells subsets. GeneRIF 9289

Yokoyama K., Urashima M., Ohkido I., Kono T., Yoshida T., Muramatsu M., Niu T., Hosoya T.

Nephron Clin Pract 115:c237-43(2010) GeneRIF 9289 · Mapped (557)
Observational study of gene-disease association. (HuGE Navigator) GeneRIF 9289

Kausar T., Sharma R., Hasan M.R., Tripathi S.C., Saraya A., Chattopadhyay T.K., Gupta S.D., Ralhan R.

Cancer Invest. 29:42-48(2011) GeneRIF 9289 · Mapped (14)
A significant correlation between GPR56 TG2 and NF-kappaB was observed that correlated with nodal metastasis and tumor invasion in esophageal squamous cell carcinoma. GeneRIF 9289

Chiang N.Y., Hsiao C.C., Huang Y.S., Chen H.Y., Hsieh I.J., Chang G.W., Lin H.H.

J. Biol. Chem. 286:14215-14225(2011) GeneRIF 9289 · Mapped (7)
GPR56 mutations cause bilateral frontoparietal polymicrogyria via multiple mechanisms GeneRIF 9289

Paavola K.J., Stephenson J.R., Ritter S.L., Alter S.P., Hall R.A.

J. Biol. Chem. 286:28914-28921(2011) GeneRIF 9289 · Mapped (6)
The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity. GeneRIF 9289

Luo R., Yang H.M., Jin Z., Halley D.J., Chang B.S., MacPherson L., Brueton L., Piao X.

Pediatr. Neurol. 45:49-53(2011) GeneRIF 9289 · Mapped (6)
study reports a novel missense mutation of GPR56 E496K identified in a consanguineous pedigree with bilateral frontoparietal polymicrogyria GeneRIF 9289

Yang L., Chen G., Mohanty S., Scott G., Fazal F., Rahman A., Begum S., Hynes R.O., Xu L.

Cancer Res. 71:5558-5568(2011) GeneRIF 9289 · Mapped (18)
consistent with its suppressive roles in melanoma progression the expression levels of GPR56 are inversely correlated with the malignancy of melanomas in human subjects GeneRIF 9289

Peng Y.M., van de Garde M.D., Cheng K.F., Baars P.A., Remmerswaal E.B., van Lier R.A., Mackay C.R., Lin H.H., Hamann J.

J. Leukoc. Biol. 90:735-740(2011) GeneRIF 9289 · Mapped (6)
GPR56 expression is a common trait of human cytotoxic lymphocytes and might affect the migratory properties of these cells. GeneRIF 9289

Luo R., Jin Z., Deng Y., Strokes N., Piao X.

PLoS ONE 7:e29818-e29818(2012) GeneRIF 9289 · Mapped (9)
Disease-associated mutations prevent GPR56-collagen III interaction. GeneRIF 9289