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8 results for uniprot:Q9Y4B6 in Computationally mapped citations

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Sox9 transactivation and testicular expression of a novel human gene, KIAA0800.

Zhao L.J., Zhang S., Chinnadurai G.

J. Cell. Biochem. 86:277-289(2002) GeneRIF 9730 · Mapped (4)
demonstration that a novel human gene KIAA0800 is preferentially expressed in the testis and is transactivated by Sox9 GeneRIF 9730

Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cells.

Borgne-Sanchez A., Dupont S., Langonne A., Baux L., Lecoeur H., Chauvier D., Lassalle M., Deas O., Briere J.J., Brabant M. et al.

Cell Death Differ. 14:422-435(2007) GeneRIF 9730 · Mapped (2)
Hence this chimeric peptide (TEAM-VP) constitutes the first example of a virus-derived mitochondriotoxic compound as a candidate to kill selectively tumor neo-endothelia. GeneRIF 9730

Anti-tumor activity mediated by protein and peptide transduction of HIV viral protein R (Vpr).

Muthumani K., Lambert V.M., Shanmugam M., Thieu K.P., Choo A.Y., Chung J.C., Satishchandran A., Kim J.J., Weiner D.B., Ugen K.E.

Cancer Biol. Ther. 8:180-187(2009) GeneRIF 9730 · Mapped (2)
Anti-tumor activity mediated by protein and peptide transduction of HIV viral protein R is reported. GeneRIF 9730

The functions of the HIV1 protein Vpr and its action through the DCAF1.DDB1.Cullin4 ubiquitin ligase.

Casey L., Wen X., de Noronha C.M.

Cytokine 51:1-9(2010) GeneRIF 9730 · Mapped (9)
This review focuses on Vpr and its HIV2/SIV counterparts Vpx and Vpr which all engage the DDB1.Cullin4 ubiquitin ligase complex through the DCAF1 adaptor protein. GeneRIF 9730

HIV-1 Vpr loads uracil DNA glycosylase-2 onto DCAF1, a substrate recognition subunit of a cullin 4A-ring E3 ubiquitin ligase for proteasome-dependent degradation.

Ahn J., Vu T., Novince Z., Guerrero-Santoro J., Rapic-Otrin V., Gronenborn A.M.

J. Biol. Chem. 285:37333-37341(2010) GeneRIF 9730 · Mapped (4)
UNG specifically interacts with Vpr forming a heterotrimeric complex with DCAF1. GeneRIF 9730

Vpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tail.

Kim K., Heo K., Choi J., Jackson S., Kim H., Xiong Y., An W.

Mol. Cell. Biol. 32:783-796(2012) GeneRIF 9730 · Mapped (36)
Promoter-localized deacetylation of H3 tails is a prerequisite for VprBP to tether and act as a bona fide inhibitor at p53 target genes. GeneRIF 9730

The HIV1 protein Vpr acts to enhance constitutive DCAF1-dependent UNG2 turnover.

Wen X., Casey Klockow L., Nekorchuk M., Sharifi H.J., de Noronha C.M.

PLoS ONE 7:e30939-e30939(2012) GeneRIF 9730 · Mapped (9)
Vpr acts to enhance constitutive DCAF1-dependent UNG2 turnover. GeneRIF 9730

Autophagy negatively regulates cancer cell proliferation via selectively targeting VPRBP.

Wang B.S., Liu Y.Z., Yang Y., Zhang Y., Hao J.J., Yang H., Wang X.M., Zhang Z.Q., Zhan Q.M., Wang M.R.

Clin. Sci. 124:203-214(2013) GeneRIF 9730 · Mapped (7)
Data show that VPRBP (viral protein R-binding protein)-LC3B (light-chain 3B)/p62(SQSTM1) were in the same protein complex. GeneRIF 9730

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