Grupe A., Li Y., Rowland C., Nowotny P., Hinrichs A.L., Smemo S., Kauwe J.S., Maxwell T.J., Cherny S., Doil L. et al.

Am. J. Hum. Genet. 78:78-88(2006) GAD 566508 GeneRIF 26019 · Mapped (1,497)
Not Associated with NEUROLOGICAL: Alzheimer's disease ; GAD 566508 Observational study of gene-disease association. (HuGE Navigator) GeneRIF 26019

Hosoda N., Kim Y.K., Lejeune F., Maquat L.E.

Nat. Struct. Mol. Biol. 12:893-901(2005) GeneRIF 26019 · UniProtKB (1) · Mapped (8)
During nonsense-mediated mRNA decay CBP80 interacts with Upf1 and promotes the interaction of Upf1 with Upf2 but not with Stau1. GeneRIF 26019

Wittmann J., Hol E.M., Jack H.M.

Mol. Cell. Biol. 26:1272-1287(2006) GeneRIF 26019 · Mapped (5)
UPF2-silenced HeLa cells were impaired in their ability to recognize ectopically expressed aberrant premature termination codon transcripts GeneRIF 26019

Singh G., Jakob S., Kleedehn M.G., Lykke-Andersen J.

Mol. Cell 27:780-792(2007) GeneRIF 26019 · Mapped (12)
The Upf complex communicates with the exon-junction complex and triggers nonsense-mediated decay in the cytoplasm. GeneRIF 26019

Cronin S., Tomik B., Bradley D.G., Slowik A., Hardiman O.

Eur. J. Hum. Genet. 17:213-218(2009) GeneRIF 26019 · Mapped (62)
Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) GeneRIF 26019

Chakrabarti S., Jayachandran U., Bonneau F., Fiorini F., Basquin C., Domcke S., Le Hir H., Conti E.

Mol. Cell 41:693-703(2011) GeneRIF 26019 · UniProtKB (1) · Mapped (8)
Data show that upon binding to Upf2 the regulatory CH domain of Upf1 undergoes a large conformational change causing the catalytic helicase domain to bind RNA less extensively and triggering its helicase activity. GeneRIF 26019

Gehring N.H., Neu-Yilik G., Schell T., Hentze M.W., Kulozik A.E.

Mol. Cell 11:939-949(2003) MINT MINT-265195 · UniProtKB (2) · Mapped (4)
MINT-51076. UPF3B (uniprotkb:Q9BZI7) physically interacts (MI:0915) with UPF2 (uniprotkb:Q9HAU5) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-265195

Lugovic L., Situm M., Buljan M., Poduje S., Sebetic K.

Coll Antropol 31 Suppl 1:7-11(2007) MINT MINT-265195 MINT MINT-265195 MINT MINT-265195 · Mapped (4)
MINT-4791485. INT6 (uniprotkb:Q9UL03) physically interacts (MI:0915) with UPF2 (uniprotkb:Q9HAU5) by anti bait coimmunoprecipitation (MI:0006). From mint MINT MINT-265195 MINT-4791496. UPF2 (uniprotkb:Q9HAU5) physically interacts (MI:0915) with UPF1 (uniprotkb:Q92900) by anti bait coimmunoprecipitation (MI:0006). From mint MINT MINT-265195 MINT-4791511. eIF3b (uniprotkb:P55884-1) physically interacts (MI:0915) with UPF2 (uniprotkb:Q9HAU5) by anti bait coimmunoprecipitation (MI:0006). From mint MINT MINT-265195

Ivanov P.V., Gehring N.H., Kunz J.B., Hentze M.W., Kulozik A.E.

EMBO J. 27:736-747(2008) MINT MINT-265195 MINT MINT-265195 MINT MINT-265195 · Mapped (6)
MINT-6539840. UPF1 (uniprotkb:Q92900) physically interacts (MI:0915) with UPF2 (uniprotkb:Q9HAU5) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-265195 MINT-6539859. UPF1 (uniprotkb:Q92900) physically interacts (MI:0915) with UPF2 (uniprotkb:Q9HAU5) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-265195 MINT-6539883. UPF1 (uniprotkb:Q92900) physically interacts (MI:0915) with UPF2 (uniprotkb:Q9HAU5) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-265195