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17 results for uniprot:Q9BTT9Drop in citationmapping

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Association of muscle glycogen synthase polymorphism with insulin resistance in type 2 diabetic patients.

Motoyama K., Emoto M., Tahara H., Komatsu M., Shoji T., Inaba M., Nishizawa Y.

Metab. Clin. Exp. 52:895-899(2003) GAD 124896 GeneRIF 2997 GAD 124906 · Mapped (8)
Associated with METABOLIC: diabetes, type 2; Cohort 100 type 2 diabetic subjects GAD 124896 Not Associated with METABOLIC: diabetes, type 2; insulin; Cohort 100 type 2 diabetic subjects GAD 124906 Observational study of gene-disease association. (HuGE Navigator); the M416V polymorphism of glycogen synthase 1 gene is not associated with insulin resistance in type 2 diabetes GeneRIF 2997

Variation in GYS1 interacts with exercise and gender to predict cardiovascular mortality.

Fredriksson J., Anevski D., Almgren P., Sjogren M., Lyssenko V., Carlson J., Isomaa B., Taskinen M.R., Groop L., Orho-Melander M.

PLoS ONE 2:e285-e285(2007) GAD 148453 GeneRIF 2997 · Mapped (8)
Associated with CARDIOVASCULAR: cardiac death; GAD 148453 Observational study of gene-disease association. (HuGE Navigator) GeneRIF 2997

A missense mutation of the muscle glycogen synthase gene (M416V) is associated with insulin resistance in the Japanese population.

Shimomura H., Sanke T., Ueda K., Hanabusa T., Sakagashira S., Nanjo K.

Diabetologia 40:947-952(1997) GAD 124904 · Mapped (8)
Associated with METABOLIC: insulin resistance; GAD 124904

The Met416-->Val variant in the glycogen synthase gene: the prevalence and the association with diabetes in a large number of Japanese individuals. Study Group for the Identification of Type 2 Diabetes Genes in Japanese.

Diabetes Care 23:1709-1710(2000) GeneRIF 2997 · Mapped (8)
Observational study of genotype prevalence and gene-disease association. (HuGE Navigator) GeneRIF 2997

The stimulation-induced increase in skeletal muscle glycogen synthase content is impaired in carriers of the glycogen synthase XbaI gene polymorphism.

St-Onge J., Joanisse D.R., Simoneau J.A.

Diabetes 50:195-198(2001) GeneRIF 2997 · Mapped (8)
Observational study of gene-disease association. (HuGE Navigator) GeneRIF 2997

Association of GYS1 and beta(3)-AR gene with postprandial hyperglycemia and serum uric acid in type 2 diabetes mellitus.

Wang G., Li Q., Niu T., Chen C., Xu X.

Chin. Med. J. 115:1308-1311(2002) GeneRIF 2997 GAD 124895 · Mapped (12)
Associated with METABOLIC: diabetes, type 2; Case:102 type 2 diabetes cases;Control:102 spousal controls GAD 124895 Observational study of gene-disease association. (HuGE Navigator) GeneRIF 2997

A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus.

Watanabe I., Tomita A., Shimizu M., Sugawara M., Yasumo H., Koishi R., Takahashi T., Miyoshi K., Nakamura K., Izumi T. et al.

Clin. Pharmacol. Ther. 73:435-455(2003) GeneRIF 2997 · Mapped (204)
Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator) GeneRIF 2997

The primary defect in glycogen synthase activity is not based on increased glycogen synthase kinase-3alpha activity in diabetic myotubes.

Gaster M., Brusgaard K., Handberg A., Hojlund K., Wojtaszewski J.F., Beck-Nielsen H.

Biochem. Biophys. Res. Commun. 319:1235-1240(2004) GeneRIF 2997 · Mapped (10)
Data show that myotubes defective in glycogen synthase (GS) activity express insulin-responsive glycogen synthase kinase-3alpha suggesting that failure of insulin to decrease GS phosphorylation involves abnormal activity of another kinase or phosphatase. GeneRIF 2997

Impact of genetic versus environmental factors on the control of muscle glycogen synthase activation in twins.

Poulsen P., Wojtaszewski J.F., Petersen I., Christensen K., Richter E.A., Beck-Nielsen H., Vaag A.

Diabetes 54:1289-1296(2005) GeneRIF 2997 · Mapped (8)
Phosphorylation at site 2 in the elderly and at site 3a + 3b in young twins had a genetic component. GeneRIF 2997

Determinants of the nucleocytoplasmic shuttling of muscle glycogen synthase.

Cid E., Cifuentes D., Baque S., Ferrer J.C., Guinovart J.J.

FEBS J. 272:3197-3213(2005) GeneRIF 2997 · Mapped (8)
no nuclear export signal was identified in the sequence of the protein the region comprising amino acids 555-633 which has an Arg-rich cluster involved in the allosteric activation is crucial for its nuclear concentration and aggregation. GeneRIF 2997

Association of sixty-one non-synonymous polymorphisms in forty-one hypertension candidate genes with blood pressure variation and hypertension.

Kokubo Y., Tomoike H., Tanaka C., Banno M., Okuda T., Inamoto N., Kamide K., Kawano Y., Miyata T.

Hypertens. Res. 29:611-619(2006) GeneRIF 2997 GAD 148452 · Mapped (110)
Associated with CARDIOVASCULAR: blood pressure, arterial hypertension; GAD 148452 Observational study of gene-disease association. (HuGE Navigator) GeneRIF 2997

Cardiomyopathy and exercise intolerance in muscle glycogen storage disease 0.

Kollberg G., Tulinius M., Gilljam T., Oestman-Smith I., Forsander G., Jotorp P., Oldfors A., Holme E.

N. Engl. J. Med. 357:1507-1514(2007) GeneRIF 2997 · UniProtKB (1) · Mapped (7)
3 siblings were identified with profound muscle glycogen deficiency and homozygous stop mutations in GYS1 GeneRIF 2997

Impaired insulin activation and dephosphorylation of glycogen synthase in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment.

Glintborg D., Hojlund K., Andersen N.R., Hansen B.F., Beck-Nielsen H., Wojtaszewski J.F.

J. Clin. Endocrinol. Metab. 93:3618-3626(2008) GeneRIF 2997 · Mapped (8)
Pioglitazone treatment improved insulin-stimulated glucose metabolism and glycogen synthase activity in PCOS. GeneRIF 2997

Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.

Ruano G., Bernene J., Windemuth A., Bower B., Wencker D., Seip R.L., Kocherla M., Holford T.R., Petit W.A., Hanks S.

Clin. Chim. Acta 400:48-55(2009) GeneRIF 2997 · Mapped (570)
Observational study of gene-disease association gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator) GeneRIF 2997

Dual regulation of muscle glycogen synthase during exercise by activation and compartmentalization.

Prats C., Helge J.W., Nordby P., Qvortrup K., Ploug T., Dela F., Wojtaszewski J.F.

J. Biol. Chem. 284:15692-15700(2009) GeneRIF 2997 · Mapped (8)
After overnight low muscle glycogen level and/or in response to exhausting exercise-induced glycogenolysis GSY is associated with spherical structures at the I-band of sarcomeres. GeneRIF 2997

A candidate gene approach to genetic prognostic factors of IgA nephropathy--a result of Polymorphism REsearch to DIstinguish genetic factors Contributing To progression of IgA Nephropathy (PREDICT-IgAN).

Yamamoto R., Nagasawa Y., Shoji T., Inoue K., Uehata T., Kaneko T., Okada T., Yamauchi A., Tsubakihara Y., Imai E. et al.

Nephrol. Dial. Transplant. 24:3686-3694(2009) GeneRIF 2997 · Mapped (450)
Observational study of gene-disease association. (HuGE Navigator) GeneRIF 2997

Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.

Yoshida T., Kato K., Yokoi K., Oguri M., Watanabe S., Metoki N., Yoshida H., Satoh K., Aoyagi Y., Nishigaki Y. et al.

Int. J. Mol. Med. 24:233-246(2009) GeneRIF 2997 · Mapped (774)
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) GeneRIF 2997

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