1 - 25 of
62
results
for uniprot:Q99912
in citationmapping
| Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy. Holthe M., Klepstad P., Zahlsen K., Borchgrevink P.C., Hagen L., Dale O., Kaasa S., Krokan H.E., Skorpen F. Eur. J. Clin. Pharmacol. 58:353-356(2002) GAD 137687 GeneRIF 7364 · Mapped (10) |
| Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients. Holthe M., Rakvag T.N., Klepstad P., Idle J.R., Kaasa S., Krokan H.E., Skorpen F. Pharmacogenomics J. 3:17-26(2003) GAD 137685 GeneRIF 7364 · Mapped (4) |
| ABCB1 and cytochrome P450 genotypes and phenotypes: influence on methadone plasma levels and response to treatment. Crettol S., Deglon J.J., Besson J., Croquette-Krokar M., Hammig R., Gothuey I., Monnat M., Eap C.B. Clin. Pharmacol. Ther. 80:668-681(2006) GAD 155004 GeneRIF 7364 · Mapped (71) |
| The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers. Levesque E., Delage R., Benoit-Biancamano M.O., Caron P., Bernard O., Couture F., Guillemette C. Clin. Pharmacol. Ther. 81:392-400(2007) GAD 155007 GeneRIF 7364 · Mapped (15) |
| Sex steroid levels and cortical bone size in young men are associated with a uridine diphosphate glucuronosyltransferase 2B7 polymorphism (H268Y). Swanson C., Lorentzon M., Vandenput L., Labrie F., Rane A., Jakobsson J., Chouinard S., Belanger A., Ohlsson C. J. Clin. Endocrinol. Metab. 92:3697-3704(2007) GAD 155010 GeneRIF 7364 · Mapped (4) |
| Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance. Bhasker C.R., McKinnon W., Stone A., Lo A.C., Kubota T., Ishizaki T., Miners J.O. Pharmacogenetics 10:679-685(2000) GeneRIF 7364 · UniProtKB (1) · Mapped (3) |
| Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7. Antonio L., Xu J., Little J.M., Burchell B., Magdalou J., Radominska-Pandya A. Arch. Biochem. Biophys. 411:251-261(2003) GeneRIF 7364 · Mapped (20) |
| Human uridine diphosphate-glucuronosyltransferase UGT2B7 conjugates mineralocorticoid and glucocorticoid metabolites. Girard C., Barbier O., Veilleux G., El-Alfy M., Belanger A. Endocrinology 144:2659-2668(2003) GeneRIF 7364 · Mapped (4) |
| A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine. Sawyer M.B., Innocenti F., Das S., Cheng C., Ramirez J., Pantle-Fisher F.H., Wright C., Badner J., Pei D., Boyett J.M. et al. Clin. Pharmacol. Ther. 73:566-574(2003) GeneRIF 7364 · Mapped (4) |
| Almokalant glucuronidation in human liver and kidney microsomes: evidence for the involvement of UGT1A9 and 2B7. Gaiser B.K., Lockley D.J., Staines A.G., Baarnhielm C., Burchell B. Xenobiotica 33:1073-1083(2003) GeneRIF 7364 · Mapped (11) |
| Correlation between UDP-glucuronosyltransferase genotypes and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone glucuronidation phenotype in human liver microsomes. Wiener D., Fang J.L., Dossett N., Lazarus P. Cancer Res. 64:1190-1196(2004) GeneRIF 7364 GAD 137688 · Mapped (13) |
| A novel functional polymorphism in the uridine diphosphate-glucuronosyltransferase 2B7 promoter with significant impact on promoter activity. Duguay Y., Baar C., Skorpen F., Guillemette C. Clin. Pharmacol. Ther. 75:223-233(2004) GeneRIF 7364 · Mapped (4) |
| UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients. Sparks R., Ulrich C.M., Bigler J., Tworoger S.S., Yasui Y., Rajan K.B., Porter P., Stanczyk F.Z., Ballard-Barbash R., Yuan X. et al. Breast Cancer Res. 6:R488-98(2004) GeneRIF 7364 · Mapped (20) |
| Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population. Saeki M., Saito Y., Jinno H., Tanaka-Kagawa T., Ohno A., Ozawa S., Ueno K., Kamakura S., Kamatani N., Komamura K. et al. Drug Metab. Dispos. 32:1048-1054(2004) GeneRIF 7364 · Mapped (7) |
| Farnesol is glucuronidated in human liver, kidney and intestine in vitro, and is a novel substrate for UGT2B7 and UGT1A1. Staines A.G., Sindelar P., Coughtrie M.W., Burchell B. Biochem. J. 384:637-645(2004) GeneRIF 7364 · Mapped (10) |
| Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in endometrium. Lepine J., Bernard O., Plante M., Tetu B., Pelletier G., Labrie F., Belanger A., Guillemette C. J. Clin. Endocrinol. Metab. 89:5222-5232(2004) GeneRIF 7364 · Mapped (10) |
| Modulation of UDP-glucuronosyltransferase function by cytochrome P450: evidence for the alteration of UGT2B7-catalyzed glucuronidation of morphine by CYP3A4. Takeda S., Ishii Y., Iwanaga M., Mackenzie P.I., Nagata K., Yamazoe Y., Oguri K., Yamada H. Mol. Pharmacol. 67:665-672(2005) GeneRIF 7364 · Mapped (12) |
| An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China. Lin G.F., Guo W.C., Chen J.G., Qin Y.Q., Golka K., Xiang C.Q., Ma Q.W., Lu D.R., Shen J.H. Toxicol. Sci. 85:502-506(2005) GeneRIF 7364 · Mapped (4) |
| Inhibition of voltage-gated potassium currents by gambierol in mouse taste cells. Ghiaroni V., Sasaki M., Fuwa H., Rossini G.P., Scalera G., Yasumoto T., Pietra P., Bigiani A. Toxicol. Sci. 85:657-665(2005) GeneRIF 7364 · Mapped (4) |
| Clinical response to morphine in cancer patients and genetic variation in candidate genes. Ross J.R., Rutter D., Welsh K., Joel S.P., Goller K., Wells A.U., Du Bois R., Riley J. Pharmacogenomics J. 5:324-336(2005) GeneRIF 7364 · Mapped (33) |
| Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone. Thibaudeau J., Lepine J., Tojcic J., Duguay Y., Pelletier G., Plante M., Brisson J., Tetu B., Jacob S., Perusse L. et al. Cancer Res. 66:125-133(2006) GeneRIF 7364 · Mapped (15) |
| Haplotype analysis of UDP-glucuronocyltransferase 2B7 gene (UGT2B7) polymorphisms in healthy Japanese subjects. Saito K., Moriya H., Sawaguchi T., Hayakawa T., Nakahara S., Goto A., Arimura Y., Imai K., Kurosawa N., Owada E. et al. Clin. Biochem. 39:303-308(2006) GeneRIF 7364 · Mapped (4) |
| Environmental and genetic factors associated with morphine response in the postoperative period. Coulbault L., Beaussier M., Verstuyft C., Weickmans H., Dubert L., Tregouet D., Descot C., Parc Y., Lienhart A., Jaillon P. et al. Clin. Pharmacol. Ther. 79:316-324(2006) GeneRIF 7364 · Mapped (24) |
| Multiple regression analysis of pharmacogenetic variability of carvedilol disposition in 54 healthy Japanese volunteers. Honda M., Ogura Y., Toyoda W., Taguchi M., Nozawa T., Inoue H., Hashimoto Y. Biol. Pharm. Bull. 29:772-778(2006) GeneRIF 7364 · Mapped (54) |
| Contribution of polymorphisms in UDP-glucuronosyltransferase and CYP2D6 to the individual variation in disposition of carvedilol. Takekuma Y., Takenaka T., Kiyokawa M., Yamazaki K., Okamoto H., Kitabatake A., Tsutsui H., Sugawara M. J Pharm Pharm Sci 9:101-112(2006) GeneRIF 7364 GAD 155002 · Mapped (33) |
