uniprot:Q96PG8 in citationmapping

1 - 25 of 43 results for uniprot:Q96PG8 in citationmapping

PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Yu J., Wang Z., Kinzler K.W., Vogelstein B., Zhang L. Proc. Natl. Acad. Sci. U.S.A. 100:1931-1936(2003) GeneRIF 27113 · Mapped (34) role in mediating the apoptotic response to p53 in colorectal cancer cells GeneRIF 27113
PUMA in head and neck cancer. Hoque M.O., Begum S., Sommer M., Lee T., Trink B., Ratovitski E., Sidransky D. Cancer Lett. 199:75-81(2003) GeneRIF 27113 · Mapped (3) PUMA suppresses tumor cell growth in head/neck cancer but it does not appear to be a direct target of inactivation in head and neck tumorigenesis. GeneRIF 27113
Bax conformational change is a crucial step for PUMA-mediated apoptosis in human leukemia. Liu F.T., Newland A.C., Jia L. Biochem. Biophys. Res. Commun. 310:956-962(2003) GeneRIF 27113 · Mapped (9) PUMA-induced Bax conformational change and Bax translocation to mitochondria can be separate events and the conformational change in Bax is crucial for PUMA-induced mitochondrial dysfunction GeneRIF 27113
No PUMA, no death: implications for p53-dependent apoptosis. Yu J., Zhang L. Cancer Cell 4:248-249(2003) GeneRIF 27113 · Mapped (3) PUMA is an essential mediator of p53-dependent and -independent apoptosis in vivo GeneRIF 27113
p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation. Melino G., Bernassola F., Ranalli M., Yee K., Zong W.X., Corazzari M., Knight R.A., Green D.R., Thompson C., Vousden K.H. J. Biol. Chem. 279:8076-8083(2004) GeneRIF 27113 · Mapped (13) findings demonstrate that p73 protein elicits apoptosis via the mitochondrial pathway using p53 up regulated modulator of apoptosis(PUMA) and Bax protein as mediators GeneRIF 27113
HIV: no PUMA no death? Salomoni P., Cossarizza A. Cell Death Differ. 11:691-692(2004) GeneRIF 27113 · Mapped (3) In the absence of PUMA there is no HIV apoptosis. GeneRIF 27113
mRNA and protein expression of PUMA in sporadic colorectal cancer. Jansson A., Arbman G., Sun X.F. Oncol. Rep. 12:1245-1249(2004) GeneRIF 27113 · Mapped (3) PUMA expression may be of minor importance in the development of colorectal cancer GeneRIF 27113
The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA. Cartron P.F., Gallenne T., Bougras G., Gautier F., Manero F., Vusio P., Meflah K., Vallette F.M., Juin P. Mol. Cell 16:807-818(2004) GeneRIF 27113 · Mapped (16) a specific interaction between Bax Halpha1 and their BH3 domains allows Bid and PUMA to function as "death agonists" of Bax GeneRIF 27113
Large-scale quantitative proteomic study of PUMA-induced apoptosis using two-dimensional liquid chromatography-mass spectrometry coupled with amino acid-coded mass tagging. Gu S., Du Y., Chen J., Liu Z., Bradbury E.M., Hu C.A., Chen X. J. Proteome Res. 3:1191-1200(2004) GeneRIF 27113 · Mapped (3) histones and a ubiquitin conjugate protein UBC9 which are involved in DNA double-strand break (DSB) repair were significantly down-regulated in the PUMA-overexpressing apoptotic cells suggesting the detection of DSB in the apoptotic process GeneRIF 27113
Broad degradation of proapoptotic proteins with the conserved Bcl-2 homology domain 3 during infection with Chlamydia trachomatis. Ying S., Seiffert B.M., Hacker G., Fischer S.F. Infect. Immun. 73:1399-1403(2005) GeneRIF 27113 · Mapped (9) degraded during Chlamydia trachomatis infection GeneRIF 27113
Degradation of the proapoptotic proteins Bik, Puma, and Bim with Bcl-2 domain 3 homology in Chlamydia trachomatis-infected cells. Dong F., Pirbhai M., Xiao Y., Zhong Y., Wu Y., Zhong G. Infect. Immun. 73:1861-1864(2005) GeneRIF 27113 · Mapped (8) degraded in Chlamydia trachomatis-infected cells. GeneRIF 27113
Transcriptional upregulation of PUMA modulates endoplasmic reticulum calcium pool depletion-induced apoptosis via Bax activation. Luo X., He Q., Huang Y., Sheikh M.S. Cell Death Differ. 12:1310-1318(2005) GeneRIF 27113 · Mapped (3) Results demonstrate that thapsigargin engages PUMA and Bax for full transduction of apoptotic signals and both PUMA and Bax appear to exist in the same apoptotic pathway in which PUMA may reside upstream of Bax. GeneRIF 27113
*Puma()Mcl-1 interaction is not sufficient to prevent rapid degradation of Mcl-1. Mei Y., Du W., Yang Y., Wu M. Oncogene 24:7224-7237(2005)** GeneRIF 27113 · Mapped (9) The interaction of PUMA with MCL1 is not sufficient to prevent rapid degradation of MCL1. GeneRIF 27113
BBC3 mediates fenretinide-induced cell death in neuroblastoma. Wei J.S., Whiteford C.C., Cenacchi N., Son C.G., Khan J. Oncogene 24:7976-7983(2005) GeneRIF 27113 · Mapped (3) BBC3 mediates fenretinide-induced cell death in neuroblastoma. GeneRIF 27113
PUMA couples the nuclear and cytoplasmic proapoptotic function of p53. Chipuk J.E., Bouchier-Hayes L., Kuwana T., Newmeyer D.D., Green D.R. Science 309:1732-1735(2005) GeneRIF 27113 · Mapped (53) demonstrated that a tripartite nexus between Bcl-xL cytoplasmic p53 and PUMA coordinates the nuclear and cytoplasmic p53 proapoptotic functions GeneRIF 27113
Inhibition of Bax activity is crucial for the antiapoptotic function of the human papillomavirus E6 oncoprotein. Vogt M., Butz K., Dymalla S., Semzow J., Hoppe-Seyler F. Oncogene 25:4009-4015(2006) GeneRIF 27113 · Mapped (40) interference with the p53/PUMA/Bax cascade is crucial for the antiapoptotic function of the viral E6 oncogene in HPV-positive cancer cells GeneRIF 27113
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells. Ming L., Wang P., Bank A., Yu J., Zhang L. J. Biol. Chem. 281:16034-16042(2006) GeneRIF 27113 · Mapped (15) PUMA initiates apoptosis in part by dissociating Bax and Bcl-X(L) thereby promoting Bax multimerization and mitochondrial translocation GeneRIF 27113
Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway. Concannon C.G., Koehler B.F., Reimertz C., Murphy B.M., Bonner C., Thurow N., Ward M.W., Villunger A., Strasser A., Kogel D. et al. Oncogene 26:1681-1692(2007) GeneRIF 27113 · Mapped (34) p53 activation and the transcriptional induction of its target gene PUMA play an important role in the sensitivity of cancer cells to apoptosis induced by proteasome inhibition GeneRIF 27113
Immunohistochemical analysis of pro-apoptotic PUMA protein and mutational analysis of PUMA gene in gastric carcinomas. Yoo N.J., Lee J.W., Jeong E.G., Lee S.H. Dig Liver Dis 39:222-227(2007) GeneRIF 27113 · Mapped (3) Differential expression of PUMA between normal and neoplastic gastric cells suggests that regulation of PUMA expression might play a possible role in the development of gastric adenocarcinoma. GeneRIF 27113
The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage. Wang P., Yu J., Zhang L. Proc. Natl. Acad. Sci. U.S.A. 104:4054-4059(2007) GeneRIF 27113 · Mapped (34) the binding of nuclear p53 to the specific sites within the PUMA promoter is essential for its ability to induce apoptosis and is likely to be required for its tumor suppressive capacity GeneRIF 27113
Involvement of up-regulation of PUMA in non-steroidal anti-inflammatory drug-induced apoptosis. Ishihara T., Hoshino T., Namba T., Tanaka K., Mizushima T. Biochem. Biophys. Res. Commun. 356:711-717(2007) GeneRIF 27113 · Mapped (3) findings suggest that PUMA plays an important role in celecoxib-induced mitochondrial dysfunction and the resulting apoptosis GeneRIF 27113
Pro-apoptotic PUMA and anti-apoptotic phospho-BAD are highly expressed in colorectal carcinomas. Kim M.R., Jeong E.G., Chae B., Lee J.W., Soung Y.H., Nam S.W., Lee J.Y., Yoo N.J., Lee S.H. Dig. Dis. Sci. 52:2751-2756(2007) GeneRIF 27113 · Mapped (6) Expression of BBC3 protein was increased in the colorectal cancer cells and may possibly alter the cell death regulation during colorectal tumorigenesis. GeneRIF 27113
The unhydrolyzable fenretinide analogue 4-hydroxybenzylretinone induces the proapoptotic genes GADD153 (CHOP) and Bcl-2-binding component 3 (PUMA) and apoptosis that is caspase- dependent and independent of the retinoic acid receptor. Anding A.L., Chapman J.S., Barnett D.W., Curley R.W. Jr., Clagett-Dame M. Cancer Res. 67:6270-6277(2007) GeneRIF 27113 · Mapped (5) GADD153 (CHOP) and Bcl-2-binding component 3 (PUMA) and apoptosis are induced by 4-hydroxybenzylretinone in a process that is caspase- dependent and independent of the retinoic acid receptor GeneRIF 27113
Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization. Meng X.W., Lee S.H., Dai H., Loegering D., Yu C., Flatten K., Schneider P., Dai N.T., Kumar S.K., Smith B.D. et al. J. Biol. Chem. 282:29831-29846(2007) GeneRIF 27113 · Mapped (20) Mcl-1 confers TRAIL resistance by serving as a buffer for Bak Bim and Puma and sorafenib is a potential modulator of TRAIL sensitivity GeneRIF 27113
Expressional and mutational analysis of pro-apoptotic Bcl-2 member PUMA in hepatocellular carcinomas. Ahn C.H., Jeong E.G., Kim S.S., Lee J.W., Lee S.H., Kim S.H., Kim M.S., Yoo N.J., Lee S.H. Dig. Dis. Sci. 53:1395-1399(2008) GeneRIF 27113 · Mapped (3) Differential expression of PUMA between non-neoplastic and neoplastic hepatocellular cells suggests that regulation of PUMA expression may play a role in development of hepatocellular carcinoma. GeneRIF 27113