| Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Baranzini S.E., Wang J., Gibson R.A., Galwey N., Naegelin Y., Barkhof F., Radue E.W., Lindberg R.L., Uitdehaag B.M., Johnson M.R. et al.
Hum. Mol. Genet. 18:767-778(2009) GAD 597000 · Mapped (114)
Associated with IMMUNE: normalized brain volume, multiple sclerosis; GAD 597000 |
| BicD-dependent localization processes: from Drosophilia development to human cell biology. Claussen M., Suter B.
Ann. Anat. 187:539-553(2005) GeneRIF 636 · Mapped (3)
Various processes in which BicD is involved during Drosophilian development (review) GeneRIF 636 |
| The Rab6 effector Bicaudal D1 associates with Chlamydia trachomatis inclusions in a biovar-specific manner. Moorhead A.R., Rzomp K.A., Scidmore M.A.
Infect. Immun. 75:781-791(2007) GeneRIF 636 · Mapped (2)
findings show BICD1 localized to Chlamydia trachomatis inclusions in a biovar-specific manner and that EGFP-BICD1 is recruited to the inclusion in a microtubule- and Golgi apparatus-independent but chlamydial gene expression-dependent mechanism GeneRIF 636 |
| GSK-3beta-regulated interaction of BICD with dynein is involved in microtubule anchorage at centrosome. Fumoto K., Hoogenraad C.C., Kikuchi A.
EMBO J. 25:5670-5682(2006) GeneRIF 636 MINT MINT-206187 MINT MINT-206187 MINT MINT-206187 MINT MINT-206187 MINT MINT-206187 MINT MINT-206187 MINT MINT-206187 MINT MINT-206187 MINT MINT-206187 MINT MINT-206187 MINT MINT-206187 MINT MINT-206187 MINT MINT-206187 MINT MINT-206187 MINT MINT-206187 · Mapped (12)
MINT-4049784. GSK3B (uniprotkb:P49841) physically interacts (MI:0915) with BICD1 (uniprotkb:Q96G01) by two hybrid array (MI:0397). From mint MINT MINT-206187 MINT-4049804. BICD1 (uniprotkb:Q96G01) physically interacts (MI:0915) with GSK3B (uniprotkb:P49841) by anti bait coimmunoprecipitation (MI:0006). From mint MINT MINT-206187 MINT-4049823. BICD1 (uniprotkb:Q96G01) binds (MI:0407) to GSK3B (uniprotkb:P49841) by gst pull down (MI:0059). From mint MINT MINT-206187 MINT-4049862. BICD1 (uniprotkb:Q96G01) physically interacts (MI:0915) with GSK3B (uniprotkb:P49841) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-206187 MINT-4049883. BICD1 (uniprotkb:Q96G01) physically interacts (MI:0915) with GSK3B (uniprotkb:P49841) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-206187 MINT-4049907. g-Adaptin (uniprotkb:O43747) and BICD1 (uniprotkb:Q96G01) colocalize (MI:0403) by colocalization by immunostaining (MI:0022). From mint MINT MINT-206187 MINT-4049929. p150Glued (uniprotkb:Q14203) and BICD1 (uniprotkb:Q96G01) colocalize (MI:0403) by colocalization by immunostaining (MI:0022). From mint MINT MINT-206187 MINT-4049943. BICD1 (uniprotkb:Q96G01) physically interacts (MI:0914) with p150Glued (uniprotkb:Q14203) by anti bait coimmunoprecipitation (MI:0006). From mint MINT MINT-206187 MINT-4049943. BICD1 (uniprotkb:Q96G01) physically interacts (MI:0914) with DIC (uniprotkb:O14576) by anti bait coimmunoprecipitation (MI:0006). From mint MINT MINT-206187 MINT-4049943. BICD1 (uniprotkb:Q96G01) physically interacts (MI:0914) with GSK3B (uniprotkb:P49841) by anti bait coimmunoprecipitation (MI:0006). From mint MINT MINT-206187 MINT-4049943. BICD1 (uniprotkb:Q96G01) physically interacts (MI:0914) with p50dynamitin (uniprotkb:Q13561) by anti bait coimmunoprecipitation (MI:0006). From mint MINT MINT-206187 MINT-4049971. BICD1 (uniprotkb:Q96G01) physically interacts (MI:0915) with Ninein (uniprotkb:Q8N4C6) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-206187 MINT-4051287. BICD1 (uniprotkb:Q96G01), GSK3A (uniprotkb:P49840) colocalize (MI:0403) by cosedimentation through density gradient (MI:0029). From mint MINT MINT-206187 MINT-4051287. BICD1 (uniprotkb:Q96G01), GSK3B (uniprotkb:P49841) colocalize (MI:0403) by cosedimentation through density gradient (MI:0029). From mint MINT MINT-206187 MINT-4051287. BICD1 (uniprotkb:Q96G01), TUBG1 (uniprotkb:P23258) colocalize (MI:0403) by cosedimentation through density gradient (MI:0029). From mint MINT MINT-206187 These results imply that GSK-3beta may function in transporting centrosomal proteins to the centrosome by stabilizing the BICD1 and dynein complex resulting in the regulation of a focused microtubule organization. GeneRIF 636 |
| A regulatory SNP of the BICD1 gene contributes to telomere length variation in humans. Mangino M., Brouilette S., Braund P., Tirmizi N., Vasa-Nicotera M., Thompson J.R., Samani N.J.
Hum. Mol. Genet. 17:2518-2523(2008) GeneRIF 636 · Mapped (2)
BICD1 plays a similar role in telomere length homeostasis in humans. GeneRIF 636 |
| Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. Xu J., Zheng S.L., Isaacs S.D., Wiley K.E., Wiklund F., Sun J., Kader A.K., Li G., Purcell L.D., Kim S.T. et al.
Proc. Natl. Acad. Sci. U.S.A. 107:2136-2140(2010) GeneRIF 636 · Mapped (105)
Observational study of gene-disease association. (HuGE Navigator) GeneRIF 636 |
| A novel protease-activated receptor-1 interactor, Bicaudal D1, regulates G protein signaling and internalization. Swift S., Xu J., Trivedi V., Austin K.M., Tressel S.L., Zhang L., Covic L., Kuliopulos A.
J. Biol. Chem. 285:11402-11410(2010) GeneRIF 636 · Mapped (16)
the protease-activated receptor-1 interactor Bicaudal D1 regulates G protein signaling and internalization GeneRIF 636 |
| Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose J.E., Behm F.M., Drgon T., Johnson C., Uhl G.R.
Mol. Med. 16:247-253(2010) GeneRIF 636 · Mapped (10,283)
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) GeneRIF 636 |
| Genome-wide association study of pancreatic cancer in Japanese population. Low S.K., Kuchiba A., Zembutsu H., Saito A., Takahashi A., Kubo M., Daigo Y., Kamatani N., Chiku S., Totsuka H. et al.
PLoS ONE 5:e11824-e11824(2010) GeneRIF 636 · Mapped (12)
Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) GeneRIF 636 |
| Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema. Kong X., Cho M.H., Anderson W., Coxson H.O., Muller N., Washko G., Hoffman E.A., Bakke P., Gulsvik A., Lomas D.A. et al.
Am. J. Respir. Crit. Care Med. 183:43-49(2011) GeneRIF 636 · Mapped (2)
Variants in BICD1 are associated with length of telomeres which suggests that a mechanism linked to accelerated aging may be involved in the pathogenesis of emphysema; Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) GeneRIF 636 |
