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SPAM1 (PH-20) protein and mRNA expression in the epididymides of humans and macaques: utilizing laser microdissection/RT-PCR.

Evans E.A., Zhang H., Martin-DeLeon P.A.

Reprod. Biol. Endocrinol. 1:54-54(2003) GeneRIF 6677 · Mapped (3)
SPAM1 mRNA & protein occur in all 3 regions of epididymis & vas deferens. It has hyaluronidase activity at pH 7.0. The proximal promoter has epididymal transcription factor sites including androgen receptor elements. Its role may be in sperm maturation. GeneRIF 6677

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