Tani K., Sato S., Sukezane T., Kojima H., Hirose H., Hanafusa H., Shishido T.

J. Biol. Chem. 278:21685-21692(2003) GeneRIF 55740 · UniProtKB (3) · Mapped (47)
mena phosphorylation is regulated by Abi-1 and c-Abl GeneRIF 55740

Di Modugno F., Mottolese M., Di Benedetto A., Conidi A., Novelli F., Perracchio L., Venturo I., Botti C., Jager E., Santoni A. et al.

Clin. Cancer Res. 12:1470-1478(2006) GeneRIF 55740 · Mapped (5)
overexpression of ENAH is associated with breast cancer GeneRIF 55740

Pino M.S., Balsamo M., Di Modugno F., Mottolese M., Alessio M., Melucci E., Milella M., McConkey D.J., Philippar U., Gertler F.B. et al.

Clin. Cancer Res. 14:4943-4950(2008) GeneRIF 55740 · Mapped (24)
the hMena(+11a) isoform is associated with an epithelial phenotype and identifies EGFR-dependent cell lines that are sensitive to the EGFR inhibitor erlotinib GeneRIF 55740

Goswami S., Philippar U., Sun D., Patsialou A., Avraham J., Wang W., Di Modugno F., Nistico P., Gertler F.B., Condeelis J.S.

Clin. Exp. Metastasis 26:153-159(2009) GeneRIF 55740 · Mapped (5)
two isoforms of Mena ++ and +++ are upregulated in the invasive tumor cells and one isoform 11a is downregulated GeneRIF 55740

Philippar U., Roussos E.T., Oser M., Yamaguchi H., Kim H.D., Giampieri S., Wang Y., Goswami S., Wyckoff J.B., Lauffenburger D.A. et al.

Dev. Cell 15:813-828(2008) GeneRIF 55740 · Mapped (15)
the Mena invasion isoform potentiates EGF-induced carcinoma cell invasion and metastasis GeneRIF 55740

Toyoda A., Kawana H., Azuhata K., Yu J., Omata A., Kishi H., Higashi M., Harigaya K.

Int. J. Oncol. 34:53-60(2009) GeneRIF 55740 · Mapped (5)
Increased hMena expression is associated with colorectal carcinomas. GeneRIF 55740

Higashi M., Ishikawa C., Yu J., Toyoda A., Kawana H., Kurokawa K., Matsuda M., Kitagawa M., Harigaya K.

PLoS ONE 4:e4765-e4765(2009) GeneRIF 55740 · Mapped (5)
hMena possesses properties which help to regulate the formation of lamellipodia through the modulation of the activity of Rac1. GeneRIF 55740

Gurzu S., Jung I., Prantner I., Chira L., Ember I.

Rom J Morphol Embryol 50:213-216(2009) GeneRIF 55740 · Mapped (5)
Mena was not expressed in the normal cervical squamous epithelium but its expression was increased in parallel with the increasing grade of CIN with up-regulation upon transition to CIN3 and further to invasive carcinoma. GeneRIF 55740

Hahn W.H., Suh J.S., Cho B.S., Kim S.D.

Exp. Mol. Med. 41:793-801(2009) GeneRIF 55740 · Mapped (5)
Observational study of gene-disease association. (HuGE Navigator); ENAH polymorphisms are associated with increased susceptibility development of proteinuria and gross hematuria and pathological progression of childhood IgAN. GeneRIF 55740

Chattopadhyay I., Singh A., Phukan R., Purkayastha J., Kataki A., Mahanta J., Saxena S., Kapur S.

Mutat. Res. 696:130-138(2010) GeneRIF 55740 · Mapped (103)
Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) GeneRIF 55740

Rose J.E., Behm F.M., Drgon T., Johnson C., Uhl G.R.

Mol. Med. 16:247-253(2010) GeneRIF 55740 · Mapped (10,283)
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) GeneRIF 55740

Di Modugno F., Mottolese M., DeMonte L., Trono P., Balsamo M., Conidi A., Melucci E., Terrenato I., Belleudi F., Torrisi M.R. et al.

PLoS ONE 5:e15852-e15852(2010) GeneRIF 55740 · Mapped (13)
hMena and HER2 signalling has a role in breast cancer GeneRIF 55740

Aguilar F., Belmonte S.L., Ram R., Noujaim S.F., Dunaevsky O., Protack T.L., Jalife J., Todd Massey H., Gertler F.B., Blaxall B.C.

Am. J. Physiol. Heart Circ. Physiol. 300:H1841-52(2011) GeneRIF 55740 · Mapped (10)
Mammalian enabled (Mena) is a critical regulator of cardiac function. GeneRIF 55740

Takaku M., Ueno H., Kurumizaka H.

J. Biochem. 149:721-729(2011) GeneRIF 55740 · Mapped (9)
ENA/VASP-family proteins are functionally redundant in homologous recombination and MENA VASP and EVL may be involved in the DSB repair pathway in humans GeneRIF 55740

Lara R., Mauri F.A., Taylor H., Derua R., Shia A., Gray C., Nicols A., Shiner R.J., Schofield E., Bates P.A. et al.

Oncogene 30:3513-3521(2011) GeneRIF 55740 · Mapped (7)
Data show that VASP and Mena interact with RSK1. GeneRIF 55740

Takahashi K., Suzuki K.

J. Cell. Biochem. 112:3421-3429(2011) GeneRIF 55740 · Mapped (9)
results indicate that by mediating intensive F-actin accumulation at the sites of cell infiltration WAVE2 N-WASP and Mena are crucial for PI3K-dependent cell invasion induced by PDGF GeneRIF 55740

Gurzu S., Krause M., Ember I., Azamfirei L., Gobel G., Feher K., Jung I.

Eur J Histochem 56:e8-e8(2012) GeneRIF 55740 · Mapped (5)
Mena protein seems to play a role in malignant transformation and its intensity is correlated with the type and grade of tumor and also with vascular invasion. Its positivity in endothelial cells may suggest its potential role in tumor angiogenesis. GeneRIF 55740

Najafov A., Seker T., Even I., Hoxhaj G., Selvi O., Ozel D.E., Koman A., Birgul-Iyison N.

PLoS ONE 7:e37013-e37013(2012) GeneRIF 55740 · Mapped (5)
Overexpression of Wnt1 and Wnt3a ligands increased MENA mRNA levels. GeneRIF 55740

Di Modugno F., Iapicca P., Boudreau A., Mottolese M., Terrenato I., Perracchio L., Carstens R.P., Santoni A., Bissell M.J., Nistico P.

Proc. Natl. Acad. Sci. U.S.A. 109:19280-19285(2012) GeneRIF 55740 · UniProtKB (1) · Mapped (4)
These data suggest that polarized and growth-arrested cellular architecture correlates with absence of alternative hMENA isoform expression. GeneRIF 55740

Schreiner D., Muller K., Hofer H.W.

FEBS Lett. 580:5295-5300(2006) MINT MINT-3041121 MINT MINT-3041121 · Mapped (13)
MINT-3370478. ENAH (uniprotkb:Q8N8S7) binds (MI:0407) to FAT1 (uniprotkb:Q14517) by enzyme linked immunosorbent assay (MI:0411). From mint MINT MINT-3041121 MINT-3370511. ENAH (uniprotkb:Q8N8S7) binds (MI:0407) to FAT1 (uniprotkb:Q14517) by enzyme linked immunosorbent assay (MI:0411). From mint MINT MINT-3041121