Pan J.L., Xue Y.Q., Jiang H.Y., He J., Wang W., Wu Y.F.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 22:444-446(2005) GeneRIF 4300 · Mapped (15)
In the Acute Myeloid Leukemia patients detected MLL rearrangements consisting of MLL/AF6 MLL/AF9 MLL/AF17 MLL/ELL and MLL partial tandem duplication. MLL rearrangement include chromosome translocation and partial tandem duplication. GeneRIF 4300

He J., Chen Z.X., Xue Y.Q., Li J.Q., He H.L., Huang Y.P., He Y.X., Chai Y.H., Zhu L.L.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 22:551-553(2005) GeneRIF 4300 · Mapped (34)
The patients with immunophenotype of Pre-B-acute lymphoblastic leukemia were found to carry: MLL/AF9. GeneRIF 4300

Martino V., Tonelli R., Montemurro L., Franzoni M., Marino F., Fazzina R., Pession A.

Oncol. Rep. 15:207-211(2006) GeneRIF 4300 · Mapped (15)
Down-regulation of AF9 is not necessary to abolish malignant phenotypes by induction of terminal monocyte-macrophage differentiation in leukaemic cells carrying t(9;11)(p22;q23). GeneRIF 4300

Nakamura T., Canaani E., Croce C.M.

Proc. Natl. Acad. Sci. U.S.A. 104:10980-10985(2007) GeneRIF 4300 · Mapped (21)
demonstrate coimmunoprecipitation of the All1/Af4 and All1/Af9 fusions with Drosha disrupted by treatment with DNase I GeneRIF 4300

Pina C., May G., Soneji S., Hong D., Enver T.

Cell Stem Cell 2:264-273(2008) GeneRIF 4300 · Mapped (8)
MLLT3 as a regulator of early erythroid and megakaryocytic cell fate in the human system. GeneRIF 4300

Wei J., Wunderlich M., Fox C., Alvarez S., Cigudosa J.C., Wilhelm J.S., Zheng Y., Cancelas J.A., Gu Y., Jansen M. et al.

Cancer Cell 13:483-495(2008) GeneRIF 4300 · Mapped (8)
Expression of MLL-AF9 in human CD34+ cells induces acute myeloid lymphoid or mixed-lineage leukemia in immunodeficient mice. GeneRIF 4300

Haribaskar R., Putz M., Schupp B., Skouloudaki K., Bietenbeck A., Walz G., Schafer T.

Biochem. Biophys. Res. Commun. 387:212-217(2009) GeneRIF 4300 · Mapped (22)
Diversin containing several nuclear localization signals translocates to the nucleus where it interacts with the transcription factor AF9. GeneRIF 4300

Reisenauer M.R., Anderson M., Huang L., Zhang Z., Zhou Q., Kone B.C., Morris A.P., Lesage G.D., Dryer S.E., Zhang W.

J. Biol. Chem. 284:35659-35669(2009) GeneRIF 4300 · Mapped (26)
AF17 competes with AF9 to bind Dot1a decreases Dot1a nuclear expression by possibly facilitating its nuclear export and relieves Dot1a.AF9-mediated repression of alpha-ENaC and other target genes. GeneRIF 4300

Rose J.E., Behm F.M., Drgon T., Johnson C., Uhl G.R.

Mol. Med. 16:247-253(2010) GeneRIF 4300 · Mapped (10,283)
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) GeneRIF 4300

Chandra P., Luthra R., Zuo Z., Yao H., Ravandi F., Reddy N., Garcia-Manero G., Kantarjian H., Jones D.

Am. J. Clin. Pathol. 133:686-693(2010) GeneRIF 4300 · Mapped (8)
Ras activation seems to complement the MLLT3-MLL oncogene in transformation. GeneRIF 4300

Wang X., Chorley B.N., Pittman G.S., Kleeberger S.R., Brothers J., Liu G., Spira A., Bell D.A.

PLoS ONE 5:e11934-e11934(2010) GeneRIF 4300 · Mapped (124)
Observational study of gene-disease association. (HuGE Navigator) GeneRIF 4300

Zhan L., Kerr J.R., Lafuente M.J., Maclean A., Chibalina M.V., Liu B., Burke B., Bevan S., Nasir J.

Neuropathol. Appl. Neurobiol. 37:206-219(2011) GeneRIF 4300 · Mapped (22)
our data suggest: (i) C14ORF28 GNB2L1 MLLT3 DRD2 and DARPP-32 are important in the pathogenesis of schizophrenia and bipolar disorder GeneRIF 4300

Noordermeer S.M., Sanders M.A., Gilissen C., Tonnissen E., van der Heijden A., Dohner K., Bullinger L., Jansen J.H., Valk P.J., van der Reijden B.A.

Blood 118:5613-5621(2011) GeneRIF 4300 · Mapped (10)
Within the group of MLL-AF9-positive patients high BRE expression predicted superior survival while normal BRE expression predicted extremely poor survival. GeneRIF 4300

Muller-Schmah C., Solari L., Weis R., Pfeifer D., Scheibenbogen C., Trepel M., May A.M., Engelhardt R., Lubbert M.

Ann. Hematol. 91:27-32(2012) GeneRIF 4300 · Mapped (8)
MLL-AF9-negative U937 cells but not positive MLL-AF9 THP-1 cells suggesting that the toxocity ting was not antibody-mediated by antibodies against MLL-AF9 protein. GeneRIF 4300

Lee S.T., Ji Y., Kim H.J., Ki C.S., Jung C.W., Kim J.W., Kim S.H.

Leuk. Res. 36:418-421(2012) GeneRIF 4300 · Mapped (29)
we identified a novel fusion gene consisted of PAX5 and MLLT3 during progression from chronic phase to blastic phase in chronic myeloid leukemia GeneRIF 4300

Bergerson R.J., Collier L.S., Sarver A.L., Been R.A., Lugthart S., Diers M.D., Zuber J., Rappaport A.R., Nixon M.J., Silverstein K.A. et al.

Blood 119:4512-4523(2012) GeneRIF 4300 · Mapped (12)
Identification of genes that define transcription factor networks and important genetic pathways acting during progression of leukemia induced by MLL fusion oncogenes. GeneRIF 4300