uniprot:Q80Y89 in citationmapping

1 - 25 of 98 results for uniprot:Q80Y89 in citationmapping

Centrosome abnormalities, recurring deletions of chromosome 4, and genomic amplification of HER2/neu define mouse mammary gland adenocarcinomas induced by mutant HER2/neu. Montagna C., Andrechek E.R., Padilla-Nash H., Muller W.J., Ried T. Oncogene 21:890-898(2002) GeneRIF 13866 · Mapped (6) conditional expression of activated HER2/neu gene under its endogenous promoter in the mammary epithelium of the mouse resluts in accelerated lobular development and focal mammary tumors. GeneRIF 13866
ErbB2/Neu-induced, cyclin D1-dependent transformation is accelerated in p27-haploinsufficient mammary epithelial cells but impaired in p27-null cells. Muraoka R.S., Lenferink A.E., Law B., Hamilton E., Brantley D.M., Roebuck L.R., Arteaga C.L. Mol. Cell. Biol. 22:2204-2219(2002) GeneRIF 13866 · Mapped (16) ErbB2/Neu-induced cyclin D1-dependent transformation is accelerated in p27-haploinsufficient mammary epithelial cells but impaired in p27-null cells GeneRIF 13866
ErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu transgenic carcinomas. Schroeder J.A., Adriance M.C., McConnell E.J., Thompson M.C., Pockaj B., Gendler S.J. J. Biol. Chem. 277:22692-22698(2002) GeneRIF 13866 · Mapped (23) ErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu transgenic carcinomas. GeneRIF 13866
ErbB2 activation of ESX gene expression. Neve R.M., Ylstra B., Chang C.-H., Albertson D.G., Benz C.C. Oncogene 21:3934-3938(2002) GeneRIF 13866 · UniProtKB (1) · Mapped (16) ErbB2 activation of ESX gene expression GeneRIF 13866
ErbB2 is required for muscle spindle and myoblast cell survival. Andrechek E.R., Hardy W.R., Girgis-Gabardo A.A., Perry R.L., Butler R., Graham F.L., Kahn R.C., Rudnicki M.A., Muller W.J. Mol. Cell. Biol. 22:4714-4722(2002) GeneRIF 13866 · Mapped (6) ErbB2 is required for muscle spindle and myoblast cell survival (receptor ERBB-2) GeneRIF 13866
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy. Ozcelik C., Erdmann B., Pilz B., Wettschureck N., Britsch S., Hubner N., Chien K.R., Birchmeier C., Garratt A.N. Proc. Natl. Acad. Sci. U.S.A. 99:8880-8885(2002) GeneRIF 13866 · Mapped (8) mutation leads to dilated cardiomyopathy GeneRIF 13866
Heart-valve mesenchyme formation is dependent on hyaluronan-augmented activation of ErbB2-ErbB3 receptors. Camenisch T.D., Schroeder J.A., Bradley J., Klewer S.E., McDonald J.A. Nat. Med. 8:850-855(2002) GeneRIF 13866 · Mapped (6) data provide a link between extracellular matrix-hyaluronan and ErbB receptor activation during development of early heart-valve and septal mesenchyme GeneRIF 13866
Oncogenic Ras/Her-2 mediate hyperproliferation of polarized epithelial cells in 3D cultures and rapid tumor growth via the PI3K pathway. Janda E., Litos G., Grunert S., Downward J., Beug H. Oncogene 21:5148-5159(2002) GeneRIF 13866 · Mapped (6) Oncogenic Ras/Her-2 mediate hyperproliferation of polarized epithelial cells in 3D cultures and rapid tumor growth via the PI3K pathway. GeneRIF 13866
ErbB-2-induced mammary tumor growth: the role of cyclin D1 and p27Kip1. Hulit J., Lee R.J., Russell R.G., Pestell R.G. Biochem. Pharmacol. 64:827-836(2002) GeneRIF 13866 · Mapped (16) a key role for components of the cell-cycle in particular cyclin D1 and p27Kip1 (p27) in the onset and progression of ErbB-2-induced murine mammary tumorigenesis. GeneRIF 13866
Colonic epithelial expression of ErbB2 is required for postnatal maintenance of the enteric nervous system. Crone S.A., Negro A., Trumpp A., Giovannini M., Lee K.F. Neuron 37:29-40(2003) GeneRIF 13866 · Mapped (6) ErbB2 signaling in the colonic epithelia is required for the postnatal survival of enteric neurons and glia. GeneRIF 13866
Tyrosine phosphatase-epsilon activates Src and supports the transformed phenotype of Neu-induced mammary tumor cells. Gil-Henn H., Elson A. J. Biol. Chem. 278:15579-15586(2003) GeneRIF 13866 · UniProtKB (1) · Mapped (10) RPTPepsilon is a physiological activator of Src in Neu-induced mammary tumors. GeneRIF 13866
Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function. Iwamoto R., Yamazaki S., Asakura M., Takashima S., Hasuwa H., Miyado K., Adachi S., Kitakaze M., Hashimoto K., Raab G. et al. Proc. Natl. Acad. Sci. U.S.A. 100:3221-3226(2003) GeneRIF 13866 · Mapped (23) HB-EGF induced tyrosine phosphorylation of ErbB2 and ErbB4 and to a lesser degree of EGFR in cardiac myocytes. GeneRIF 13866
Neuregulin 1-erbB2 signaling is required for the establishment of radial glia and their transformation into astrocytes in cerebral cortex. Schmid R.S., McGrath B., Berechid B.E., Boyles B., Marchionni M., Sestan N., Anton E.S. Proc. Natl. Acad. Sci. U.S.A. 100:4251-4256(2003) GeneRIF 13866 · Mapped (14) interaction of this protein with neuregulin 1 signaling is required for the establishment of radial glia and their transformation into astrocytes in cerebral cortex. GeneRIF 13866
Erbb2 regulates neuromuscular synapse formation and is essential for muscle spindle development. Leu M., Bellmunt E., Schwander M., Farinas I., Brenner H.R., Muller U. Development 130:2291-2301(2003) GeneRIF 13866 · Mapped (17) Erbb2 signaling regulates the formation of both neuromuscular synapses and muscle spindles. GeneRIF 13866
Characterization and chromosomal instability of novel derived cell lines from a wt-erbB-2 transgenic mouse model. Jeruss J.S., Liu N.X., Chung Y., Magrane G., Waldman F., Edgerton S., Yang X., Thor A.D. Carcinogenesis 24:659-664(2003) GeneRIF 13866 · Mapped (6) examination of role in choromosomal instability leading to mammary tumorigenesis GeneRIF 13866
The role of ErbB2 signaling in the onset of terminal differentiation of oligodendrocytes in vivo. Kim J.Y., Sun Q., Oglesbee M., Yoon S.O. J. Neurosci. 23:5561-5571(2003) GeneRIF 13866 · Mapped (6) For oligodendrocyte progenitors ErbB2 signaling plays a role in governing a properly timed exit from the cell cycle during development into myelinating oligodendrocytes GeneRIF 13866
Role of extracellular subdomains of p185c-neu and the epidermal growth factor receptor in ligand-independent association and transactivation. Kumagai T., Katsumata M., Hasegawa A., Furuuchi K., Funakoshi T., Kawase I., Greene M.I. Proc. Natl. Acad. Sci. U.S.A. 100:9220-9225(2003) GeneRIF 13866 · Mapped (6) cysteine-rich domains of p185c-neu have roles in assembly and transactivation of erbB complexes GeneRIF 13866
Mammary tumors in HER-2/NEU mice are characterized by low content of estrogen receptors-alpha and absence of progesterone receptors. Bershtein L.M., Alimova I.N., Tsyrlina E.V., Anisimov V.N. Bull. Exp. Biol. Med. 135:580-581(2003) GeneRIF 13866 · Mapped (12) Results suggest that adenocarcinomas in HER-2/neu mice are characterized by relative dependence on estrogen recptors because they lack prolactin receptors. GeneRIF 13866
Increased malignancy of Neu-induced mammary tumors overexpressing active transforming growth factor beta1. Muraoka R.S., Koh Y., Roebuck L.R., Sanders M.E., Brantley-Sieders D., Gorska A.E., Moses H.L., Arteaga C.L. Mol. Cell. Biol. 23:8691-8703(2003) GeneRIF 13866 · Mapped (6) Neu does not abrogate TGF-beta-mediated antiproliferative action but can synergize with TGF-beta in accelerating metastatic mammary tumor progression. GeneRIF 13866
Negative regulation of HER2 signaling by the PEST-type protein-tyrosine phosphatase BDP1. Gensler M., Buschbeck M., Ullrich A. J. Biol. Chem. 279:12110-12116(2004) GeneRIF 13866 · Mapped (21) HER2 signaling is negatively regulated by the PEST-type protein-tyrosine phosphatase BDP1 GeneRIF 13866
Epidermal growth factor receptor-dependent activation of Gab1 is involved in ErbB-2-mediated mammary tumor progression. Gillgrass A., Cardiff R.D., Sharan N., Kannan S., Muller W.J. Oncogene 22:9151-9155(2003) GeneRIF 13866 · Mapped (18) ERBB-2-induced mammary tumor progression requires EGFR-dependent activation of Gab1. GeneRIF 13866
Ligand-induced, p38-dependent apoptosis in cells expressing high levels of epidermal growth factor receptor and ErbB-2. Tikhomirov O., Carpenter G. J. Biol. Chem. 279:12988-12996(2004) GeneRIF 13866 · Mapped (39) EGFR and ErbB-2 have roles in ligand-dependent apoptosis that could be a natural mechanism to protect tissues from unrestricted proliferation GeneRIF 13866
HER-2/neu-mediated regulation of components of the MHC class I antigen-processing pathway. Herrmann F., Lehr H.A., Drexler I., Sutter G., Hengstler J., Wollscheid U., Seliger B. Cancer Res. 64:215-220(2004) GeneRIF 13866 · Mapped (6) HER-2/neu overexpression may influence the design of HER-2/neu-targeted T-cell-based immunotherapeutic strategies. GeneRIF 13866
Upregulation of IKKalpha/IKKbeta by integrin-linked kinase is required for HER2/neu-induced NF-kappaB antiapoptotic pathway. Makino K., Day C.P., Wang S.C., Li Y.M., Hung M.C. Oncogene 23:3883-3887(2004) GeneRIF 13866 · Mapped (21) upregulation of IKKalpha and IKKbeta by the ILK/Akt pathway is required for the HER2/neu-mediated NF-kappaB antiapoptotic pathway. GeneRIF 13866
Germ-line expression of an oncogenic erbB2 allele confers resistance to erbB2-induced mammary tumorigenesis. Andrechek E.R., Hardy W.R., Laing M.A., Muller W.J. Proc. Natl. Acad. Sci. U.S.A. 101:4984-4989(2004) GeneRIF 13866 · Mapped (7) observations suggest that the temporal pattern of expression of activated ErbB2 is a critical determinant in mammary tumorigenesis GeneRIF 13866