uniprot:Q6PDM6 in citationmapping

18 results for uniprot:Q6PDM6 in citationmapping

Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activation. Rossman K.L., Cheng L., Mahon G.M., Rojas R.J., Snyder J.T., Whitehead I.P., Sondek J. J. Biol. Chem. 278:18393-18400(2003) GeneRIF 17207 MGI 103263 · Mapped (13) the PH domain of Dbs has a role in regulating Rho GTPase activation GeneRIF 17207
Critical role of the pleckstrin homology domain in Dbs signaling and growth regulation. Fuentes E.J., Karnoub A.E., Booden M.A., Der C.J., Campbell S.L. J. Biol. Chem. 278:21188-21196(2003) GeneRIF 17207 · Mapped (10) the PH domain of Dbs has two roles in the regulation of DH domain function one for GTPase association and activation in vitro and one for phosphoinositide binding and GTPase interaction in vivo that together promote Dbs association with membranes. GeneRIF 17207
Pleckstrin homology domain-mediated activation of the rho-specific guanine nucleotide exchange factor Dbs by Rac1. Cheng L., Mahon G.M., Kostenko E.V., Whitehead I.P. J. Biol. Chem. 279:12786-12793(2004) GeneRIF 17207 · Mapped (32) Dbs is activated by Rac1 at the pleckstrin homology domain GeneRIF 17207
The RhoA- and CDC42-specific exchange factor Dbs promotes expansion of immature thymocytes and deletion of double-positive and single-positive thymocytes. Klinger M.B., Guilbault B., Kay R.J. Eur. J. Immunol. 34:806-816(2004) GeneRIF 17207 · Mapped (10) Dbs has the potential to promote proliferation of immature thymocytes but also sensitizes immature thymocytes to deletion. GeneRIF 17207
Crystal structure of the DH/PH fragment of Dbs without bound GTPase. Worthylake D.K., Rossman K.L., Sondek J. Structure 12:1078-1086(2004) GeneRIF 17207 PDB 1RJ2 · Mapped (11) Crystal structure of the DH/PH fragment of Dbs without bound GTPase GeneRIF 17207
The Sec14 homology domain regulates the cellular distribution and transforming activity of the Rho-specific guanine nucleotide exchange factor Dbs. Kostenko E.V., Mahon G.M., Cheng L., Whitehead I.P. J. Biol. Chem. 280:2807-2817(2005) GeneRIF 17207 · Mapped (16) the Sec14 domain regulates Dbs transformation through at least two distinct mechanisms neither of which appears to directly influence the in vivo exchange activity of the protein GeneRIF 17207
Functional annotation of a full-length mouse cDNA collection. Kawai J., Shinagawa A., Shibata K., Yoshino M., Itoh M., Ishii Y., Arakawa T., Hara A., Fukunishi Y., Konno H. et al. Nature 409:685-690(2001) MGI 103263 · UniProtKB (17,869) · Mapped (14,263)
A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange. Rossman K.L., Worthylake D.K., Snyder J.T., Siderovski D.P., Campbell S.L., Sondek J. EMBO J. 21:1315-1326(2002) MGI 103263 · UniProtKB (1) · Mapped (9)
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y., Furuno M., Kasukawa T., Adachi J., Bono H., Kondo S., Nikaido I., Osato N., Saito R., Suzuki H. et al. Nature 420:563-573(2002) MGI 103263 · UniProtKB (17,872) · Mapped (20,305)
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D., Kawamoto M., Huang C.C., Johns S.J., King L.A., Harper C.A., Meng E.C., Lee R.E., Yee A., L'Italien L. et al. Nucleic Acids Res. 31:278-281(2003) MGI 103263 · Mapped (10,878)
Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N., Kikuno R., Ohara R., Inamoto S., Aizawa H., Yuasa S., Nakajima D., Nagase T., Ohara O., Koga H. DNA Res. 10:35-48(2003) MGI 103263 · UniProtKB (391) · Mapped (724)
Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain. Yoshizawa M., Sone M., Matsuo N., Nagase T., Ohara O., Nabeshima Y., Hoshino M. Gene Expr. Patterns 3:375-381(2003) MGI 103263 · Mapped (41)
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz B.P., Abuin A., Ramirez-Solis R., Richter L.J., Piggott J., BeltrandelRio H., Buxton E.C., Edwards J., Finch R.A., Friddle C.J. et al. Proc. Natl. Acad. Sci. U.S.A. 100:14109-14114(2003) MGI 103263 · Mapped (23,055)
Genomic analysis of mouse retinal development. Blackshaw S., Harpavat S., Trimarchi J., Cai L., Huang H., Kuo W.P., Weber G., Lee K., Fraioli R.E., Cho S.-H. et al. PLoS Biol. 2:1411-1431(2004) MGI 103263 · UniProtKB (1) · Mapped (2,777)
The transcriptional landscape of the mammalian genome. Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C. et al. Science 309:1559-1563(2005) MGI 103263 · UniProtKB (27,424) · Mapped (12,732)
Transformation by the Rho-specific guanine nucleotide exchange factor Dbs requires ROCK I-mediated phosphorylation of myosin light chain. Liu Z., Kostenko E.V., Mahon G.M., Olabisi O.O., Whitehead I.P. J. Biol. Chem. 281:16043-16051(2006) MGI 103263 GeneRIF 17207 · Mapped (13) Dbs transformation is associated with increased phosphorylation of myosin light chain and stress fiber formation both of which occur in a ROCK-dependent manner GeneRIF 17207
The Dbs PH domain contributes independently to membrane targeting and regulation of guanine nucleotide-exchange activity. Baumeister M.A., Rossman K.L., Sondek J., Lemmon M.A. Biochem. J. 400:563-572(2006) MGI 103263 · Mapped (7)
Retroviral transduction and oncogenic selection of a cDNA encoding Dbs, a homolog of the Dbl guanine nucleotide exchange factor. Whitehead I., Kirk H., Kay R. Oncogene 10:713-721(1995) MGI 103263 · UniProtKB (1) · Mapped (6)