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1 - 25 of 32 results for uniprot:Q53FN0 in Computationally mapped citations

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Exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer-bound SR proteins.

Zhu J., Mayeda A., Krainer A.R.

Mol. Cell 8:1351-1361(2001) GeneRIF 6427 · Mapped (23)
exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer-bound SR proteins GeneRIF 6427

Roles of hnRNP A1, SR proteins, and p68 helicase in c-H-ras alternative splicing regulation.

Guil S., Gattoni R., Carrascal M., Abian J., Stevenin J., Bach-Elias M.

Mol. Cell. Biol. 23:2927-2941(2003) GeneRIF 6427 · Mapped (30)
role in c-H-ras alternative splicing regulation GeneRIF 6427

Nuclear speckle localisation of the small heat shock protein alpha B-crystallin and its inhibition by the R120G cardiomyopathy-linked mutation.

van den IJssel P., Wheelock R., Prescott A., Russell P., Quinlan R.A.

Exp. Cell Res. 287:249-261(2003) GeneRIF 6427 · Mapped (25)
CRYAB was preferentially localized to nuclear speckles as shown by colocalization with SC35. GeneRIF 6427

SC35 and heterogeneous nuclear ribonucleoprotein A/B proteins bind to a juxtaposed exonic splicing enhancer/exonic splicing silencer element to regulate HIV-1 tat exon 2 splicing.

Zahler A.M., Damgaard C.K., Kjems J., Caputi M.

J. Biol. Chem. 279:10077-10084(2004) GeneRIF 6427 · Mapped (18)
hnRNP A1 binding to the exonic splicing silencer element inhibits splicing of the upstream intron by directly masking the SC35 binding site GeneRIF 6427

Differential effects of the SR proteins 9G8, SC35, ASF/SF2, and SRp40 on the utilization of the A1 to A5 splicing sites of HIV-1 RNA.

Ropers D., Ayadi L., Gattoni R., Jacquenet S., Damier L., Branlant C., Stevenin J.

J. Biol. Chem. 279:29963-29973(2004) GeneRIF 6427 · Mapped (22)
SR proteins 9G8 SC35 ASF/SF2 and SRp40 have effects on the utilization of the A1 to A5 splicing sites of HIV-1 RNA GeneRIF 6427

hnRNP A1 and the SR proteins ASF/SF2 and SC35 have antagonistic functions in splicing of beta-tropomyosin exon 6B.

Expert-Bezancon A., Sureau A., Durosay P., Salesse R., Groeneveld H., Lecaer J.P., Marie J.

J. Biol. Chem. 279:38249-38259(2004) GeneRIF 6427 · Mapped (23)
hnRNP A1 and ASF/SF2 and SC35 have antagonistic roles in splicing of beta-tropomyosin exon 6B GeneRIF 6427

Mimicking phosphorylation of the small heat-shock protein alphaB-crystallin recruits the F-box protein FBX4 to nuclear SC35 speckles.

den Engelsman J., Bennink E.J., Doerwald L., Onnekink C., Wunderink L., Andley U.P., Kato K., de Jong W.W., Boelens W.C.

Eur. J. Biochem. 271:4195-4203(2004) GeneRIF 6427 · Mapped (13)
alphaB-crystallin has a phosphorylation-dependent role in the ubiquitination of a component of SC35 speckles GeneRIF 6427

The SR protein SC35 is responsible for aberrant splicing of the E1alpha pyruvate dehydrogenase mRNA in a case of mental retardation with lactic acidosis.

Gabut M., Mine M., Marsac C., Brivet M., Tazi J., Soret J.

Mol. Cell. Biol. 25:3286-3294(2005) GeneRIF 6427 · Mapped (10)
The mutation responsible for aberrant splicing of the E1alpha PDH mRNA increases binding of the SC35 protein in patients with Leigh disease. GeneRIF 6427

Dual effect of the SR proteins ASF/SF2, SC35 and 9G8 on HIV-1 RNA splicing and virion production.

Jacquenet S., Decimo D., Muriaux D., Darlix J.L.

Retrovirology 2:33-33(2005) GeneRIF 6427 · Mapped (16)
SR proteins ASF/SF2 SC35 and 9G8 can down-regulate the late steps of HIV-1 replication via negative impact on RNA splicing and virion production. GeneRIF 6427

Molecular anatomy of a speckle.

Hall L.L., Smith K.P., Byron M., Lawrence J.B.

Anat Rec A Discov Mol Cell Evol Biol 288:664-675(2006) GeneRIF 6427 · Mapped (10)
SC35 domains are hubs that spatially link expression of specific pre-mRNAs to rapid recycling of copious RNA metabolic complexes thereby facilitating expression of many highly active genes. GeneRIF 6427

Biochemical and NMR study on the competition between proteins SC35, SRp40, and heterogeneous nuclear ribonucleoprotein A1 at the HIV-1 Tat exon 2 splicing site.

Hallay H., Locker N., Ayadi L., Ropers D., Guittet E., Branlant C.

J. Biol. Chem. 281:37159-37174(2006) GeneRIF 6427 · Mapped (24)
SC35 SRp40 and heterogeneous nuclear ribonucleoprotein A1 interact competitively at the HIV-1 Tat exon 2 splicing site GeneRIF 6427

A role for SC35 and hnRNPA1 in the determination of amyloid precursor protein isoforms.

Donev R., Newall A., Thome J., Sheer D.

Mol. Psychiatry 12:681-690(2007) GeneRIF 6427 · Mapped (17)
This study demonstrates that binding of SC35 to Alu elements on either side of exon 7 in the transcribed pre-mRNA is involved in alternative splicing of amyloid precursor protein exons 7 and 8. GeneRIF 6427

Caffeine regulates alternative splicing in a subset of cancer-associated genes: a role for SC35.

Shi J., Hu Z., Pabon K., Scotto K.W.

Mol. Cell. Biol. 28:883-895(2008) GeneRIF 6427 · Mapped (10)
implicate SC35 as a key player in caffeine-mediated splicing regulation GeneRIF 6427

Growth hormone deficiency and splicing fidelity: two serine/arginine-rich proteins, ASF/SF2 and SC35, act antagonistically.

Solis A.S., Peng R., Crawford J.B., Phillips J.A., Patton J.G.

J. Biol. Chem. 283:23619-23626(2008) GeneRIF 6427 · Mapped (16)
Growth hormone deficiency and splicing fidelity: two serine/arginine-rich proteins ASF/SF2 and SC35 act antagonistically GeneRIF 6427

E2F1 controls alternative splicing pattern of genes involved in apoptosis through upregulation of the splicing factor SC35.

Merdzhanova G., Edmond V., De Seranno S., Van den Broeck A., Corcos L., Brambilla C., Brambilla E., Gazzeri S., Eymin B.

Cell Death Differ. 15:1815-1823(2008) GeneRIF 6427 · Mapped (12)
E2F1 controls pre-mRNA processing events to induce apoptosis and identify the SC35 Ser-Rich Arg protein as a key direct E2F1-target in this setting. GeneRIF 6427

Differential dynamics of splicing factor SC35 during the cell cycle.

Tripathi K., Parnaik V.K.

J. Biosci. 33:345-354(2008) GeneRIF 6427 · Mapped (10)
Dynamics of SC35 are significantly influenced by the organization of the compartment in which it is localized during the cell cycle. GeneRIF 6427

Subnuclear compartmentalization of transiently expressed polyadenylated pri-microRNAs: processing at transcription sites or accumulation in SC35 foci.

Pawlicki J.M., Steitz J.A.

Cell Cycle 8:345-356(2009) GeneRIF 6427 · Mapped (10)
Results suggest that pri-miRNA/SC35-containing foci are not major sites of pri-miRNA processing and that pri-miRNA processing is coupled to transcription. GeneRIF 6427

Functional role of transcriptional factor TBX5 in pre-mRNA splicing and Holt-Oram syndrome via association with SC35.

Fan C., Chen Q., Wang Q.K.

J. Biol. Chem. 284:25653-25663(2009) GeneRIF 6427 · Mapped (10)
complex formation between TBX5 and SC35 GeneRIF 6427

Antagonistic roles of four SR proteins in the biosynthesis of alternatively spliced tissue factor transcripts in monocytic cells.

Chandradas S., Deikus G., Tardos J.G., Bogdanov V.Y.

J. Leukoc. Biol. 87:147-152(2010) GeneRIF 6427 · Mapped (21)
SC35 antagonizes ASF/SF2 and SRp55 by competing for binding to certain sites in exon 5 thereby promoting TF exon 5 exclusion an event unique to asTF biosynthesis. GeneRIF 6427

Vitamin A metabolite, all-trans-retinoic acid, mediates alternative splicing of protein kinase C deltaVIII (PKCdeltaVIII) isoform via splicing factor SC35.

Apostolatos H., Apostolatos A., Vickers T., Watson J.E., Song S., Vale F., Cooper D.R., Sanchez-Ramos J., Patel N.A.

J. Biol. Chem. 285:25987-25995(2010) GeneRIF 6427 · Mapped (12)
SC35 is pivotal in RA-mediated PKCdelta pre-mRNA alternative splicing GeneRIF 6427

Expression of spliceosome assembly factor SC-35 in TUNEL-positive atrial cardiomyocytes in mitral and tricuspid regurgitation: viability of atrial cardiomyocytes.

Chen M.C., Chang J.P., Ho W.C., Liu W.H., Chen C.J., Yang C.H., Chen Y.L., Tsai T.H.

Int. J. Cardiol. 151:323-327(2011) GeneRIF 6427 · Mapped (18)
Most nuclei of TUNEL-positive myocytes in the fibrillating right atria express proliferating cell nuclear antigen and most nuclei of TUNEL-positive myocytes also express SC-35; none express Ki-67. GeneRIF 6427

Amyloid-beta peptide alteration of tau exon-10 splicing via the GSK3beta-SC35 pathway.

Chen K.L., Yuan R.Y., Hu C.J., Hsu C.Y.

Neurobiol. Dis. 40:378-385(2010) GeneRIF 6427 · Mapped (30)
Amyloid-beta peptide alteration of tau exon-10 splicing is causally related to its activation of GSK-3beta which in turn phosphorylates SC35. GeneRIF 6427

Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatin.

Edmond V., Moysan E., Khochbin S., Matthias P., Brambilla C., Brambilla E., Gazzeri S., Eymin B.

EMBO J. 30:510-523(2011) GeneRIF 6427 · UniProtKB (3) · Mapped (12)
Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatin. GeneRIF 6427

Splicing factor SC35 promotes tau expression through stabilization of its mRNA.

Qian W., Iqbal K., Grundke-Iqbal I., Gong C.X., Liu F.

FEBS Lett. 585:875-880(2011) GeneRIF 6427 · Mapped (16)
Data show that SC35 stabilized tau mRNA by binding to the SC35-like element of exon 10. GeneRIF 6427

The structure and selectivity of the SR protein SRSF2 RRM domain with RNA.

Phelan M.M., Goult B.T., Clayton J.C., Hautbergue G.M., Wilson S.A., Lian L.Y.

Nucleic Acids Res. 40:3232-3244(2012) GeneRIF 6427 · Mapped (11)
The interactions involving the L3 loop N- and C-termini of the RNA recognition motifs domain of SRSF2 are collectively important for determining selectivity between SRSF2 and RNA. GeneRIF 6427

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