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10 results for uniprot:Q15819 in Computationally mapped citations

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UBE2V2 (MMS2) is not required for effective immunoglobulin gene conversion or DNA damage tolerance in DT40.

Simpson L.J., Sale J.E.

DNA Repair (Amst.) 4:503-510(2005) GeneRIF 7336 · Mapped (4)
UBE2v2 signalling through PCNA ubiquitination is not required for immunoglobulin diversification in DT40 cells. GeneRIF 7336

A single Mms2 "key" residue insertion into a Ubc13 pocket determines the interface specificity of a human Lys63 ubiquitin conjugation complex.

Pastushok L., Moraes T.F., Ellison M.J., Xiao W.

J. Biol. Chem. 280:17891-17900(2005) GeneRIF 7336 · Mapped (4)
The results in this study allowed identification of important residues of the Ubc13-Mms2 interface determine a correlation between heterodimer formation and function and conclude why Mms2 forms a specific complex with Ubc13 but not other Ubc proteins. GeneRIF 7336

Main chain and side chain dynamics of the ubiquitin conjugating enzyme variant human Mms2 in the free and ubiquitin-bound States.

Spyracopoulos L., Lewis M.J., Saltibus L.F.

Biochemistry 44:8770-8781(2005) GeneRIF 7336 · Mapped (3)
Insight into the influence of protein dynamics on the affinity of ubiquitin for Mms2. GeneRIF 7336

Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A.

Andersen P.L., Zhou H., Pastushok L., Moraes T., McKenna S., Ziola B., Ellison M.J., Dixit V.M., Xiao W.

J. Cell Biol. 170:745-755(2005) GeneRIF 7336 · Mapped (7)
Data demonstrate that divergent activities of Ubc13 rely on its pairing with either of two Uevs Uev1A or Mms2. GeneRIF 7336

Two Mms2 residues cooperatively interact with ubiquitin and are critical for Lys63 polyubiquitination in vitro and in vivo.

Pastushok L., Spyracopoulos L., Xiao W.

FEBS Lett. 581:5343-5348(2007) GeneRIF 7336 · Mapped (5)
Mms2 physical association with ubiquitin is correlated with its ability to promote Lys63-linked ubiquitin chain assembly GeneRIF 7336

hMMS2 serves a redundant role in human PCNA polyubiquitination.

Brun J., Chiu R., Lockhart K., Xiao W., Wouters B.G., Gray D.A.

BMC Mol. Biol. 9:24-24(2008) GeneRIF 7336 · Mapped (11)
These results point to a high level of redundancy in the DNA damage tolerance pathway and suggest the existence of another hMMS2 variant (hMMSv) or complex that can compensate for its loss. GeneRIF 7336

Mutation screening of the RNF8, UBC13 and MMS2 genes in Northern Finnish breast cancer families.

Vuorela M., Pylkas K., Winqvist R.

BMC Med. Genet. 12:98-98(2011) GeneRIF 7336 · Mapped (5)
entire coding region and splice junctions of RNF8 UBC13 and MMS2 genes were screened for mutations in affected index cases from 123 Northern Finnish breast cancer families GeneRIF 7336

Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13.

Sato Y., Yamagata A., Goto-Ito S., Kubota K., Miyamoto R., Nakada S., Fukai S.

J. Biol. Chem. 287:25860-25868(2012) GeneRIF 7336 · Mapped (9)
the crystal structure of human OTUB1 in complex with human UBC13 and MMS2 GeneRIF 7336

Structural basis for non-covalent interaction between ubiquitin and the ubiquitin conjugating enzyme variant human MMS2.

Lewis M.J., Saltibus L.F., Hau D.D., Xiao W., Spyracopoulos L.

J. Biomol. NMR 34:89-100(2006) PDB 1ZGU · Mapped (2)

A human protein-protein interaction network: a resource for annotating the proteome.

Stelzl U., Worm U., Lalowski M., Haenig C., Brembeck F.H., Goehler H., Stroedicke M., Zenkner M., Schoenherr A., Koeppen S. et al.

Cell 122:957-968(2005) MINT MINT-1368221 MINT MINT-1368221 MINT MINT-1368221 MINT MINT-1368221 · UniProtKB (1) · Mapped (1,466)
MINT-64269. UBE2V2 (uniprotkb:Q15819) physically interacts (MI:0915) with IGSF21 (uniprotkb:Q96ID5) by two hybrid (MI:0018). From mint MINT MINT-1368221 MINT-64270. UBE2V2 (uniprotkb:Q15819) physically interacts (MI:0915) with C1orf103 (uniprotkb:Q5T3J3) by two hybrid (MI:0018). From mint MINT MINT-1368221 MINT-64397. SUV39H2 (uniprotkb:Q5JSS2) physically interacts (MI:0915) with UBE2V2 (uniprotkb:Q15819) by two hybrid (MI:0018). From mint MINT MINT-1368221 MINT-65831. MOBKL3 (uniprotkb:Q9Y3A3) physically interacts (MI:0915) with UBE2V2 (uniprotkb:Q15819) by two hybrid (MI:0018). From mint MINT MINT-1368221

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