Kentsis A., Gordon R.E., Borden K.L.

Proc. Natl. Acad. Sci. U.S.A. 99:15404-15409(2002) GeneRIF 10155 · Mapped (25)
Purified RINGs including KAP-1 self-assemble into supramolecular structures in vitro that resemble those they form in cells. GeneRIF 10155

Liao G., Huang J., Fixman E.D., Hayward S.D.

J. Virol. 79:245-256(2005) GeneRIF 10155 · Mapped (3)
interacts with BBLF2/3 to provide an origin-tethering function for the EBV replication complex GeneRIF 10155

Sripathy S.P., Stevens J., Schultz D.C.

Mol. Cell. Biol. 26:8623-8638(2006) GeneRIF 10155 · Mapped (9)
KAP1 functions to coordinate activities that dynamically regulate changes in histone modifications and deposition of HP1 to establish a de novo microenvironment of heterochromatin which is required for repression of gene transcription by KRAB-zfps. GeneRIF 10155

O'Geen H., Squazzo S.L., Iyengar S., Blahnik K., Rinn J.L., Chang H.Y., Green R., Farnham P.J.

PLoS Genet. 3:e89-e89(2007) GeneRIF 10155 · Mapped (2)
Expression of KRAB-box zinc finger genes may be controlled via an auto-regulatory mechanism involving KAP1. GeneRIF 10155

Kamitani S., Ohbayashi N., Ikeda O., Togi S., Muromoto R., Sekine Y., Ohta K., Ishiyama H., Matsuda T.

Biochem. Biophys. Res. Commun. 370:366-370(2008) GeneRIF 10155 · Mapped (12)
KAP1 interacts with STAT1 and regulates IFN/STAT1-mediated IRF-1 gene expression in collaboration with HDACs. GeneRIF 10155

Chang C.W., Chou H.Y., Lin Y.S., Huang K.H., Chang C.J., Hsu T.C., Lee S.C.

BMC Mol. Biol. 9:61-61(2008) GeneRIF 10155 · Mapped (5)
modulation of HP1beta-TIF1beta interaction through the phosphorylation/de-phosphorylation of TIF1beta/Ser473 may constitute a molecular switch that regulates the expression of particular genes GeneRIF 10155

Quenet D., Gasser V., Fouillen L., Cammas F., Sanglier-Cianferani S., Losson R., Dantzer F.

FASEB J. 22:3853-3865(2008) GeneRIF 10155 · Mapped (17)
The histone subcode: poly(ADP-ribose) polymerase-1 (Parp-1) and Parp-2 control cell differentiation by regulating the transcriptional intermediary factor TIF1beta and the heterochromatin protein HP1alpha GeneRIF 10155

Barde I., Laurenti E., Verp S., Groner A.C., Towne C., Padrun V., Aebischer P., Trumpp A., Trono D.

J. Virol. 83:5574-5580(2009) GeneRIF 10155 · Mapped (3)
KRAB/KAP1 regulation is fully functional within the context of episomal DNA GeneRIF 10155

Rambaud J., Desroches J., Balsalobre A., Drouin J.

J. Biol. Chem. 284:14147-14156(2009) GeneRIF 10155 · Mapped (2)
TIF1beta is an important coactivator of NGFI-B-dependent transcription. GeneRIF 10155

Chang P.C., Fitzgerald L.D., Van Geelen A., Izumiya Y., Ellison T.J., Wang D.H., Ann D.K., Luciw P.A., Kung H.J.

Cancer Res. 69:5681-5689(2009) GeneRIF 10155 · Mapped (2)
Data show that cellular transcriptional repressor KAP-1 plays a role in regulating KSHV latency and viral protein kinase modulates the chromatin remodeling function of this repressor. GeneRIF 10155

Cardinale S., Bergmann J.H., Kelly D., Nakano M., Valdivia M.M., Kimura H., Masumoto H., Larionov V., Earnshaw W.C.

Mol. Biol. Cell 20:4194-4204(2009) GeneRIF 10155 · Mapped (2)
Data show that the transcriptional corepressor KAP1 can inactivate the kinetochore. GeneRIF 10155

Peng H., Ivanov A.V., Oh H.J., Lau Y.F., Rauscher F.J.

J. Biol. Chem. 284:35670-35680(2009) GeneRIF 10155 · Mapped (32)
The KRAB-O protein can simultaneously bind KAP1 and SRY in a noncompetitive but also noncooperative manner. GeneRIF 10155

Yokoe T., Toiyama Y., Okugawa Y., Tanaka K., Ohi M., Inoue Y., Mohri Y., Miki C., Kusunoki M.

Ann. Surg. Oncol. 17:821-828(2010) GeneRIF 10155 · Mapped (2)
Overexpression of KAP1 is associated with peritoneal carcinomatosis in gastric cancer. GeneRIF 10155

Lai I.L., Lin T.P., Yao Y.L., Lin C.Y., Hsieh M.J., Yang W.M.

J. Biol. Chem. 285:7187-7196(2010) GeneRIF 10155 · Mapped (6)
Results not only show that HDAC10 regulates melanogenesis but also demonstrate that the transcriptional activities of Pax3 and KAP1 are intimately linked to their acetylation status. GeneRIF 10155

Noon A.T., Shibata A., Rief N., Lobrich M., Stewart G.S., Jeggo P.A., Goodarzi A.A.

Nat. Cell Biol. 12:177-184(2010) GeneRIF 10155 · Mapped (17)
53BP1 amplifies Mre11-NBS1 accumulation at late-repairing DSBs concentrating active ATM and leading to robust localized pKAP-1. GeneRIF 10155

Groner A.C., Meylan S., Ciuffi A., Zangger N., Ambrosini G., Denervaud N., Bucher P., Trono D.

PLoS Genet. 6:e1000869-e1000869(2010) GeneRIF 10155 · Mapped (3)
KRAB/KAP1 recruitment induces long-range repression through the spread of heterochromatin. GeneRIF 10155

Frietze S., O'Geen H., Blahnik K.R., Jin V.X., Farnham P.J.

PLoS ONE 5:E15082-E15082(2010) GeneRIF 10155 · UniProtKB (1) · Mapped (9)
analysis of a KRAB domain-containing ZNF (ZNF274) that is involved in recruitment of the KAP1 and SETDB1 to specific regions of the human genome GeneRIF 10155

Kepkay R., Attwood K.M., Ziv Y., Shiloh Y., Dellaire G.

Cell Cycle 10:308-322(2011) GeneRIF 10155 · Mapped (2)
The phosphorylation of KAP1 at S284 by ATM regulated the initial increase in PML NB number following the induction of DNA double breaks by etotoside. GeneRIF 10155

Narayan V., Halada P., Hernychova L., Chong Y.P., Zakova J., Hupp T.R., Vojtesek B., Ball K.L.

J. Biol. Chem. 286:14291-14303(2011) GeneRIF 10155 · Mapped (18)
analysis of binding of NPM1 TRIM28 and YB-1 to the Mf2 domain of IRF-1 GeneRIF 10155

Iyengar S., Ivanov A.V., Jin V.X., Rauscher F.J., Farnham P.J.

Mol. Cell. Biol. 31:1833-1847(2011) GeneRIF 10155 · Mapped (2)
Deletion of the RBCC domain abolished KAP1 binding to the 3' exons of zinc finger genes but KAP1 binding to promoter regions was unaffected. GeneRIF 10155

Maruyama A., Nishikawa K., Kawatani Y., Mimura J., Hosoya T., Harada N., Yamamato M., Itoh K.

Biochem. J. 436:387-397(2011) GeneRIF 10155 · Mapped (12)
KAP1 [KRAB (Kruppel-associated box)-associated protein 1)] GeneRIF 10155

Iyengar S., Farnham P.J.

J. Biol. Chem. 286:26267-26276(2011) GeneRIF 10155 · Mapped (2)
KAP1 protein: an enigmatic master regulator of the genome. GeneRIF 10155

Allouch A., Di Primio C., Alpi E., Lusic M., Arosio D., Giacca M., Cereseto A.

Cell Host Microbe 9:484-495(2011) GeneRIF 10155 · Mapped (2)
KAP1 inhibits HIV-1 integration via binding to acetylated HIV-1 integrase. GeneRIF 10155

Meylan S., Groner A.C., Ambrosini G., Malani N., Quenneville S., Zangger N., Kapopoulou A., Kauzlaric A., Rougemont J., Ciuffi A. et al.

BMC Genomics 12:378-378(2011) GeneRIF 10155 · Mapped (3)
high levels of gene activity in the genomic environment and the pre-deposition of repressive histone marks within a gene increase its susceptibility to KRAB/KAP1-mediated repression GeneRIF 10155

Xiao T.Z., Bhatia N., Urrutia R., Lomberk G.A., Simpson A., Longley B.J.

PLoS ONE 6:e23747-e23747(2011) GeneRIF 10155 · Mapped (10)
Expression of MAGE I proteins MAGE-A3 or MAGE-C2 relieved repression of a reporter gene by ZNF382 and MAGE I expression relieved KAP1 mediated ID1 repression. GeneRIF 10155