Strobeck M.W., Reisman D.N., Gunawardena R.W., Betz B.L., Angus S.P., Knudsen K.E., Kowalik T.F., Weissman B.E., Knudsen E.S.

J. Biol. Chem. 277:4782-4789(2002) GeneRIF 6597 · Mapped (17)
majority of tumor lines with germ line defects in BRG-1 were sensitive to RB-mediated cell cycle arrest GeneRIF 6597

Narlikar G.J., Phelan M.L., Kingston R.E.

Mol. Cell 8:1219-1230(2001) GeneRIF 6597 · Mapped (9)
generation and interconversion of multiple distinct nucleosomal states as a mechanism for catalyzing chromatin fluidity GeneRIF 6597

Wang S., Hankinson O.

J. Biol. Chem. 277:11821-11827(2002) GeneRIF 6597 · Mapped (21)
Functional involvement of the Brahma/SWI2-related gene 1 protein in cytochrome P4501A1 transcription mediated by the aryl hydrocarbon receptor complex GeneRIF 6597

Peterson C.L.

Curr. Biol. 12:R245-7(2002) GeneRIF 6597 · Mapped (9)
BRG1 enzymes generate localized changes in DNA topology that drive formation of multiple remodeled nucleosomal states. GeneRIF 6597

Lee D., Kim J.W., Seo T., Hwang S.G., Choi E.J., Choe J.

J. Biol. Chem. 277:22330-22337(2002) GeneRIF 6597 · Mapped (17)
SWI/SNF complex interacts with tumor suppressor p53 and is necessary for the activation of p53-mediated transcription GeneRIF 6597

Pattenden S.G., Klose R., Karaskov E., Bremner R.

EMBO J. 21:1978-1986(2002) GeneRIF 6597 · Mapped (30)
Interferon-gamma-induced chromatin remodeling at the CIITA locus is BRG1 dependent GeneRIF 6597

Wang S., Zhang B., Faller D.V.

EMBO J. 21:3019-3028(2002) GeneRIF 6597 · Mapped (16)
Data show that prohibitin recruits Brg-1/Brm to E2F-responsive promoters and that this recruitment is required for the repression of E2F-mediated transcription by prohibitin. GeneRIF 6597

Mudhasani R., Fontes J.D.

Mol. Cell. Biol. 22:5019-5026(2002) GeneRIF 6597 · Mapped (18)
CIITA requires the ATPase subunit of an hSWI/SNF complex brahma-related gene 1 (BRG-1) to activate transcription. GeneRIF 6597

Battaglioli E., Andres M.E., Rose D.W., Chenoweth J.G., Rosenfeld M.G., Anderson M.E., Mandel G.

J. Biol. Chem. 277:41038-41045(2002) GeneRIF 6597 · UniProtKB (3) · Mapped (11)
REST repression of neuronal genes requires components of the hSWI.SNF complex GeneRIF 6597

Huang M., Qian F., Hu Y., Ang C., Li Z., Wen Z.

Nat. Cell Biol. 4:774-781(2002) GeneRIF 6597 · Mapped (9)
BRG1 interacts with signal transducer and activator of transcription 2 (STAT2) - a transcription factor that regulates gene expression mediated by interferon-alpha. GeneRIF 6597

Nielsen A.L., Sanchez C., Ichinose H., Cervino M., Lerouge T., Chambon P., Losson R.

EMBO J. 21:5797-5806(2002) GeneRIF 6597 · Mapped (12)
suggestion of an entirely novel function for BRG1 in modulating HP1alpha-containing heterochromatic structures GeneRIF 6597

Yamamichi-Nishina M., Ito T., Mizutani T., Yamamichi N., Watanabe H., Iba H.

J. Biol. Chem. 278:7422-7430(2003) GeneRIF 6597 · Mapped (17)
human adrenal carcinoma cells can spontaneously transition between two subtypes by switching expression of BRG1 and Brm at the post-transcriptional level GeneRIF 6597

Reisman D.N., Sciarrotta J., Wang W., Funkhouser W.K., Weissman B.E.

Cancer Res. 63:560-566(2003) GeneRIF 6597 · Mapped (17)
This report provides supportive evidence that BRG1 and BRM act as tumor suppressor proteins and implicates a role for their loss in the development of non-small cell lung cancers. GeneRIF 6597

Gwack Y., Baek H.J., Nakamura H., Lee S.H., Meisterernst M., Roeder R.G., Jung J.U.

Mol. Cell. Biol. 23:2055-2067(2003) GeneRIF 6597 · Mapped (18)
The Brg1 subunit of SWI/SNF was shown to interact directly with RTA. GeneRIF 6597

Kadam S., Emerson B.M.

Mol. Cell 11:377-389(2003) GeneRIF 6597 · Mapped (17)
BRG1 and BRM complexes may direct distinct cellular processes by recruitment to specific promoters through protein-protein interactions that are unique to each ATPase. GeneRIF 6597

Valdman A., Nordenskjold A., Fang X., Naito A., Al-Shukri S., Larsson C., Ekman P., Li C.

Int. J. Oncol. 22:1003-1007(2003) GeneRIF 6597 · Mapped (14)
Some mutations are found in prostate cancer such as germline mutation SNPs but common mutations are excluded. GeneRIF 6597

Shimono Y., Murakami H., Kawai K., Wade P.A., Shimokata K., Takahashi M.

J. Biol. Chem. 278:51638-51645(2003) GeneRIF 6597 · UniProtKB (2) · Mapped (11)
the amino-terminal and carboxyl-terminal regions of Mi-2 beta have distinct transcriptional activities and bind to BRG1 and the RET finger protein forming a multiprotein supercomplex involved in transcriptional regulation. GeneRIF 6597

Chi Y., Senyuk V., Chakraborty S., Nucifora G.

J. Biol. Chem. 278:49806-49811(2003) GeneRIF 6597 · Mapped (38)
BRG1 has a role in promoting cell proliferation by interacting with EVI1 which blocks its repression on E2F1 activity GeneRIF 6597

Doan D.N., Veal T.M., Yan Z., Wang W., Jones S.N., Imbalzano A.N.

Oncogene 23:3462-3473(2004) GeneRIF 6597 · Mapped (17)
in human cells SWI/SNF enzyme complex formation and the expression of many BRG1-dependent genes are independent of INI1. GeneRIF 6597

Wang S., Zhang B., Faller D.V.

EMBO J. 23:2293-2303(2004) GeneRIF 6597 · Mapped (16)
BRG1 is required for growth suppression by estrogen antagonists. GeneRIF 6597

Fukuoka J., Fujii T., Shih J.H., Dracheva T., Meerzaman D., Player A., Hong K., Settnek S., Gupta A., Buetow K. et al.

Clin. Cancer Res. 10:4314-4324(2004) GeneRIF 6597 · Mapped (17)
BRM and BRG1 participate in two distinct chromosome remodeling complexes that are functionally complementary in non-small cell lung cancer GeneRIF 6597

Giraud S., Hurlstone A., Avril S., Coqueret O.

Oncogene 23:7391-7398(2004) GeneRIF 6597 · Mapped (19)
Sta3 regulates chromatin remodeling and transcription elongation through its interaction with BRG1 and cdk9 GeneRIF 6597

Medina P.P., Carretero J., Fraga M.F., Esteller M., Sidransky D., Sanchez-Cespedes M.

Genes Chromosomes Cancer 41:170-177(2004) GeneRIF 6597 · Mapped (14)
Somatic point mutations of the BRG1 gene are present in a small subset of lung tumors; Somatic point mutations of the SMARCA4 gene are present in a small subset of lung tumors. GeneRIF 6597

Ma Z., Chang M.J., Shah R., Adamski J., Zhao X., Benveniste E.N.

J. Biol. Chem. 279:46326-46334(2004) GeneRIF 6597 · Mapped (11)
Brg-1 plays a role in regulating the recruitment of Sp1 Sp3 AP-2 and polymerase II to the MMP-2 promoter. GeneRIF 6597

Wang F., Zhang R., Beischlag T.V., Muchardt C., Yaniv M., Hankinson O.

J. Biol. Chem. 279:46733-46741(2004) GeneRIF 6597 · Mapped (18)
Brahma and Brahma/SWI2-related gene 1 have roles in hypoxic induction of the erythropoietin gene GeneRIF 6597