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The Drosophila gene 2A5 complements the defect in mitochondrial F1-ATPase assembly in yeast lacking the molecular chaperone Atp11p.

Wang Z.G., Schmid K.J., Ackerman S.H.

FEBS Lett. 452:305-308(1999) SGD S000005259 · Mapped (5)
Fungal Related Genes/Proteins|Non-Fungal Related Genes/Proteins SGD S000005259

The assembly factor Atp11p binds to the beta-subunit of the mitochondrial F(1)-ATPase.

Wang Z.G., Ackerman S.H.

J. Biol. Chem. 275:5767-5772(2000) SGD S000005259 · Mapped (4)
Function/Process|Protein-protein Interactions SGD S000005259

The alpha-subunit of the mitochondrial F(1) ATPase interacts directly with the assembly factor Atp12p.

Wang Z.G., Sheluho D., Gatti D.L., Ackerman S.H.

EMBO J. 19:1486-1493(2000) SGD S000005259 · Mapped (4)
Function/Process|Fungal Related Genes/Proteins|Mutants/Phenotypes|Protein Physical Properties|Protein Sequence Features|Protein-protein Interactions|Protein/Nucleic Acid Structure|Strains/Constructs SGD S000005259

Identification of a nuclear gene (FMC1) required for the assembly/stability of yeast mitochondrial F(1)-ATPase in heat stress conditions.

Lefebvre-Legendre L., Vaillier J., Benabdelhak H., Velours J., Slonimski P.P., di Rago J.-P.

J. Biol. Chem. 276:6789-6796(2001) SGD S000005259 · UniProtKB (1) · Mapped (16)
Function/Process|Fungal Related Genes/Proteins SGD S000005259

Atp11p and Atp12p are assembly factors for the F(1)-ATPase in human mitochondria.

Wang Z.-G., White P.S., Ackerman S.H.

J. Biol. Chem. 276:30773-30778(2001) SGD S000005259 · UniProtKB (3) · Mapped (2)
Non-Fungal Related Genes/Proteins SGD S000005259

An accessible hydrophobic surface is a key element of the molecular chaperone action of Atp11p.

Sheluho D., Ackerman S.H.

J. Biol. Chem. 276:39945-39949(2001) SGD S000005259 · Mapped (1)
Cellular Location|Function/Process|Protein Sequence Features|Protein-protein Interactions|Protein/Nucleic Acid Structure|Substrates/Ligands/Cofactors SGD S000005259

Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae.

Dimmer K.S., Fritz S., Fuchs F., Messerschmitt M., Weinbach N., Neupert W., Westermann B.

Mol. Biol. Cell 13:847-853(2002) SGD S000005259 · UniProtKB (11) · Mapped (432)
Function/Process|Mutants/Phenotypes SGD S000005259

Atp11p and Atp12p are chaperones for F(1)-ATPase biogenesis in mitochondria.

Ackerman S.H.

Biochim. Biophys. Acta 1555:101-105(2002) SGD S000005259 · Mapped (2)
Disease Gene Related|Function/Process|Fungal Related Genes/Proteins|Protein Sequence Features|Protein-protein Interactions SGD S000005259

F1-catalysed ATP hydrolysis is required for mitochondrial biogenesis in Saccharomyces cerevisiae growing under conditions where it cannot respire.

Lefebvre-Legendre L., Balguerie A., Duvezin-Caubet S., Giraud M.F., Slonimski P.P., Di Rago J.P.

Mol. Microbiol. 47:1329-1339(2003) SGD S000005259 · Mapped (7)
Function/Process|Mutants/Phenotypes|Strains/Constructs SGD S000005259

A purified subfragment of yeast Atp11p retains full molecular chaperone activity.

Hinton A., Zuiderweg E.R., Ackerman S.H.

J. Biol. Chem. 278:34110-34113(2003) SGD S000005259 · Mapped (1)
Function/Process|Mutants/Phenotypes|Protein Physical Properties|Protein Sequence Features|Strains/Constructs SGD S000005259

The proteome of Saccharomyces cerevisiae mitochondria.

Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E., Schoenfisch B., Perschil I., Chacinska A., Guiard B. et al.

Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003) SGD S000005259 · UniProtKB (221) · Mapped (571)
Cellular Location SGD S000005259

Cardiolipin biosynthesis and mitochondrial respiratory chain function are interdependent.

Gohil V.M., Hayes P., Matsuyama S., Schagger H., Schlame M., Greenberg M.L.

J. Biol. Chem. 279:42612-42618(2004) SGD S000005259 · Mapped (7)
Mutants/Phenotypes|Strains/Constructs SGD S000005259

Failure to assemble the alpha 3 beta 3 subcomplex of the ATP synthase leads to accumulation of the alpha and beta subunits within inclusion bodies and the loss of mitochondrial cristae in Saccharomyces cerevisiae.

Lefebvre-Legendre L., Salin B., Schaeffer J., Brethes D., Dautant A., Ackerman S.H., di Rago J.P.

J. Biol. Chem. 280:18386-18392(2005) SGD S000005259 · Mapped (6)
Function/Process|Mutants/Phenotypes|Strains/Constructs SGD S000005259

Assembly factors of F1FO-ATP synthase across genomes.

Pickova A., Potocky M., Houstek J.

Proteins 59:393-402(2005) SGD S000005259 · Mapped (5)
Function/Process|Non-Fungal Related Genes/Proteins|Protein Sequence Features SGD S000005259

A genomewide screen reveals a role of mitochondria in anaerobic uptake of sterols in yeast.

Reiner S., Micolod D., Zellnig G., Schneiter R.

Mol. Biol. Cell 17:90-103(2006) SGD S000005259 · Mapped (43)
Function/Process|Genetic Interactions|Mutants/Phenotypes|Strains/Constructs SGD S000005259

Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.

J. Proteome Res. 5:1543-1554(2006) SGD S000005259 · UniProtKB (44) · Mapped (852)
Cellular Location SGD S000005259

Intracellular sterol transport in eukaryotes, a connection to mitochondrial function?

Schneiter R.

Biochimie 89:255-259(2007) SGD S000005259 · Mapped (18)
Reviews SGD S000005259

Structural organization of mitochondrial ATP synthase.

Wittig I., Schagger H.

Biochim. Biophys. Acta 1777:592-598(2008) SGD S000005259 · Mapped (35)
Non-Fungal Related Genes/Proteins|Protein Physical Properties|Protein Sequence Features|Protein/Nucleic Acid Structure SGD S000005259

Assembly of F0 in Saccharomyces cerevisiae.

Rak M., Zeng X., Briere J.J., Tzagoloff A.

Biochim. Biophys. Acta 1793:108-116(2009) SGD S000005259 · Mapped (39)
Reviews SGD S000005259

Rsf1p is required for an efficient metabolic shift from fermentative to glycerol-based respiratory growth in S. cerevisiae.

Roberts G.G. III, Hudson A.P.

Yeast 26:95-110(2009) SGD S000005259 · UniProtKB (1) · Mapped (218)
RNA Levels and Processing|Regulation of SGD S000005259

Multiple defects in the respiratory chain lead to the repression of genes encoding components of the respiratory chain and TCA cycle enzymes.

Bourges I., Mucchielli M.H., Herbert C.J., Guiard B., Dujardin G., Meunier B.

J. Mol. Biol. 387:1081-1091(2009) SGD S000005259 · Mapped (48)
RNA Levels and Processing|Regulation of SGD S000005259

Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability.

Vogtle F.N., Wortelkamp S., Zahedi R.P., Becker D., Leidhold C., Gevaert K., Kellermann J., Voos W., Sickmann A., Pfanner N. et al.

Cell 139:428-439(2009) SGD S000005259 · Mapped (42)
Protein Processing/Modification/Regulation|Protein Sequence Features|Regulation of SGD S000005259

F1-dependent translation of mitochondrially encoded Atp6p and Atp8p subunits of yeast ATP synthase.

Rak M., Tzagoloff A.

Proc. Natl. Acad. Sci. U.S.A. 106:18509-18514(2009) SGD S000005259 · Mapped (22)
S000005259 SGD S000005259

Identification of two nuclear genes (ATP11, ATP12) required for assembly of the yeast F1-ATPase.

Ackerman S.H., Tzagoloff A.

Proc. Natl. Acad. Sci. U.S.A. 87:4986-4990(1990) SGD S000005259 · Mapped (2)
Cellular Location|Function/Process|Mutants/Phenotypes|Protein Processing/Modification/Regulation SGD S000005259

Bacterial production and characterization of ATP11, a yeast protein required for mitochondrial F1-ATPase assembly.

White M., Ackerman S.H.

Arch. Biochem. Biophys. 319:299-304(1995) SGD S000005259 · Mapped (1)
Cellular Location|Function/Process|Mutants/Phenotypes|Protein Physical Properties|Protein Processing/Modification/Regulation|Protein Sequence Features|Strains/Constructs|Techniques and Reagents SGD S000005259

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