Smith I., Vedeler C., Halstensen A.

Epidemiol. Infect. 130:193-199(2003) GAD 139397 GeneRIF 2213 · Mapped (8)
Not Associated with INFECTION: meningococcal disease; GAD 139397 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) GeneRIF 2213

Yasuda K., Sugita N., Kobayashi T., Yamamoto K., Yoshie H.

Genes Immun. 4:541-546(2003) GAD 139394 GeneRIF 2213 · Mapped (6)
Associated with IMMUNE: periodontitis; GAD 139394 Observational study of gene-disease association. (HuGE Navigator) GeneRIF 2213

Chu Z.T., Tsuchiya N., Kyogoku C., Ohashi J., Qian Y.P., Xu S.B., Mao C.Z., Chu J.Y., Tokunaga K.

Tissue Antigens 63:21-27(2004) GAD 139399 GeneRIF 2213 · Mapped (15)
Associated with IMMUNE: lupus erythematosus; GAD 139399 FCGR2B is a common susceptibility factor to SLE in the Asians; Observational study and meta-analysis of gene-disease association. (HuGE Navigator) GeneRIF 2213

Magnusson V., Zunec R., Odeberg J., Sturfelt G., Truedsson L., Gunnarsson I., Alarcon-Riquelme M.E.

Arthritis Rheum. 50:1348-1350(2004) GAD 139388 GeneRIF 2213 GAD 139391 · Mapped (6)
Not Associated with IMMUNE: systemic lupus erythematosus; GAD 139388 GAD 139391 no association between fcgammar2b and systemic lupus erythematosus in Swedish population GeneRIF 2213

Pan F., Zhang K., Li X., Xu J., Hao J., Ye D.

J. Dermatol. Sci. 43:35-41(2006) GAD 147628 GeneRIF 2213 · Mapped (6)
Associated with IMMUNE: lupus erythematosus; GAD 147628 Observational study of gene-disease association. (HuGE Navigator); the FcgammaRIIB-50T-225C haplotype might be a susceptible factor of SLE in the Chinese population GeneRIF 2213

Radstake T.R., Franke B., Wenink M.H., Nabbe K.C., Coenen M.J., Welsing P., Bonvini E., Koenig S., van den Berg W.B., Barrera P. et al.

Arthritis Rheum. 54:3828-3837(2006) GAD 147630 GeneRIF 2213 · Mapped (6)
Associated with IMMUNE: rheumatoid arthritis; GAD 147630 Observational study of gene-disease association. (HuGE Navigator); FCGR2B 695T>C polymorphism is a critical determinant of severity in rheumatoid arthritis and is a potential therapeutic target. GeneRIF 2213

Zhou X.J., Lv J.C., Yu L., Cui Z., Zhao J., Yang R., Han J., Hou P., Zhao M.H., Zhang H.

Nephrol. Dial. Transplant. 25:97-101(2010) GAD 575913 GeneRIF 2213 · Mapped (18)
Associated with IMMUNE: anti-GBM disease; GAD 575913 Observational study of gene-disease association. (HuGE Navigator); FCGR2B gene polymorphism is associated with anti-glomerular basement membrane antibody disease in Chinese. GeneRIF 2213

Pricop L., Redecha P., Teillaud J.L., Frey J., Fridman W.H., Sautes-Fridman C., Salmon J.E.

J. Immunol. 166:531-537(2001) GeneRIF 2213 · Mapped (6)
The inhibitory receptor Fc gamma RIIb2 is expressed on circulating human monocytes. In human primary monocytes Fc gamma RIIb2 expression is increased by IL-4 a Th2 cytokine and decreased by IFN-gamma a Th1 cytokine. GeneRIF 2213

Jessup C.F., Ridings J., Ho A., Nobbs S., Roberton D.M., Macardle P., Zola H.

Hum. Immunol. 62:679-685(2001) GeneRIF 2213 · Mapped (6)
Although there is no phenotypic difference in Fc gamma RII expression (Fc gamma RIIb predominating on both adult and cord B cells) the inhibitory Fc gamma RIIb is expressed at lower levels on cord cells. GeneRIF 2213

Tridandapani S., Siefker K., Teillaud J.L., Carter J.E., Wewers M.D., Anderson C.L.

J. Biol. Chem. 277:5082-5089(2002) GeneRIF 2213 · Mapped (6)
Here we demonstrate for the first time FcgammaRIIb protein expression and function in human monocytes GeneRIF 2213

Cassard L., Cohen-Solal J.F., Galinha A., Sastre-Garau X., Mathiot C., Galon J., Dorval T., Bernheim A., Fridman W.H., Sautes-Fridman C.

J. Clin. Invest. 110:1549-1557(2002) GeneRIF 2213 · Mapped (6)
human malignant melanoma cells express the inhibitory low-affinity Fc(gamma) receptor Fc(gamma)RIIB1 in 40% of tested metastases GeneRIF 2213

Kyogoku C., Tsuchiya N., Matsuta K., Tokunaga K.

Genes Immun. 3:488-493(2002) GeneRIF 2213 GAD 139387 · Mapped (321)
Not Associated with IMMUNE: rheumatoid arthritis; GAD 139387 Observational study of gene-disease association. (HuGE Navigator) GeneRIF 2213

Macardle P.J., Mardell C., Bailey S., Wheatland L., Ho A., Jessup C., Roberton D.M., Zola H.

Eur. J. Immunol. 32:3736-3744(2002) GeneRIF 2213 · Mapped (6)
hypothesized that inhibitory signaling through FcgammaRIIb would be counter-productive in germinal center cells undergoing selection by affinity maturation GeneRIF 2213

Siriboonrit U., Tsuchiya N., Sirikong M., Kyogoku C., Bejrachandra S., Suthipinittharm P., Luangtrakool K., Srinak D., Thongpradit R., Fujiwara K. et al.

Tissue Antigens 61:374-383(2003) GeneRIF 2213 · Mapped (8)
Fcgamma receptor IIb polymorphisms are associated with susceptibility to systemic lupus erythematosus in Thais; Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) GeneRIF 2213

van der Pol W.L., Jansen M.D., Sluiter W.J., van de Sluis B., Leppers-van de Straat F.G., Kobayashi T., Westendorp R.G., Huizinga T.W., van de Winkel J.G.

Immunogenetics 55:240-246(2003) GeneRIF 2213 · Mapped (18)
Observational study of genotype prevalence. (HuGE Navigator) GeneRIF 2213

Tsuchiya N., Kobayashi S., Kawasaki A., Kyogoku C., Arimura Y., Yoshida M., Tokunaga K., Hashimoto H.

J. Rheumatol. 30:1534-1540(2003) GeneRIF 2213 · Mapped (340)
Observational study of gene-disease association. (HuGE Navigator) GeneRIF 2213

Li X., Wu J., Carter R.H., Edberg J.C., Su K., Cooper G.S., Kimberly R.P.

Arthritis Rheum. 48:3242-3252(2003) GeneRIF 2213 · Mapped (6)
The differential activity of FCGR2B alleles suggests a novel mechanism of FcgammaRIIb regulation that may influence the risk of autoimmune disease. GeneRIF 2213

Su K., Wu J., Edberg J.C., Li X., Ferguson P., Cooper G.S., Langefeld C.D., Kimberly R.P.

J. Immunol. 172:7186-7191(2004) GeneRIF 2213 GAD 139398 · Mapped (15)
Associated with IMMUNE: lupus erythematosus; GAD 139398 Observational study of gene-disease association. (HuGE Navigator) GeneRIF 2213

Hitomi Y., Tsuchiya N., Kawasaki A., Ohashi J., Suzuki T., Kyogoku C., Fukazawa T., Bejrachandra S., Siriboonrit U., Chandanayingyong D. et al.

Hum. Mol. Genet. 13:2907-2917(2004) GeneRIF 2213 GAD 139396 · UniProtKB (5) · Mapped (9)
Associated with IMMUNE: lupus erythematosus; GAD 139396 Observational study of gene-disease association. (HuGE Navigator); results indicated that the presence of CD72-*2 allele decreases risk for human systemic lupus erythematosus conferred by FCGR2B-232Thr possibly by increasing the AS isoform of CD72 GeneRIF 2213

Carter N.A., Harnett M.M.

Biochem. Soc. Trans. 32:973-975(2004) GeneRIF 2213 · Mapped (6)
Signals underlying FcgammaRIIB-driven apoptosis are dependent on disruption of mitochondrial potential. GeneRIF 2213

Bruin M., Bierings M., Uiterwaal C., Revesz T., Bode L., Wiesman M.E., Kuijpers T., Tamminga R., de Haas M.

Br. J. Haematol. 127:561-567(2004) GeneRIF 2213 · Mapped (6)
Observational study of gene-disease association. (HuGE Navigator) GeneRIF 2213

Riemann D., Tcherkes A., Hansen G.H., Wulfaenger J., Blosz T., Danielsen E.M.

Biochem. Biophys. Res. Commun. 331:1408-1412(2005) GeneRIF 2213 · Mapped (17)
results imply a novel functional role of CD13 and Fc gamma receptors (CD32 and CD64)as members of a multimeric receptor complex GeneRIF 2213

Torkildsen O., Utsi E., Mellgren S.I., Harbo H.F., Vedeler C.A., Myhr K.M.

Immunology 115:416-421(2005) GeneRIF 2213 · Mapped (15)
Observational study of genotype prevalence. (HuGE Navigator) GeneRIF 2213

Joshi T., Ganesan L.P., Cao X., Tridandapani S.

Mol. Immunol. 43:839-850(2006) GeneRIF 2213 · Mapped (6)
FcgammaRIIbl and b2 are both functional inhibitory receptors in the phagocytic process. GeneRIF 2213

Kono H., Kyogoku C., Suzuki T., Tsuchiya N., Honda H., Yamamoto K., Tokunaga K., Honda Z.

Hum. Mol. Genet. 14:2881-2892(2005) GeneRIF 2213 · Mapped (6)
Ile232Thr substitution affects the localization and function of FcgammaRIIB; this molecular mechanism may link the polymorphism and susceptibility to systemic lupus erythematosus. GeneRIF 2213