| Mammalian, yeast, bacterial, and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophy. Bao Y.P., Cook L.J., O'Donovan D., Uyama E., Rubinsztein D.C.
J. Biol. Chem. 277:12263-12269(2002) GeneRIF 3301 · Mapped (10)
Mammalian yeast bacterial and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophy GeneRIF 3301 |
| HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor. Hernandez M.P., Chadli A., Toft D.O.
J. Biol. Chem. 277:11873-11881(2002) GeneRIF 3301 · Mapped (16)
HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor GeneRIF 3301 |
| Characterization of two isoforms of a human DnaJ homologue, HSJ2. Hanai R., Mashima K.
Mol. Biol. Rep. 30:149-153(2003) GeneRIF 3301 · UniProtKB (1) · Mapped (5)
sequence analysis of two isoforms GeneRIF 3301 |
| Expression of a novel DnaJA1 alternative splicing in human testis and sperm. Hu Y., Zhou Z., Huang X., Xu M., Lu L., Xu Z., Li J., Sha J.
Int. J. Androl. 27:343-349(2004) GeneRIF 3301 · UniProtKB (1) · Mapped (4)
Multiple tissue polymerase chain reaction (PCR) results showed that nDnaJA1 expressed highly in testis and lung but low in thymus prostate colon and liver GeneRIF 3301 |
| Low resolution structural study of two human HSP40 chaperones in solution. DJA1 from subfamily A and DJB4 from subfamily B have different quaternary structures. Borges J.C., Fischer H., Craievich A.F., Ramos C.H.I.
J. Biol. Chem. 280:13671-13681(2005) GeneRIF 3301 · UniProtKB (1) · Mapped (8)
Results indicate that DjA1 and DjB4 of subfamilies A and B of human Hsp40 have different quaternary structures and chaperone functions. GeneRIF 3301 |
| Functional divergence between co-chaperones of Hsc70. Tzankov S., Wong M.J., Shi K., Nassif C., Young J.C.
J. Biol. Chem. 283:27100-27109(2008) GeneRIF 3301 · Mapped (19)
DJA1 was inhibitory of refolding with DJA2 and Hsc70. GeneRIF 3301 |
| Hsp40 chaperones promote degradation of the HERG potassium channel. Walker V.E., Wong M.J., Atanasiu R., Hantouche C., Young J.C., Shrier A.
J. Biol. Chem. 285:3319-3329(2010) GeneRIF 3301 · Mapped (20)
Hsp40 type 1 chaperones DJA1 (DNAJA1/Hdj2) and DJA2 (DNAJA2) as key modulators of hERG degradation GeneRIF 3301 |
| Multiple molecules of Hsc70 and a dimer of DjA1 independently bind to an unfolded protein. Terada K., Oike Y.
J. Biol. Chem. 285:16789-16797(2010) GeneRIF 3301 · Mapped (8)
Hsc70 and a dimer of DjA1 independently bind to an unfolded protein GeneRIF 3301 |
| Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study. Flachsbart F., Franke A., Kleindorp R., Caliebe A., Blanche H., Schreiber S., Nebel A.
Mutat. Res. 694:13-19(2010) GeneRIF 3301 · Mapped (1,167)
Observational study of gene-disease association. (HuGE Navigator) GeneRIF 3301 |
| DnaJ homolog Hdj2 facilitates Japanese encephalitis virus replication. Wang R.Y., Huang Y.R., Chong K.M., Hung C.Y., Ke Z.L., Chang R.Y.
Virol. J. 8:471-471(2011) GeneRIF 3301 · Mapped (5)
Hdj2 directly associates with Japanese encephalitis virus nonstructural protein NS5 and facilitates viral replication. GeneRIF 3301 |
| DnaJA1 antagonizes constitutive Hsp70-mediated stabilization of tau. Abisambra J.F., Jinwal U.K., Suntharalingam A., Arulselvam K., Brady S., Cockman M., Jin Y., Zhang B., Dickey C.A.
J. Mol. Biol. 421:653-661(2012) GeneRIF 3301 · Mapped (27)
Moreover the levels of DnaJA1 and Hsp70 seem to play against each other with regard to tau: as DnaJA1 levels increase tau levels are reduced but this can be prevented if Hsp70 levels are simultaneously induced. GeneRIF 3301 |
| Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. Lehner B., Semple J.I., Brown S.E., Counsell D., Campbell R.D., Sanderson C.M.
Genomics 83:153-167(2004) MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 · UniProtKB (3) · Mapped (86)
MINT-62596. LSM2 (uniprotkb:Q9Y333) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by two hybrid (MI:0018). From mint MINT MINT-5004184 MINT-62694. LSM2 (uniprotkb:Q9Y333) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by two hybrid (MI:0018). From mint MINT MINT-5004184 MINT-62770. LSM2 (uniprotkb:Q9Y333) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by two hybrid (MI:0018). From mint MINT MINT-5004184 |
| A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. Bouwmeester T., Bauch A., Ruffner H., Angrand P.-O., Bergamini G., Croughton K., Cruciat C., Eberhard D., Gagneur J., Ghidelli S. et al.
Nat. Cell Biol. 6:97-105(2004) MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 · UniProtKB (5) · Mapped (512)
MINT-48291. MAP3K1 (uniprotkb:Q13233) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-48406. MAP3K3 (uniprotkb:Q99759) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-48650. NFKB1 (uniprotkb:P19838) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-48711. NFKB2 (uniprotkb:Q00653) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-48805. MAP3K14 (uniprotkb:Q99558) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-48909. RELA (uniprotkb:Q04206-2) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-49044. RIPK1 (uniprotkb:Q13546) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-49096. RIPK3 (uniprotkb:Q9Y572) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-49166. MAP3K7IP1 (uniprotkb:Q15750) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-49190. MAP3K7IP2 (uniprotkb:Q9NYJ8) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-49223. MAP3K7 (uniprotkb:O43318-2) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-49310. TNFRSF1A (uniprotkb:P19438) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-49391. TNFRSF1B (uniprotkb:P20333) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-49471. TRADD (uniprotkb:Q15628) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-49507. TRAF1 (uniprotkb:Q13077) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-49539. TRAF2 (uniprotkb:Q12933) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 MINT-49575. TRAF6 (uniprotkb:Q9Y4K3) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by anti tag coimmunoprecipitation (MI:0007). From mint MINT MINT-5004184 |
| A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U., Worm U., Lalowski M., Haenig C., Brembeck F.H., Goehler H., Stroedicke M., Zenkner M., Schoenherr A., Koeppen S. et al.
Cell 122:957-968(2005) MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 MINT MINT-5004184 · UniProtKB (1) · Mapped (1,466)
MINT-63642. TM4SF1 (uniprotkb:P30408) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by two hybrid (MI:0018). From mint MINT MINT-5004184 MINT-63787. ARL4D (uniprotkb:P49703) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by two hybrid (MI:0018). From mint MINT MINT-5004184 MINT-64175. q14748_human (uniprotkb:Q14748) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by two hybrid (MI:0018). From mint MINT MINT-5004184 MINT-64855. TH1L (uniprotkb:Q8IXH7) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by two hybrid (MI:0018). From mint MINT MINT-5004184 MINT-65766. FZR1 (uniprotkb:Q9UM11) physically interacts (MI:0915) with DNAJA1 (uniprotkb:P31689) by two hybrid (MI:0018). From mint MINT MINT-5004184 |
