| The URA5 gene encoding orotate-phosphoribosyl transferase of the yeast Kluyveromyces lactis: cloning, sequencing and use as a selectable marker. Bai X., Larsen M., Meinhardt F.
Yeast 15:1393-1398(1999) SGD S000004573 · UniProtKB (2) · Mapped (2)
Fungal Related Genes/Proteins SGD S000004573 |
| Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae. Prinz W.A., Grzyb L., Veenhuis M., Kahana J.A., Silver P.A., Rapoport T.A.
J. Cell Biol. 150:461-474(2000) SGD S000004573 · Mapped (9)
Function/Process|Mutants/Phenotypes|Non-Fungal Related Genes/Proteins|Strains/Constructs SGD S000004573 |
| Nuclear export of yeast signal recognition particle lacking Srp54p by the Xpo1p/Crm1p NES-dependent pathway. Ciufo L.F., Brown J.D.
Curr. Biol. 10:1256-1264(2000) SGD S000004573 · Mapped (8)
Cellular Location|Function/Process|Protein Processing/Modification/Regulation|Techniques and Reagents SGD S000004573 |
| Sec63p and Kar2p are required for the translocation of SRP-dependent precursors into the yeast endoplasmic reticulum in vivo. Young B.P., Craven R.A., Reid P.J., Willer M., Stirling C.J.
EMBO J. 20:262-271(2001) SGD S000004573 · UniProtKB (1) · Mapped (5)
Function/Process|Genetic Interactions|Mutants/Phenotypes|Strains/Constructs SGD S000004573 |
| Biogenesis of the signal recognition particle (SRP) involves import of SRP proteins into the nucleolus, assembly with the SRP-RNA, and Xpo1p-mediated export. Grosshans H., Deinert K., Hurt E.C., Simos G.
J. Cell Biol. 153:745-762(2001) SGD S000004573 · UniProtKB (5) · Mapped (15)
Cellular Location SGD S000004573 |
| Gene order in a 10 275 bp fragment of Yarrowia lipolytica, including adjacent YlURA5 and YlSEC65 genes conserved in four yeast species. Sanchez M., Dominguez A.
Yeast 18:807-813(2001) SGD S000004573 · Mapped (4)
DNA/RNA Sequence Features|Fungal Related Genes/Proteins SGD S000004573 |
| An in vitro assay using overexpressed yeast SRP demonstrates that cotranslational translocation is dependent upon the J-domain of Sec63p. Willer M., Jermy A.J., Steel G.J., Garside H.J., Carter S., Stirling C.J.
Biochemistry 42:7171-7177(2003) SGD S000004573 · Mapped (7)
Function/Process|Mutants/Phenotypes|Strains/Constructs SGD S000004573 |
| Saccharomyces SRP RNA secondary structures: a conserved S-domain and extended Alu-domain. Van Nues R.W., Brown J.D.
RNA 10:75-89(2004) SGD S000004573 · Mapped (2)
Function/Process|Protein-Nucleic Acid Interactions SGD S000004573 |
| Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum. Stirling C.J., Rothblatt J., Hosobuchi M., Deshaies R., Schekman R.
Mol. Biol. Cell 3:129-142(1992) SGD S000004573 · UniProtKB (1) · Mapped (4)
Fungal Related Genes/Proteins|Mutants/Phenotypes SGD S000004573 |
| Transcriptome analysis of recombinant protein secretion by Aspergillus nidulans and the unfolded-protein response in vivo. Sims A.H., Gent M.E., Lanthaler K., Dunn-Coleman N.S., Oliver S.G., Robson G.D.
Appl. Environ. Microbiol. 71:2737-2747(2005) SGD S000004573 · Mapped (15)
Fungal Related Genes/Proteins SGD S000004573 |
| Signal recognition particles in chloroplasts, bacteria, yeast and mammals (review). Pool M.R.
Mol. Membr. Biol. 22:3-15(2005) SGD S000004573 · Mapped (7)
Reviews SGD S000004573 |
| Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Altmann K., Westermann B.
Mol. Biol. Cell 16:5410-5417(2005) SGD S000004573 · UniProtKB (1) · Mapped (78)
Function/Process|Mutants/Phenotypes|Strains/Constructs SGD S000004573 |
| Does a deficiency of the signal recognition particle (SRP)-pathway affect the biosynthesis of its components in Saccharomyces cerevisiae and Escherichia coli? Kovalskaya O.N., Sergiev P.V., Bogdanov A.A., Dontsova O.A.
Biochemistry Mosc. 71:723-729(2006) SGD S000004573 · Mapped (5)
Regulation of|Transcription SGD S000004573 |
| The methionine-rich domain of the 54 kd protein subunit of the signal recognition particle contains an RNA binding site and can be crosslinked to a signal sequence. Zopf D., Bernstein H.D., Johnson A.E., Walter P.
EMBO J. 9:4511-4517(1990) SGD S000004573 · UniProtKB (1) · Mapped (2)
Non-Fungal Related Genes/Proteins SGD S000004573 |
| Enhanced protein export in Saccharomyces cerevisiae nud1 mutants is an active process. Pesheva M.G., Koprinarova M.K., Venkov P.
Curr. Microbiol. 53:496-501(2006) SGD S000004573 · Mapped (6)
Genetic Interactions|Mutants/Phenotypes|Strains/Constructs SGD S000004573 |
| Membrane topology and post-translational modification of the Saccharomyces cerevisiae essential protein Rot1. Angeles Juanes M., Carlos Igual J., Carmen Bano M.
Yeast 25:93-106(2008) SGD S000004573 · UniProtKB (1) · Mapped (3)
Mutants/Phenotypes|Strains/Constructs SGD S000004573 |
| Novel cargo-binding site in the beta and delta subunits of coatomer. Michelsen K., Schmid V., Metz J., Heusser K., Liebel U., Schwede T., Spang A., Schwappach B.
J. Cell Biol. 179:209-217(2007) SGD S000004573 · Mapped (18)
Mutants/Phenotypes|Strains/Constructs SGD S000004573 |
| The protein secretory pathway of Candida albicans. Fonzi W.A.
Mycoses 0:0-0(2009) SGD S000004573 · Mapped (20)
S000004573 SGD S000004573 |
| Endoplasmic reticulum-associated secretory proteins Sec20p, Sec39p, and Dsl1p are involved in peroxisome biogenesis. Perry R.J., Mast F.D., Rachubinski R.A.
Eukaryotic Cell 8:830-843(2009) SGD S000004573 · Mapped (22)
Mutants/Phenotypes|Strains/Constructs SGD S000004573 |
| SRP samples nascent chains for the presence of signal sequences by interacting with ribosomes at a discrete step during translation elongation. Ogg S.C., Walter P.
Cell 81:1075-1084(1995) SGD S000004573 · Mapped (1)
Function/Process|Genetic Interactions|Mutants/Phenotypes SGD S000004573 |
| Retrograde lipid traffic in yeast: identification of two distinct pathways for internalization of fluorescent-labeled phosphatidylcholine from the plasma membrane. Kean L.S., Fuller R.S., Nichols J.W.
J. Cell Biol. 123:1403-1419(1993) SGD S000004573 · Mapped (15)
Function/Process|Fungal Related Genes/Proteins|Mutants/Phenotypes|Strains/Constructs|Techniques and Reagents SGD S000004573 |
| Folding and intracellular transport of the yeast plasma-membrane H(+)-ATPase: effects of mutations in KAR2 and SEC65. Chang A., Rose M.D., Slayman C.W.
Proc. Natl. Acad. Sci. U.S.A. 90:5808-5812(1993) SGD S000004573 · Mapped (2)
Function/Process|Mutants/Phenotypes|Techniques and Reagents SGD S000004573 |
| Interaction of rice and human SRP19 polypeptides with signal recognition particle RNA. Chittenden K., Gowda K., Black S.D., Zwieb C.
Plant Mol. Biol. 34:507-515(1997) SGD S000004573 · UniProtKB (1) · Mapped (1)
Non-Fungal Related Genes/Proteins SGD S000004573 |
| Isolation and cloning of the Yarrowia lipolytica SEC65 gene, a component of the yeast signal recognition particle displaying homology with the human SRP19 gene. Sanchez M., Beckerich J.-M., Gaillardin C., Dominguez A.
Gene 203:75-84(1997) SGD S000004573 · UniProtKB (1) · Mapped (1)
Function/Process|Fungal Related Genes/Proteins|Mutants/Phenotypes|Strains/Constructs SGD S000004573 |
| Folding of active beta-lactamase in the yeast cytoplasm before translocation into the endoplasmic reticulum. Paunola E., Suntio T., Jamsa E., Makarow M.
Mol. Biol. Cell 9:817-827(1998) SGD S000004573 · Mapped (6)
Function/Process|Mutants/Phenotypes|Strains/Constructs SGD S000004573 |
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