Delaguillaumie A., Lagaudriere-Gesbert C., Popoff M.R., Conjeaud H.

J. Cell. Sci. 115:433-443(2002) GeneRIF 3732 · Mapped (2)
An amplification loop via Vav and SLP76 phosphorylation and Rho-GTPase activation is initiated by CD82 association with the cytoskeleton thus permitting cytoskeletal rearrangement and costimulatory activity in T cells. GeneRIF 3732

Uzawa K., Ono K., Suzuki H., Tanaka C., Yakushiji T., Yamamoto N., Yokoe H., Tanzawa H.

Clin. Cancer Res. 8:828-835(2002) GeneRIF 3732 · Mapped (2)
Loss of KAII is associated with primary tumos with lymph node metastasis GeneRIF 3732

Iwata S., Kobayashi H., Miyake-Nishijima R., Sasaki T., Souta-Kuribara A., Nori M., Hosono O., Kawasaki H., Tanaka H., Morimoto C.

Eur. J. Immunol. 32:1328-1337(2002) GeneRIF 3732 · Mapped (2)
Evidence for distinctive signaling of CD82- and beta1 integrin-mediated costimulation at the transcriptional level of IL-2 gene. GeneRIF 3732

Jackson P., Grimm M.O., Kingsley E.A., Brosius U., Antalis T., Yardley G., Russell P.J.

Urol. Oncol. 7:99-104(2002) GeneRIF 3732 · Mapped (2)
relationship between expression mrna levels and p53 in human bladder and prostate cancer cell lines. GeneRIF 3732

Sauer G., Kurzeder C., Grundmann R., Kreienberg R., Zeillinger R., Deissler H.

Oncol. Rep. 10:405-410(2003) GeneRIF 3732 · Mapped (10)
downregulation of CD82 antigen is associated with breast tumor progression GeneRIF 3732

Jee B., Jin K., Hahn J.H., Song H.G., Lee H.

Exp. Mol. Med. 35:30-37(2003) GeneRIF 3732 · Mapped (2)
KAI1 induces homotypic aggregation of human prostatic neoplasm cells through Src-dependent pathway. GeneRIF 3732

Liu F.S., Dong J.T., Chen J.T., Hsieh Y.T., Ho E.S., Hung M.J., Lu C.H., Chiou L.C.

Clin. Cancer Res. 9:1393-1398(2003) GeneRIF 3732 · Mapped (4)
KAI1 expression is down-regulated in advanced endometrial cancer GeneRIF 3732

Zhang X.A., He B., Zhou B., Liu L.

J. Biol. Chem. 278:27319-27328(2003) GeneRIF 3732 · Mapped (21)
Requirement of the p130CAS-Crk coupling for metastasis suppressor KAI1/CD82-mediated inhibition of cell migration in a metastatic prostate cancer cell line. GeneRIF 3732

Ito Y., Yoshida H., Uruno T., Nakano K., Takamura Y., Miya A., Kobayashi K., Yokozawa T., Matsuzuka F., Kuma K. et al.

Pathol. Res. Pract. 199:79-83(2003) GeneRIF 3732 · Mapped (2)
KAI1 down-regulation is significantly related to the progression of papillary carcinoma including lymph node metastasis and its anaplastic transformation. GeneRIF 3732

Yang J., Liu F.X., Yan X.C., He G.Y., Liu L.M.

Ai Zheng 22:533-536(2003) GeneRIF 3732 · Mapped (2)
The abnormal expression of KAI1 participates in malignant progression of colorectal cancer. GeneRIF 3732

Wu Q., Ji Y., Zhang M.Q., Chen Y.Q., Chen F., Shi D.L., Zheng Z.H., Huang Y.J., Su W.J.

Cell Tissue Res. 314:237-249(2003) GeneRIF 3732 · Mapped (2)
KAI1 is a tumor metastasis suppressor gene in digestive tract carcinomas and cancer cells. GeneRIF 3732

Odintsova E., Voortman J., Gilbert E., Berditchevski F.

J. Cell. Sci. 116:4557-4566(2003) GeneRIF 3732 · Mapped (2)
CD82 regulates compartmentalisation of the EGF receptor GeneRIF 3732

Su J.S., Arima K., Hasegawa M., Franco O.E., Umeda Y., Yanagawa M., Sugimura Y., Kawamura J.

Int. J. Urol. 11:74-82(2004) GeneRIF 3732 · Mapped (4)
Decreased expression of KAI1 was associated with the degree of invasiveness and progression of the cancer and was an independent prognostic factor of recurrence in primary pTa and pT1 urothelial bladder carcinoma. GeneRIF 3732

Si S.H., Yang J.M., Peng Z.H., Luo Y.H., Zhou P.

World J. Gastroenterol. 10:2019-2023(2004) GeneRIF 3732 · Mapped (2)
Sense and antisense genes had no significant effects on cell growth and cell cycles. Sense KAI1 gene decreased invasive ability and decreased mitochondria. Clone formation and invasive ability increased after transfection with antisense KAI1 gene. GeneRIF 3732

Wu D.H., Liu L., Chen L.H., Ding Y.Q.

World J. Gastroenterol. 10:2245-2249(2004) GeneRIF 3732 · Mapped (2)
KAI1 is highly related to the metastasis of colonic carcinoma and may be a useful indicator of metastasis in colonic carcinoma. GeneRIF 3732

Chen Z., Mustafa T., Trojanowicz B., Brauckhoff M., Gimm O., Schmutzler C., Kohrle J., Holzhausen H.J., Kehlen A., Klonisch T. et al.

Int. J. Mol. Med. 14:517-527(2004) GeneRIF 3732 · Mapped (2)
CD82 may serve as a prognostic marker of metastasis in thyroid cancer GeneRIF 3732

Delaguillaumie A., Harriague J., Kohanna S., Bismuth G., Rubinstein E., Seigneuret M., Conjeaud H.

J. Cell. Sci. 117:5269-5282(2004) GeneRIF 3732 · Mapped (2)
CD82 controls the association of cholesterol-dependent microdomains with the actin cytoskeleton in T lymphocytes GeneRIF 3732

He B., Liu L., Cook G.A., Grgurevich S., Jennings L.K., Zhang X.A.

J. Biol. Chem. 280:3346-3354(2005) GeneRIF 3732 · Mapped (5)
CD82 attenuates integrin alpha6 signaling during a cellular morphogenic process GeneRIF 3732

Stark A.M., Tongers K., Maass N., Mehdorn H.M., Held-Feindt J.

J. Cancer Res. Clin. Oncol. 131:191-198(2005) GeneRIF 3732 · Mapped (17)
Our investigations revealed significantly reduced mRNA expression of metastases suppressor gene KAI1 in breast cancer brain metastasis. GeneRIF 3732

Bass R., Werner F., Odintsova E., Sugiura T., Berditchevski F., Ellis V.

J. Biol. Chem. 280:14811-14818(2005) GeneRIF 3732 · Mapped (5)
urokinase receptor proteolytic function is regulated by the tetraspanin CD82 GeneRIF 3732

Bai W.L., Ren Z., Pan Z.M., Gao H.

Zhonghua Zhong Liu Za Zhi 27:289-291(2005) GeneRIF 3732 · Mapped (2)
The decrease of KAI1 mRNA expression may be related to lymph node metastasis and lew differentiation of larynjeal squamous cell carcinoma. GeneRIF 3732

Mazurov D., Heidecker G., Derse D.

Virology 346:194-204(2006) GeneRIF 3732 · Mapped (2)
findings have shown that HTLV-1 Gag associates with CD82-enriched plasma membrane microdomains in Jurkat T cells GeneRIF 3732

Jee B.K., Park K.M., Surendran S., Lee W.K., Han C.W., Kim Y.S., Lim Y.

Biochem. Biophys. Res. Commun. 342:655-661(2006) GeneRIF 3732 · Mapped (2)
KAI1/CD82 over-expression in non-small cell lung carcinoma cells suppresses tumor invasiveness and metastatic potential by inducing matrix metalloproteinase-9 inactivation via up-regulation of tissue inhibitor of metalloproteinase-1 (TIMP-1). GeneRIF 3732

Shu Y., Chen H., Tan Y.

Lin Chuang Er Bi Yan Hou Ke Za Zhi 19:1065-1067(2005) GeneRIF 3732 · Mapped (2)
The expression of CD82 was closely correlated with lymph node metastasis in laryngeal carcinoma. GeneRIF 3732

Baek S.H.

Cell Cycle 5:1492-1495(2006) GeneRIF 3732 · Mapped (2)
REVIEW. The SUMOylation status of the reptin chromatin-remodeling complex modulates the KAI1 metastasis suppressor gene and the invasive activity of cancer cells with metastatic potential. GeneRIF 3732