Spizzo G., Gastl G., Wolf D., Gunsilius E., Steurer M., Fong D., Amberger A., Margreiter R., Obrist P.

Br. J. Cancer 88:574-578(2003) GeneRIF 4072 · Mapped (6)
Correlation of COX-2 and Ep-CAM overexpression in human invasive breast cancer and its impact on survival. GeneRIF 4072

Nasr A.F., Nutini M., Palombo B., Guerra E., Alberti S.

Oncogene 22:1668-1677(2003) GeneRIF 4072 · Mapped (34)
amplification is induced by mutations in TP53 GeneRIF 4072

Gires O., Eskofier S., Lang S., Zeidler R., Munz M.

Anticancer Res. 23:3255-3261(2003) GeneRIF 4072 · Mapped (1)
A 1100 bp fragment of the EpCAM promoter containing the 570 bp fragment and additional 550 bp upstream has been cloned GeneRIF 4072

Qu N., de Haan A., Harmsen M.C., Kroese F.G., de Leij L.F., Prop J.

Transplantation 76:1022-1028(2003) GeneRIF 4072 · Mapped (1)
Human EGP-2 antigen on epithelial cells of transgenic trachea transplants induces specific humoral and cellular immune responses leading to mild form of obliterative airway disease. (egp-2) GeneRIF 4072

Seligson D.B., Pantuck A.J., Liu X., Huang Y., Horvath S., Bui M.H., Han K.R., Correa A.J., Eeva M., Tze S. et al.

Clin. Cancer Res. 10:2659-2669(2004) GeneRIF 4072 · Mapped (1)
Epithelial cell adhesion molecule has a role in progression of renal cell carcinoma but is absent in clear cell carcinoma GeneRIF 4072

Varga M., Obrist P., Schneeberger S., Muhlmann G., Felgel-Farnholz C., Fong D., Zitt M., Brunhuber T., Schafer G., Gastl G. et al.

Clin. Cancer Res. 10:3131-3136(2004) GeneRIF 4072 · Mapped (1)
Ep-CAM antigen represents an attractive target for specific therapies with monoclonal antibodies or specific vaccines in patients with Ep-CAM-overexpressing gallbladder carcinoma. GeneRIF 4072

Heinzelmann-Schwarz V.A., Gardiner-Garden M., Henshall S.M., Scurry J., Scolyer R.A., Davies M.J., Heinzelmann M., Kalish L.H., Bali A., Kench J.G. et al.

Clin. Cancer Res. 10:4427-4436(2004) GeneRIF 4072 · Mapped (8)
up-regulation of DDR1 CLDN3 and epithelial cell adhesion molecule are early events in the development of epithelial ovarian cancer GeneRIF 4072

Mosolits S., Markovic K., Frodin J.E., Virving L., Magnusson C.G., Steinitz M., Fagerberg J., Mellstedt H.

Clin. Cancer Res. 10:5391-5402(2004) GeneRIF 4072 · Mapped (1)
Vaccination with Ep-CAM protein may warrant further investigation as a novel therapeutic approach to colorectal cancer. GeneRIF 4072

Krishnakumar S., Mohan A., Mallikarjuna K., Venkatesan N., Biswas J., Shanmugam M.P., Ren-Heidenreich L.

Invest. Ophthalmol. Vis. Sci. 45:4247-4250(2004) GeneRIF 4072 · Mapped (1)
EpCAM is vastly expressed in retinoblastoma; EpCAM reactivity was significantly higher in the invasive than the noninvasive tumors and in poorly differentiated than in well-differentiated tumors GeneRIF 4072

Xie X., Wang C.Y., Cao Y.X., Wang W., Zhuang R., Chen L.H., Dang N.N., Fang L., Jin B.Q.

World J. Gastroenterol. 11:344-347(2005) GeneRIF 4072 · Mapped (1)
Ep-CAM was distributed differently in normal and various malignant colon tissues. MAbs against Ep-CAM may have diagnostic and therapeutic value to various colon carcinomas. GeneRIF 4072

Rao C.G., Chianese D., Doyle G.V., Miller M.C., Russell T., Sanders R.A. Jr., Terstappen L.W.

Int. J. Oncol. 27:49-57(2005) GeneRIF 4072 · Mapped (1)
EpCAM expression in blood and primary and metastatic tumors is transient and dependent upon the local micro-environment GeneRIF 4072

Gommans W.M., van Eert S.J., McLaughlin P.M., Harmsen M.C., Yamamoto M., Curiel D.T., Haisma H.J., Rots M.G.

Cancer Gene Ther. 13:150-158(2006) GeneRIF 4072 · Mapped (1)
The carcinoma-specific epithelial glycoprotein-2 promoter controls efficient and selective gene expression in an adenoviral context. GeneRIF 4072

Hamada Y., Nakayama Y., Mizoguchi M., Ikeda S., Kuroki M., Iwasaki H.

Cancer Lett. 243:211-216(2006) GeneRIF 4072 · Mapped (1)
MK-1 expression was found in 61% of samples. GeneRIF 4072

Kimura H., Kato H., Faried A., Sohda M., Nakajima M., Fukai Y., Miyazaki T., Masuda N., Fukuchi M., Kuwano H.

Int. J. Oncol. 30:171-179(2007) GeneRIF 4072 · Mapped (1)
Tumor-specific EpCAM expression and release into the circulation may serve as effective immunotherapy in esophageal cancer patients. GeneRIF 4072

Gommans W.M., McLaughlin P.M., Lindhout B.I., Segal D.J., Wiegman D.J., Haisma H.J., van der Zaal B.J., Rots M.G.

Mol. Carcinog. 46:391-401(2007) GeneRIF 4072 · Mapped (1)
downregulation of EGP-2 promoter activity using zinc finger protein transcription factors may result in a novel anti-cancer treatment. GeneRIF 4072

Kuhn S., Koch M., Nubel T., Ladwein M., Antolovic D., Klingbeil P., Hildebrand D., Moldenhauer G., Langbein L., Franke W.W. et al.

Mol. Cancer Res. 5:553-567(2007) GeneRIF 4072 · Mapped (11)
claudin-7-associated EpCAM is recruited into (tetraspanin-enriched membrane microdomains) and forms a complex with CO-029 and CD44v6 that facilitates metastasis formation GeneRIF 4072

Schmelzer E., Reid L.M.

Front. Biosci. 13:3096-3100(2008) GeneRIF 4072 · Mapped (3)
analysis of EpCAM expression in normal non-pathological tissues GeneRIF 4072

Yamashita T., Budhu A., Forgues M., Wang X.W.

Cancer Res. 67:10831-10839(2007) GeneRIF 4072 · Mapped (11)
EpCAM is a Wnt-beta-catenin signaling target gene GeneRIF 4072

Trzpis M., Popa E.R., McLaughlin P.M., van Goor H., Timmer A., Bosman G.W., de Leij L.M., Harmsen M.C.

Nephron Exp. Nephrol. 107:e119-31(2007) GeneRIF 4072 · Mapped (4)
The spatiotemporal expression pattern of EpCAM changes during nephrogenesis GeneRIF 4072

Prince S., Zeidman A., Dekel Y., Ram E., Koren R.

Am. J. Clin. Pathol. 129:424-429(2008) GeneRIF 4072 · Mapped (1)
EpCAM expression in gallbladder tumors may serve as a prognostic factor for poor survival. GeneRIF 4072

Yamashita T., Forgues M., Wang W., Kim J.W., Ye Q., Jia H., Budhu A., Zanetti K.A., Chen Y., Qin L.X. et al.

Cancer Res. 68:1451-1461(2008) GeneRIF 4072 · Mapped (4)
EpCAM and alpha-fetoprotein are expressed in hepatocellular carcinoma GeneRIF 4072

van der Gun B.T., Wasserkort R., Monami A., Jeltsch A., Rasko T., Slaska-Kiss K., Cortese R., Rots M.G., de Leij L.F., Ruiters M.H. et al.

Int. J. Cancer 123:484-489(2008) GeneRIF 4072 · Mapped (1)
Active DNA methylation leads to sustained silencing of endogenous EpCAM expression. GeneRIF 4072

Bremer E., Helfrich W.

Front. Biosci. 13:5042-5049(2008) GeneRIF 4072 · Mapped (1)
Perspectives for EpCAM-targeted apoptosis induction in cancer by EpCAM-selective bispecific antibodies. [REVIEW} GeneRIF 4072

Anders M., Sarbia M., Grotzinger C., Meining A., Hofler H., Wiedenmann B., Rosch T.

Dis. Markers 24:287-292(2008) GeneRIF 4072 · Mapped (1)
Reduced expression of EpCAM and villin is associated withn Barrett's adenocarcinoma and expression of EpCam and villin differs only between squamous epithelium and Barrett esophagus GeneRIF 4072

Maaser K., Borlak J.

Br. J. Cancer 99:1635-1643(2008) GeneRIF 4072 · Mapped (3)
These data suggest that EpCAM is involved in signal transduction triggering several intracellular signalling pathways using tumor cell lines in colorectal and lung cancer. GeneRIF 4072