Sashiyama H., Shino Y., Sakao S., Shimada H., Kobayashi S., Ochiai T., Shirasawa H.

Cancer Lett. 177:21-28(2002) GeneRIF 3691 · Mapped (14)
Reduction in integrin alpha6beta4 is related to changes seen during immortalization and malignant progression GeneRIF 3691

Chettab K., Zibara K., Belaiba S.R., McGregor J.L.

Thromb. Haemost. 87:141-148(2002) GeneRIF 3691 · Mapped (23)
Acute hyperglycaemia induces an up-regulation of seven major genes four of which were not previously reported in the literature. Northern blot analyses performed on these 4 genes confirm macroarrays results for alphav beta4 c-myc and MUC18. GeneRIF 3691

Koster J., Kuikman I., Kreft M., Sonnenberg A.

J. Invest. Dermatol. 117:1405-1411(2001) GeneRIF 3691 · Mapped (7)
binding of beta 4 to plectin is essential for the proper formation and function of hemidesmosomes GeneRIF 3691

Micheloni A., Falcioni R., Zambruno G., D'Alessio M.

FEBS Lett. 519:238-239(2002) GeneRIF 3691 · Mapped (7)
The integrin beta4B and beta4C variants were found not to be expressed in a tissue-specific manner. GeneRIF 3691

Chung J., Bachelder R.E., Lipscomb E.A., Shaw L.M., Mercurio A.M.

J. Cell Biol. 158:165-174(2002) GeneRIF 3691 · Mapped (19)
Integrin (alpha 6 beta 4) regulation of eIF-4E activity and VEGF translation (Integrin alpha6beta4) GeneRIF 3691

Kitajiri S., Hosaka N., Hiraumi H., Hirose T., Ikehara S.

Pathol. Int. 52:438-441(2002) GeneRIF 3691 · Mapped (7)
integrin beta-4 expression in thyroid carcinoma may play a role in the development of gross lymph node metastasis of papillary carcinomas. GeneRIF 3691

Moretti R.M., Montagnani Marelli M., Motta M., Limonta P.

Oncol. Rep. 9:1139-1143(2002) GeneRIF 3691 · Mapped (19)
integrin beta4 expression is increased when ROR alpha is activated in prostate cancer cells GeneRIF 3691

Geuijen C.A., Sonnenberg A.

Mol. Biol. Cell 13:3845-3858(2002) GeneRIF 3691 · Mapped (10)
Data suggest that the stability of the interaction between alpha6beta4 and laminin-5 is influenced by the clustering of alpha6beta4 through the deposition of laminin-5 underneath the cells. GeneRIF 3691

Kim M.O., Yun S.J., Kim I.S., Sohn S., Lee E.H.

Neurosci. Lett. 336:93-96(2003) GeneRIF 3691 · Mapped (13)
Results suggest that alpha6beta4 integrin-mediated interactions of astrocytes with beta(ig)-h3 transduce intracellular signals through the focal adhesion proteins which may regulate certain aspects of astrocyte response to brain injury. GeneRIF 3691

Loducca S.V., Mantesso A., Kapas S., Williams D.M., Araujo N.S., Araujo V.C.

J. Oral Pathol. Med. 32:305-309(2003) GeneRIF 3691 · Mapped (12)
This study revealed detailed topography of integrins in malignant tumours derived from intercalated acinar segment of salivary gland which might be useful their diagnosis especially of fine-needle aspiration products or from incisional biopsy. GeneRIF 3691

Russell A.J., Fincher E.F., Millman L., Smith R., Vela V., Waterman E.A., Dey C.N., Guide S., Weaver V.M., Marinkovich M.P.

J. Cell. Sci. 116:3543-3556(2003) GeneRIF 3691 · Mapped (7)
extracellular domain of beta 4 integrin through its ability to bind ligand functions to integrate the divergent effects of growth factors on the cytoskeleton and adhesion receptors GeneRIF 3691

Santoro M.M., Gaudino G., Marchisio P.C.

Dev. Cell 5:257-271(2003) GeneRIF 3691 · Mapped (29)
Data show that macrophage stimulating protein (MSP) and its receptor (Ron) induce phosphorylation of both Ron and alpha6beta4 integrin and result in activation of alpha3beta1 integrin. GeneRIF 3691

Abdel-Ghany M., Cheng H.C., Elble R.C., Lin H., DiBiasio J., Pauli B.U.

J. Biol. Chem. 278:49406-49416(2003) GeneRIF 3691 · Mapped (7)
integrin beta4/calcium-activated chloride channel ligation elicits selective signaling via focal adhesion kinase to promote metastatic growth GeneRIF 3691

Gagnoux-Palacios L., Dans M., van't Hof W., Mariotti A., Pepe A., Meneguzzi G., Resh M.D., Giancotti F.G.

J. Cell Biol. 162:1189-1196(2003) GeneRIF 3691 · Mapped (10)
compartmentalization in lipid rafts is necessary to couple the alpha6beta4 integrin to a palmitoylated src family kinases and promote EGF-dependent mitogenesis. GeneRIF 3691

Yebra M., Montgomery A.M., Diaferia G.R., Kaido T., Silletti S., Perez B., Just M.L., Hildbrand S., Hurford R., Florkiewicz E. et al.

Dev. Cell 5:695-707(2003) GeneRIF 3691 · Mapped (16)
Data demonstrate that alpha6beta4 integrin mediates pancreatic epithelial cell adhesion to Netrin-1 whereas recruitment of alpha6beta4 and alpha3beta1 regulate the migration of putative pancreatic progenitors on Netrin-1. GeneRIF 3691

Masunaga T., Ishiko A., Takizawa Y., Kim S.C., Lee J.S., Nishikawa T., Shimizu H.

Exp. Dermatol. 13:61-64(2004) GeneRIF 3691 · Mapped (7)
Pyloric atresia-junctional epidermolysis bullosa syndrome is caused by mutations in this gene in a case report. GeneRIF 3691

Chung J., Yoon S.O., Lipscomb E.A., Mercurio A.M.

J. Biol. Chem. 279:32287-32293(2004) GeneRIF 3691 · Mapped (48)
alpha(6)beta(4) has a generic influence on the invasion of carcinoma cells that is not specific to Met GeneRIF 3691

Zhang L., Koivisto L., Heino J., Uitto V.J.

Biochem. Biophys. Res. Commun. 319:1088-1095(2004) GeneRIF 3691 · Mapped (10)
Results suggest that bacterial heat shock protein 60 may promote epithelial cell migration through activation of epidermal growth factor receptor and mitogen-activated protein kinases and inhibition of alpha6beta4 integrin expression. GeneRIF 3691

Enserink J.M., Price L.S., Methi T., Mahic M., Sonnenberg A., Bos J.L., Tasken K.

J. Biol. Chem. 279:44889-44896(2004) GeneRIF 3691 · Mapped (30)
cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the alpha3beta1 integrin but not the alpha6beta4 integrin GeneRIF 3691

Kippenberger S., Loitsch S., Muller J., Guschel M., Kaufmann R., Bernd A.

J. Invest. Dermatol. 123:444-451(2004) GeneRIF 3691 · Mapped (7)
link between the ligation of the beta(4) integrin and beta(1) integrin-mediated cell adhesion in carcinoma and pre-carcinoma cells. GeneRIF 3691

Oldak M., Smola H., Aumailley M., Rivero F., Pfister H., Smola-Hess S.

J. Virol. 78:10738-10746(2004) GeneRIF 3691 · Mapped (7)
high expression of HPV type 8 (HPV8) E2 in cultured primary keratinocytes leads to strong down-regulation of beta4-integrin expression levels GeneRIF 3691

Feng C., Ye C., Liu X., Ma H., Li M.

Biochem. Biophys. Res. Commun. 323:858-864(2004) GeneRIF 3691 · Mapped (7)
Blockage of beta4 integrin activity by antagonizing antibody abrogated ATV-induced endothelial death. GeneRIF 3691

Laferriere J., Houle F., Huot J.

Clin. Exp. Metastasis 21:257-264(2004) GeneRIF 3691 · Mapped (7)
activation by E-selectin thus modulating adhesion GeneRIF 3691

Hintermann E., Yang N., O'Sullivan D., Higgins J.M., Quaranta V.

J. Biol. Chem. 280:8004-8015(2005) GeneRIF 3691 · Mapped (22)
alpha6beta4 can augment cell-cell adhesion and slow down haptotaxis over laminin-5 GeneRIF 3691

Yang X., Kovalenko O.V., Tang W., Claas C., Stipp C.S., Hemler M.E.

J. Cell Biol. 167:1231-1240(2004) GeneRIF 3691 · Mapped (7)
The beta4 integrins is a functional connection between CD9 as evidenced by anti-CD9 antibody effects on beta4-dependent cell spreading. GeneRIF 3691