Ruano G., Bernene J., Windemuth A., Bower B., Wencker D., Seip R.L., Kocherla M., Holford T.R., Petit W.A., Hanks S.

Clin. Chim. Acta 400:48-55(2009) GAD 596434 GeneRIF 5916 · Mapped (563)
Not Associated with PHARMACOGENOMIC: BMI- Edema rosiglitazone or pioglitazone; GAD 596434 Observational study of gene-disease association gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator) GeneRIF 5916

Boudjelal M., Voorhees J.J., Fisher G.J.

Exp. Cell Res. 274:130-137(2002) GeneRIF 5916 · Mapped (13)
Retinoid signaling is attenuated by retinoic acid-induced proteasome-mediated degradation of RARG in human keratocytes. GeneRIF 5916

Pettersson F., Dalgleish A.G., Bissonnette R.P., Colston K.W.

Br. J. Cancer 87:555-561(2002) GeneRIF 5916 · Mapped (13)
Retinoids cause apoptosis in pancreatic cancer cells via activation of RAR-gamma and altered expression of Bcl-2/Bax. GeneRIF 5916

Klaholz B., Moras D.

Structure 10:1197-1204(2002) GeneRIF 5916 PDB 1FD0 · Mapped (6)
The 1.4 A resolution crystal structure of the ligand binding domain of the retinoic acid receptor RARgamma complexed with the retinoid SR11254 reveals several types of C-H...O hydrogen bonds GeneRIF 5916

Richter F., Joyce A., Fromowitz F., Wang S., Watson J., Watson R., Irwin R.J. Jr., Huang H.F.

J. Androl. 23:830-838(2002) GeneRIF 5916 · Mapped (17)
Present throughout the epithelium with minimal nuclear accumulation. Increased in basal and luminal epithelial nuclei in glands with benign prostatic hyperplasia. GeneRIF 5916

Hauksdottir H., Farboud B., Privalsky M.L.

Mol. Endocrinol. 17:373-385(2003) GeneRIF 5916 · UniProtKB (2) · Mapped (20)
RARgamma interact only weakly with SMRT. GeneRIF 5916

Farboud B., Hauksdottir H., Wu Y., Privalsky M.L.

Mol. Cell. Biol. 23:2844-2858(2003) GeneRIF 5916 · Mapped (17)
RAR beta and RAR gamma receptors appear to adopt a constitutively closed helix 12 conformation in the absence of hormone that may approximate the conformation of RAR alpha when bound to hormone agonist. GeneRIF 5916

Pinaire J., Chou W.Y., Morton M., You M., Zeng Y., Cho W.K., Galli A., Everett L., Breen H., Dumaual N. et al.

Alcohol. Clin. Exp. Res. 27:1860-1866(2003) GeneRIF 5916 · Mapped (22)
In a 9-cis retinoic acid-dependent fashion in cells in vitro retinoic acid receptor isoform gamma stimulates the expression of reporter constructs containing the site that binds aldehyde dehydrogenase-2. GeneRIF 5916

Andersson E., Rosdahl I., Torma H., Vahlquist A.

Exp. Dermatol. 12:563-571(2003) GeneRIF 5916 · Mapped (13)
depletion of vitamin A and retinoid receptors by UV irradiation together with unchanged or even increased c-Jun levels might seriously interfere with retinoid signaling and thus promote future tumor development especially in keratinocytes. GeneRIF 5916

Yen A., Fenning R., Chandraratna R., Walker P., Varvayanis S.

Mol. Pharmacol. 66:1727-1737(2004) GeneRIF 5916 · Mapped (17)
Tazarotene is a prodrug selective for RARbeta/gamma thereby motivating interest in determining whether tazarotene might activate putative tumor suppressor activity. GeneRIF 5916

Feng J., Chen J., Yan J., Jones I.R., Craddock N., Cook E.H. Jr., Goldman D., Heston L.L., Sommer S.S.

Am. J. Med. Genet. B Neuropsychiatr. Genet. 133B:50-53(2005) GeneRIF 5916 GAD 133621 · Mapped (53)
Not Associated with PSYCH: schizophrenia; autism; alcoholism; bipolar disorder; attention deficit hyperactivity disorder; GAD 133621 Observational study of gene-disease association. (HuGE Navigator) GeneRIF 5916

Bour G., Plassat J.L., Bauer A., Lalevee S., Rochette-Egly C.

J. Biol. Chem. 280:17027-17037(2005) GeneRIF 5916 · Mapped (14)
phosphorylation of the AF-1 domain controls RARgamma-mediated transcription through triggering the dissociation of vinexin beta GeneRIF 5916

Marinelli A., Bossi D., Pelicci P.G., Minucci S.

Leukemia 21:647-650(2007) GeneRIF 5916 · Mapped (17)
Biological properties of the other RAR isoforms (RARbeta and RARgamma) through the generation pf fusion protein isoforms in acutte promyelocytic leukemia. GeneRIF 5916

Dey N., De P.K., Wang M., Zhang H., Dobrota E.A., Robertson K.A., Durden D.L.

Mol. Cell. Biol. 27:4179-4197(2007) GeneRIF 5916 · Mapped (16)
study elucidated a nongenomic extranuclear signal mediated by the RAR-SRC interaction that is negatively regulated by CSK and is required for RA-induced neuronal differentiation GeneRIF 5916

Marinelli A., Bossi D., Pelicci P.G., Minucci S.

Leukemia 23:417-419(2009) GeneRIF 5916 · Mapped (6)
analysis to determine directly whether PML-RAR like PML-RAR is able to induce APL GeneRIF 5916

Makkonen K.M., Pasonen-Seppanen S., Torronen K., Tammi M.I., Carlberg C.

J. Biol. Chem. 284:18270-18281(2009) GeneRIF 5916 · Mapped (17)
The first 2250 bp of the HAS2 promoter contain three response elements (REs) for the transcription factor CREB1 as well as two REs for the nuclear receptor RAR GeneRIF 5916

Han Y.H., Zhou H., Kim J.H., Yan T.D., Lee K.H., Wu H., Lin F., Lu N., Liu J., Zeng J.Z. et al.

J. Biol. Chem. 284:18503-18514(2009) GeneRIF 5916 · Mapped (6)
the subcellular localization of RARgamma is regulated by complex interactions among ligand binding receptor phosphorylation and receptor dimerizations GeneRIF 5916

Hua S., Kittler R., White K.P.

Cell 137:1259-1271(2009) GeneRIF 5916 · Mapped (64)
Study found that RARalpha/RARgamma exhibit extensive colocalization of their genomic binding regions with ERalpha in the vicinity of genes that are antagonistically regulated by estrogen and RA. GeneRIF 5916

Gurevich I., Aneskievich B.J.

Biochem. Biophys. Res. Commun. 389:409-414(2009) GeneRIF 5916 · Mapped (23)
TNIP1 interacts with liganded RARalpha and RARgamma but acts as a corepressor of their activity. GeneRIF 5916

Ovsyannikova I.G., Dhiman N., Haralambieva I.H., Vierkant R.A., O'Byrne M.M., Jacobson R.M., Poland G.A.

Hum. Genet. 127:207-221(2010) GeneRIF 5916 · Mapped (69)
Data show significant associations between SNPs in RARA RARB TOP2B and RARG RXRA TLR3 TRIM5 and RIG-I genes and rubella virus-specific cytokine immune responses; Observational study of gene-disease association. (HuGE Navigator) GeneRIF 5916

BRIGHT Consortium
Talmud P.J., Drenos F., Shah S., Shah T., Palmen J., Verzilli C., Gaunt T.R., Pallas J., Lovering R., Li K. et al.

Am. J. Hum. Genet. 85:628-642(2009) GeneRIF 5916 · Mapped (10,092)
Observational study of gene-disease association. (HuGE Navigator) GeneRIF 5916

Roberts K.E., Kawut S.M., Krowka M.J., Brown R.S. Jr., Trotter J.F., Shah V., Peter I., Tighiouart H., Mitra N., Handorf E. et al.

Gastroenterology 139:130-9.e24(2010) GeneRIF 5916 · Mapped (491)
Observational study of gene-disease association. (HuGE Navigator) GeneRIF 5916

Bairras C., Redonnet A., Dabadie H., Gin H., Atgie C., Pallet V., Higueret P., Noel-Suberville C.

J. Physiol. Biochem. 66:29-37(2010) GeneRIF 5916 · Mapped (6)
PARgamma expressions are decreased in PBMC and SWAT of obese subjects in weight gain. GeneRIF 5916

Koszewski N.J., Herberth J., Malluche H.H.

J. Steroid Biochem. Mol. Biol. 120:200-207(2010) GeneRIF 5916 · Mapped (6)
Retinoic acid receptor gamma 2 could specifically interact with vitamin D response elements either in the presence or absence of the vitamin D receptor. GeneRIF 5916

Bailey S.D., Xie C., Do R., Montpetit A., Diaz R., Mohan V., Keavney B., Yusuf S., Gerstein H.C., Engert J.C. et al.

Diabetes Care 33:2250-2253(2010) GeneRIF 5916 · Mapped (10,071)
Observational study of gene-disease association gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator) GeneRIF 5916