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1 - 25 of 155 results for uniprot:P08648 in Computationally mapped citations

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An alternative processing of integrin alpha(v) subunit in tumor cells by membrane type-1 matrix metalloproteinase.

Ratnikov B.I., Rozanov D.V., Postnova T.I., Baciu P.G., Zhang H., DiScipio R.G., Chestukhina G.G., Smith J.W., Deryugina E.I., Strongin A.Y.

J. Biol. Chem. 277:7377-7385(2002) GeneRIF 3678 · Mapped (4)
alternative pathway of pro-alpha(v) processing involving MT1-MMP: regulation of integrin functionality may be an important role of MT1-MMP in migrating tumor cells. GeneRIF 3678

The PDZ domain of TIP-2/GIPC interacts with the C-terminus of the integrin alpha5 and alpha6 subunits.

El Mourabit H., Poinat P., Koster J., Sondermann H., Wixler V., Wegener E., Laplantine E., Geerts D., Georges-Labouesse E., Sonnenberg A. et al.

Matrix Biol. 21:207-214(2002) GeneRIF 3678 · Mapped (9)
The PDZ domain of TIP-2/GIPC interacts with the C-terminus of the integrin alpha5 and alpha6 subunits. GeneRIF 3678

Increased binding and defective migration across fibronectin of cycling hematopoietic progenitor cells.

Giet O., Van Bockstaele D.R., Di Stefano I., Huygen S., Greimers R., Beguin Y., Gothot A.

Blood 99:2023-2031(2002) GeneRIF 3678 · Mapped (14)
role in mediating adhesion and migration of activated cycling CD34+ hematopoietic progenitor cells onto fibronectin GeneRIF 3678

Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain.

Mould A.P., Askari J.A., Barton S., Kline A.D., McEwan P.A., Craig S.E., Humphries M.J.

J. Biol. Chem. 277:19800-19805(2002) GeneRIF 3678 · Mapped (4)
Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain GeneRIF 3678

Antiphospholid antibodies regulate the expression of trophoblast cell adhesion molecules.

Di Simone N., Castellani R., Caliandro D., Caruso A.

Fertil. Steril. 77:805-811(2002) GeneRIF 3678 · Mapped (12)
results suggest that the inadequate trophoblastic invasion induced by antiphospholipid antibodies can be the result of decreased alpha1 integrin and VE-cadherin and increased alpha5 integrin and E-cadherin expression in the trophoblast GeneRIF 3678

Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies.

Francis S.E., Goh K.L., Hodivala-Dilke K., Bader B.L., Stark M., Davidson D., Hynes R.O.

Arterioscler. Thromb. Vasc. Biol. 22:927-933(2002) GeneRIF 3678 · Mapped (4)
Central role of alpha5beta1 integrin in vascular development in mouse embryos and embryoid bodies. GeneRIF 3678

TGF-beta1-stimulated osteoblasts require intracellular calcium signaling for enhanced alpha5 integrin expression.

Nesti L.J., Caterson E.J., Wang M., Chang R., Chapovsky F., Hoek J.B., Tuan R.S.

Ann. N. Y. Acad. Sci. 961:178-182(2002) GeneRIF 3678 · Mapped (13)
TGF-beta1-stimulated osteoblasts require intracellular calcium signaling for enhanced alpha5 integrin expression GeneRIF 3678

The alpha5beta1 integrin provides matrix survival signals for normal and osteoarthritic human articular chondrocytes in vitro.

Pulai J.I., Del Carlo M. Jr., Loeser R.F.

Arthritis Rheum. 46:1528-1535(2002) GeneRIF 3678 · Mapped (4)
The alpha5beta1 integrin provides matrix survival signals for normal and osteoarthritic human articular chondrocytes in vitro. GeneRIF 3678

Alpha 5 beta 1 integrin activates an NF-kappa B-dependent program of gene expression important for angiogenesis and inflammation.

Klein S., de Fougerolles A.R., Blaikie P., Khan L., Pepe A., Green C.D., Koteliansky V., Giancotti F.G.

Mol. Cell. Biol. 22:5912-5922(2002) GeneRIF 3678 · Mapped (4)
results suggest that engagement of the alpha 5 beta 1 integrin promotes an NF-kappa B-dependent program of gene expression that coordinately regulates angiogenesis and inflammation GeneRIF 3678

Expression of focal adhesion kinase and alpha5 and beta1 integrins in carcinomas and its clinical significance.

Su J.M., Gui L., Zhou Y.P., Zha X.L.

World J. Gastroenterol. 8:613-618(2002) GeneRIF 3678 · Mapped (13)
Expression of focal adhesion kinase and alpha5 and beta1 integrins in carcinomas and its clinical significance. GeneRIF 3678

Bordetella pertussis infection of human respiratory epithelial cells up-regulates intercellular adhesion molecule-1 expression: role of filamentous hemagglutinin and pertussis toxin.

Ishibashi Y., Nishikawa A.

Microb. Pathog. 33:115-125(2002) GeneRIF 3678 · Mapped (13)
B. pertussis FHA up-regulates ICAM-1 expression on respiratory epithelial cells through interaction of its RGD site with host cell VLA-5 integrin and that PT impairs this response GeneRIF 3678

Endostatin associates with integrin alpha5beta1 and caveolin-1, and activates Src via a tyrosyl phosphatase-dependent pathway in human endothelial cells.

Wickstrom S.A., Alitalo K., Keski-Oja J.

Cancer Res. 62:5580-5589(2002) GeneRIF 3678 · Mapped (10)
Elevated expression of IL-8 (and not PTHrP) by MDA-MET cells is a phenotypic change that may be related to their enhanced ability to metastasize to the skeleton. GeneRIF 3678

The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis.

Danen E.H., Sonneveld P., Brakebusch C., Fassler R., Sonnenberg A.

J. Cell Biol. 159:1071-1086(2002) GeneRIF 3678 · Mapped (27)
integrin alpha5beta1 extracellular domain controls rhoA activity GeneRIF 3678

CTGF mediates TGF-beta-induced fibronectin matrix deposition by upregulating active alpha5beta1 integrin in human mesangial cells.

Weston B.S., Wahab N.A., Mason R.M.

J. Am. Soc. Nephrol. 14:601-610(2003) GeneRIF 3678 · Mapped (10)
Alterations in alpha5beta1 levels induced by TGF-beta are mediated at least in part through the induction of CTGF in glomerular mesangium GeneRIF 3678

Thymidine phosphorylase and 2-deoxyribose stimulate human endothelial cell migration by specific activation of the integrins alpha 5 beta 1 and alpha V beta 3.

Hotchkiss K.A., Ashton A.W., Schwartz E.L.

J. Biol. Chem. 278:19272-19279(2003) GeneRIF 3678 · Mapped (18)
thymidine phosphorylase and 2-deoxyribose-induced focal adhesion kinase phosphorylation was blocked by the antibodies to integrins alpha 5 beta 1 and alpha v beta 3 directly linking their migration and signaling components GeneRIF 3678

Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins.

Sudhakar A., Sugimoto H., Yang C., Lively J., Zeisberg M., Kalluri R.

Proc. Natl. Acad. Sci. U.S.A. 100:4766-4771(2003) GeneRIF 3678 · UniProtKB (1) · Mapped (13)
endostatin competes with fibronectin/RGD cyclic peptide to bind alpha 5 beta 1 integrin GeneRIF 3678

Identification of a novel binding site for platelet integrins alpha IIb beta 3 (GPIIbIIIa) and alpha 5 beta 1 in the gamma C-domain of fibrinogen.

Podolnikova N.P., Yakubenko V.P., Volkov G.L., Plow E.F., Ugarova T.P.

J. Biol. Chem. 278:32251-32258(2003) GeneRIF 3678 · Mapped (15)
identification of binding site in gamma C-domain of fibrinogen GeneRIF 3678

Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins.

Bax D.V., Bernard S.E., Lomas A., Morgan A., Humphries J., Shuttleworth C.A., Humphries M.J., Kielty C.M.

J. Biol. Chem. 278:34605-34616(2003) GeneRIF 3678 · Mapped (19)
alpha 5 beta 1 and alpha v beta 3 are both important but cell-specific fibrillin-1 receptors GeneRIF 3678

Vascular endothelial growth factor receptor-1 is deposited in the extracellular matrix by endothelial cells and is a ligand for the alpha 5 beta 1 integrin.

Orecchia A., Lacal P.M., Schietroma C., Morea V., Zambruno G., Failla C.M.

J. Cell. Sci. 116:3479-3489(2003) GeneRIF 3678 · Mapped (13)
VEGFR-1 secreted by endothelial cells interacts with the alpha 5 beta 1 integrin GeneRIF 3678

Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis.

Mould A.P., Symonds E.J., Buckley P.A., Grossmann J.G., McEwan P.A., Barton S.J., Askari J.A., Craig S.E., Bella J., Humphries M.J.

J. Biol. Chem. 278:39993-39999(2003) GeneRIF 3678 · Mapped (4)
visualized the head region of integrin alpha 5 beta 1 in an inactive (Ca2+-occupied) state and in complex with a fragment of fibronectin containing the RGD and synergy recognition sequences GeneRIF 3678

Structure of integrin alpha5beta1 in complex with fibronectin.

Takagi J., Strokovich K., Springer T.A., Walz T.

EMBO J. 22:4607-4615(2003) GeneRIF 3678 · Mapped (4)
The structural conformation of this protein complexed wigh integrin beta1 complexed with fibronectin is examined. GeneRIF 3678

The homeobox transcription factor Hox D3 promotes integrin alpha5beta1 expression and function during angiogenesis.

Boudreau N.J., Varner J.A.

J. Biol. Chem. 279:4862-4868(2004) GeneRIF 3678 · Mapped (5)
Hox D3 coordinately regulates the expression of integrin alpha5beta1 and integrin alphavbeta3 during angiogenesis in vivo. GeneRIF 3678

Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells.

Bax D.V., Messent A.J., Tart J., van Hoang M., Kott J., Maciewicz R.A., Humphries M.J.

J. Biol. Chem. 279:22377-22386(2004) GeneRIF 3678 · Mapped (19)
Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells GeneRIF 3678

Introduction of bisecting GlcNAc into integrin alpha5beta1 reduces ligand binding and down-regulates cell adhesion and cell migration.

Isaji T., Gu J., Nishiuchi R., Zhao Y., Takahashi M., Miyoshi E., Honke K., Sekiguchi K., Taniguchi N.

J. Biol. Chem. 279:19747-19754(2004) GeneRIF 3678 · Mapped (18)
beta1 4-N-acetylglucosaminyltransferase III inhibits the function of alpha5beta1 integrin GeneRIF 3678

Functional differences between integrin alpha4 and integrins alpha5/alphav in modulating the motility of human oral squamous carcinoma cells in response to the V region and heparin-binding domain of fibronectin.

Zhang Y., Lu H., Dazin P., Kapila Y.

Exp. Cell Res. 295:48-58(2004) GeneRIF 3678 · Mapped (14)
Role of alpha4 alpha5 and alphav integrin receptors--which are central to mediating interactions with these domains of FN--in regulating ssquamous cell carcinoma migration. GeneRIF 3678

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