Volkman B.F., Prehoda K.E., Scott J.A., Peterson F.C., Lim W.A.

Cell 111:565-576(2002) GeneRIF 7456 MINT MINT-238480 MINT MINT-238480 · UniProtKB (1) · Mapped (8)
MINT-15948. WASIP (uniprotkb:O43516) binds (MI:0407) to WASL (uniprotkb:O08816) by filter binding (MI:0049). From mint MINT MINT-238480 MINT-15949. WASIP (uniprotkb:O43516) and WASL (uniprotkb:O08816) bind (MI:0407) by x-ray crystallography (MI:0114). From mint MINT MINT-238480 show that the N-WASP EVH1 domain specifically binds a 25 residue motif from the WASP Interacting Protein (WIP) GeneRIF 7456

Luthi J.N., Gandhi M.J., Drachman J.G.

Exp. Hematol. 31:150-158(2003) GeneRIF 7456 · Mapped (6)
X-linked thrombocytopenia caused by a mutation in the WAS gene that disrupts interaction with the (WASP)-interacting protein (WIP). GeneRIF 7456

Kim M.K., Kim E.S., Kim D.S., Choi I.H., Moon T., Yoon C.N., Shin J.S.

Biochim. Biophys. Acta 1690:134-140(2004) GeneRIF 7456 · Mapped (6)
interactions of WASP and WIP are affected by two novel mutations that change the conformation of WASP and disrupt hydrogen bonding GeneRIF 7456

Rajmohan R., Meng L., Yu S., Thanabalu T.

Biochem. Biophys. Res. Commun. 342:529-536(2006) GeneRIF 7456 · Mapped (8)
Only in the presence of WASP-interacting protein (WIP) can human WASP suppress the growth defect of Saccharomyces cerevisiae las17Delta strain. GeneRIF 7456

Krzewski K., Chen X., Orange J.S., Strominger J.L.

J. Cell Biol. 173:121-132(2006) GeneRIF 7456 · Mapped (5)
A 1.3 mD multiprotein complex consisting of WASp-interacting protein (WIP) Wiskott-Aldrich syndrome protein (WASp) actin and myosin IIA formigg during NK cell activation was identified with a role in complex formation and NK cell activity regulation. GeneRIF 7456

de la Fuente M.A., Sasahara Y., Calamito M., Anton I.M., Elkhal A., Gallego M.D., Suresh K., Siminovitch K., Ochs H.D., Anderson K.C. et al.

Proc. Natl. Acad. Sci. U.S.A. 104:926-931(2007) GeneRIF 7456 · Mapped (12)
WASP-interacting protein stabilizes Wiskott-Aldrich syndrome protein(WASP) and suggest that it may also be important for its function GeneRIF 7456

Dong X., Patino-Lopez G., Candotti F., Shaw S.

J. Biol. Chem. 282:30303-30310(2007) GeneRIF 7456 · Mapped (12)
the WIP-WASP complex plays an important role in WASP stabilization and NFAT activation GeneRIF 7456

Tsuboi S., Meerloo J.

J. Biol. Chem. 282:34194-34203(2007) GeneRIF 7456 · Mapped (9)
that WASP and WASP-interacting protein (WIP) form a complex at the phagocytic cup and that the WASP.WIP complex plays a critical role in the phagocytic cup formation. GeneRIF 7456

Anton I.M., Jones G.E., Wandosell F., Geha R., Ramesh N.

Trends Cell Biol. 17:555-562(2007) GeneRIF 7456 · Mapped (5)
In this review in addition to its WASP-independent functions the role of WIP is to regulate the activity and stability of WASP and shuttle WASP to areas of actin assembly. GeneRIF 7456

Krzewski K., Chen X., Strominger J.L.

Proc. Natl. Acad. Sci. U.S.A. 105:2568-2573(2008) GeneRIF 7456 · Mapped (5)
WIP is involved in lytic granule transport and is essential for regulation of Natural killer cell cytotoxic function GeneRIF 7456

Tsuboi S., Takada H., Hara T., Mochizuki N., Funyu T., Saitoh H., Terayama Y., Yamaya K., Ohyama C., Nonoyama S. et al.

J. Biol. Chem. 284:8548-8556(2009) GeneRIF 7456 · Mapped (22)
formin-binding protein 17 (FBP17) recruits WASP WASP-interacting protein (WIP) and dynamin-2 to the plasma membrane and that this recruitment is necessary for the formation of podosomes and phagocytic cups. GeneRIF 7456

Staub E., Groene J., Heinze M., Mennerich D., Roepcke S., Klaman I., Hinzmann B., Castanos-Velez E., Pilarsky C., Mann B. et al.

J. Mol. Med. 87:633-644(2009) GeneRIF 7456 · Mapped (5)
Groups of colorectal cancer breast cancer and glioma patients with low expression of the WIPF1 co-expression module generally had a favorable prognosis. GeneRIF 7456

Rajmohan R., Raodah A., Wong M.H., Thanabalu T.

FEMS Yeast Res. 9:1226-1235(2009) GeneRIF 7456 · Mapped (7)
The results suggest that some of the mutations in the WH1 domain cause the Wiskott-Aldrich syndrome syndrome in humans by perturbing the WASP-WIP complex formation. GeneRIF 7456

Franco A., Knafo S., Banon-Rodriguez I., Merino-Serrais P., Fernaud-Espinosa I., Nieto M., Garrido J.J., Esteban J.A., Wandosell F., Anton I.M.

Cereb. Cortex 22:1191-1202(2012) GeneRIF 7456 · Mapped (5)
These findings reveal WIP as a previously unreported regulator of neuronal maturation and synaptic activity GeneRIF 7456

Ingham R.J., Colwill K., Howard C., Dettwiler S., Lim C.S., Yu J., Hersi K., Raaijmakers J., Gish G., Mbamalu G. et al.

Mol. Cell. Biol. 25:7092-7106(2005) MINT MINT-238480 · Mapped (62)
MINT-73064. WBP4 (uniprotkb:O75554) physically interacts (MI:0915) with WIPF1 (uniprotkb:O43516) by pull down (MI:0096). From mint MINT MINT-238480

Tsuboi S., Nonoyama S., Ochs H.D.

EMBO Rep. 7:506-511(2006) MINT MINT-238480 · Mapped (16)
MINT-2748661. WASL (uniprotkb:O00401) physically interacts (MI:0915) with WIPF1 (uniprotkb:O43516) by anti bait coimmunoprecipitation (MI:0006). From mint MINT MINT-238480

Wu C., Ma M.H., Brown K.R., Geisler M., Li L., Tzeng E., Jia C.Y., Jurisica I., Li S.S.

Proteomics 7:1775-1785(2007) MINT MINT-238480 · Mapped (204)
MINT-7246954. WIPF1 (uniprotkb:O43516) binds (MI:0407) to FYN (uniprotkb:P06241) by peptide array (MI:0081). From mint MINT MINT-238480