| Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan. The I., Bellaiche Y., Perrimon N.
Mol. Cell 4:633-639(1999) FlyBase FBgn0029175 · UniProtKB (1) · Mapped (16) |
| Specificities of heparan sulphate proteoglycans in developmental processes. Perrimon N., Bernfield M.
Nature 404:725-728(2000) FlyBase FBgn0029175 · Mapped (17) |
| Demonstration of a novel gene DEXT3 of Drosophila melanogaster as the essential N-acetylglucosamine transferase in the heparan sulfate biosynthesis: chain initiation and elongation. Kim B.-T., Kitagawa H., Tamura J., Kusche-Gullberg M., Lindahl U., Sugahara K.
J. Biol. Chem. 277:13659-13665(2002) FlyBase FBgn0029175 · UniProtKB (1) · Mapped (3) |
| Glycosylation of proteins in plants and invertebrates. Wilson I.B.
Curr. Opin. Struct. Biol. 12:569-577(2002) FlyBase FBgn0029175 · Mapped (40) |
| Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells. Lum L., Yao S., Mozer B., Rovescalli A., Von Kessler D., Nirenberg M., Beachy P.A.
Science 299:2039-2045(2003) FlyBase FBgn0029175 · UniProtKB (1) · Mapped (84) |
| Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans. Takei Y., Ozawa Y., Sato M., Watanabe A., Tabata T.
Development 131:73-82(2004) FlyBase FBgn0029175 · UniProtKB (3) · Mapped (16) |
| Morphogens, their identification and regulation. Tabata T., Takei Y.
Development 131:703-712(2004) FlyBase FBgn0029175 · Mapped (59) |
| Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation. Han C., Belenkaya T.Y., Khodoun M., Tauchi M., Lin X., Lin X.
Development 131:1563-1575(2004) FlyBase FBgn0029175 GeneRIF 3772101 · UniProtKB (3) · Mapped (9)
Results suggest that all three Drosophila EXT proteins -- tout-velu brother of tout-velu and sister of tout-velu -- are required for the biosynthesis of heparan sulfate proteoglycans and for the gradient formation of morphogens. GeneRIF 3772101 |
| Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways. Bornemann D.J., Duncan J.E., Staatz W., Selleck S., Warrior R.
Development 131:1927-1938(2004) FlyBase FBgn0029175 · UniProtKB (3) · Mapped (14) |
| Genome-wide transcription profile of field- and laboratory-selected dichlorodiphenyltrichloroethane (DDT)-resistant Drosophila. Pedra J.H., McIntyre L.M., Scharf M.E., Pittendrigh B.R.
Proc. Natl. Acad. Sci. U.S.A. 101:7034-7039(2004) FlyBase FBgn0029175 · Mapped (176) |
| Shifted, the Drosophila ortholog of wnt inhibitory factor-1, controls the distribution and movement of hedgehog. Glise B., Miller C.A., Crozatier M., Halbisen M.A., Wise S., Olson D.J., Vincent A., Blair S.S.
Dev. Cell 8:255-266(2005) FlyBase FBgn0029175 · UniProtKB (1) · Mapped (24) |
| Mechanisms of Hedgehog gradient formation and interpretation. Torroja C., Gorfinkiel N., Guerrero I.
J. Neurobiol. 64:334-356(2005) FlyBase FBgn0029175 · Mapped (72) |
| Heparan sulfate polymerization in Drosophila. Izumikawa T., Egusa N., Taniguchi F., Sugahara K., Kitagawa H.
J. Biol. Chem. 281:1929-1934(2006) FlyBase FBgn0029175 · UniProtKB (1) · Mapped (3) |
| The ihog cell-surface proteins bind Hedgehog and mediate pathway activation. Yao S., Lum L., Beachy P.A.
Cell 125:343-357(2006) FlyBase FBgn0029175 · UniProtKB (1) · Mapped (24) |
| Functional conservation of the human EXT1 tumor suppressor gene and its Drosophila homolog tout velu. Dasgupta U., Dixit B.L., Rusch M., Selleck S., The I.
Dev. Genes Evol. 217:555-561(2007) FlyBase FBgn0029175 · Mapped (4) |
| Functional analysis of proteoglycan galactosyltransferase II RNA interference mutant flies. Ueyama M., Takemae H., Ohmae Y., Yoshida H., Toyoda H., Ueda R., Nishihara S.
J. Biol. Chem. 283:6076-6084(2008) FlyBase FBgn0029175 · Mapped (19) |
| A translational block to HSPG synthesis permits BMP signaling in the early Drosophila embryo. Bornemann D.J., Park S., Phin S., Warrior R.
Development 135:1039-1047(2008) FlyBase FBgn0029175 · Mapped (22) |
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