uniprot:A4D1G0 in citationmapping

1 - 25 of 41 results for uniprot:A4D1G0 in citationmapping

Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer. Ovarian Cancer Association Consortium Cancer Res. 67:3027-3035(2007) GAD 145316 GeneRIF 1021 · Mapped (58) Not Associated with CANCER: ovarian cancer; GAD 145316 Observational study of gene-disease association. (HuGE Navigator) GeneRIF 1021
CAK-independent activation of CDK6 by a viral cyclin. Kaldis P., Ojala P.M., Tong L., Makela T.P., Solomon M.J. Mol. Biol. Cell 12:3987-3999(2001) GeneRIF 1021 · Mapped (2) KSHV-cyclin can activate CDK6 independent of phosphorylation by CAK in vitro GeneRIF 1021
Structural basis for CDK6 activation by a virus-encoded cyclin. Schulze-Gahmen U., Kim S.H. Nat. Struct. Biol. 9:177-181(2002) GeneRIF 1021 · Mapped (4) crystal structure of human CDK6--Vcyclin in an active state was determined to 3.1 A resolution to better understand the structural basis of CDK6 activation by viral cyclins GeneRIF 1021
Translocation t(2;7)(p12;q21-22) with dysregulation of the CDK6 gene mapping to 7q21-22 in a non-Hodgkin's lymphoma with leukemia. Brito-Babapulle V., Gruszka-Westwood A.M., Platt G., Andersen C.L., Elnenaei M.O., Matutes E., Wotherspoon A.C., Weston-Smith S.G., Catovsky D. Haematologica 87:357-362(2002) GeneRIF 1021 · Mapped (2) a patient with the dignosis of B-cell lymphoma with cdk6 expression is dysregulated mapping to chromosome 7. GeneRIF 1021
Sequential extension of proliferative lifespan in human fibroblasts induced by over-expression of CDK4 or 6 and loss of p53 function. Morris M., Hepburn P., Wynford-Thomas D. Oncogene 21:4277-4288(2002) GeneRIF 1021 · Mapped (39) Sequential extension of proliferative lifespan in human fibroblasts is induced by over-expression of CDK4 or 6 and loss of p53 function. GeneRIF 1021
Overexpression of Cdk6-cyclin D3 highly sensitizes cells to physical and chemical transformation. Chen Q., Lin J., Jinno S., Okayama H. Oncogene 22:992-1001(2003) GeneRIF 1021 · Mapped (5) Overexpression of transfected human Cdk6 & mouse cyclin D3 enhances susceptibility of BALB/c3T3 & C3H10T1/2 mouse fibroblast lines to UV radiation & 3-methylcholanthrene transformation. GeneRIF 1021
End-stage differentiation of neutrophil granulocytes in vivo is accompanied by up-regulation of p27kip1 and down-regulation of CDK2, CDK4, and CDK6. Klausen P., Bjerregaard M.D., Borregaard N., Cowland J.B. J. Leukoc. Biol. 75:569-578(2004) GeneRIF 1021 · Mapped (19) cyclin-dependent kinase (CDK)2 -4 and -6 were down-regulated from the myelocytes/metamyelocytes stages and onward GeneRIF 1021
Cyclin-dependent kinase 6 inhibits proliferation of human mammary epithelial cells. Lucas J.J., Domenico J., Gelfand E.W. Mol. Cancer Res. 2:105-114(2004) GeneRIF 1021 · Mapped (2) cdk6 restrains rather than stimulates breast epithelial cell proliferation and that its loss or down-regulation could play a role in breast tumor development GeneRIF 1021
In human immature BFU-E tumor necrosis factor-alpha not only downregulates CDK6 but also directly produces apoptosis which is prevented by stem cell factor. Dai C., Chung I.J., Krantz S.B. Exp. Hematol. 32:911-917(2004) GeneRIF 1021 · Mapped (9) the amount of CDK6 was reduced by TNF-alpha while CDK6 and the FLICE-inhibitory protein (FLIP) were increased with SCF GeneRIF 1021
Positive and negative regulation of c-Myb by cyclin D1, cyclin-dependent kinases, and p27 Kip1. Lei W., Liu F., Ness S.A. Blood 105:3855-3861(2005) GeneRIF 1021 · Mapped (24) c-Myb activity is directly regulated by cyclin D1 and CDKs and imply that c-Myb activity is regulated during the cell cycle in hematopoietic cells GeneRIF 1021
Cyclin-dependent kinase 6 associates with the androgen receptor and enhances its transcriptional activity in prostate cancer cells. Lim J.T., Mansukhani M., Weinstein I.B. Proc. Natl. Acad. Sci. U.S.A. 102:5156-5161(2005) GeneRIF 1021 · Mapped (10) CDK6 may play an important role in the development and/or progression of a subset of human prostate cancers by stimulating the activity of the AR. GeneRIF 1021
Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma. Mendrzyk F., Radlwimmer B., Joos S., Kokocinski F., Benner A., Stange D.E., Neben K., Fiegler H., Carter N.P., Reifenberger G. et al. J. Clin. Oncol. 23:8853-8862(2005) GeneRIF 1021 · Mapped (8) Overexpression of CDK6 correlated significantly with poor prognosis and represented an independent prognostic marker of overall survival in medulloblastoma. GeneRIF 1021
CDK4 and CDK6 delay senescence by kinase-dependent and p16INK4a-independent mechanisms. Ruas M., Gregory F., Jones R., Poolman R., Starborg M., Rowe J., Brookes S., Peters G. Mol. Cell. Biol. 27:4273-4282(2007) GeneRIF 1021 · Mapped (15) CDK6 delays senescence by kinase-dependent and p16INK4a-independent mechanisms. GeneRIF 1021
Association study of 69 genes in the ret pathway identifies low-penetrance loci in sporadic medullary thyroid carcinoma. Ruiz-Llorente S., Montero-Conde C., Milne R.L., Moya C.M., Cebrian A., Leton R., Cascon A., Mercadillo F., Landa I., Borrego S. et al. Cancer Res. 67:9561-9567(2007) GeneRIF 1021 · Mapped (32) Observational study of gene-disease association. (HuGE Navigator) GeneRIF 1021
Amplification at 7q22 targets cyclin-dependent kinase 6 in T-cell lymphoma. Nagel S., Leich E., Quentmeier H., Meyer C., Kaufmann M., Drexler H.G., Zettl A., Rosenwald A., MacLeod R.A. Leukemia 22:387-392(2008) GeneRIF 1021 · Mapped (2) Amplification of the CDK6 locus was analyzed in primary T-cell lymphoma samples and while detected infrequently in those classified as ALCL (1%) was detected in 23% of peripheral T-cell lymphomas not otherwise specified. GeneRIF 1021
Cyclin-dependent kinase phosphorylation of RUNX1/AML1 on 3 sites increases transactivation potency and stimulates cell proliferation. Zhang L., Fried F.B., Guo H., Friedman A.D. Blood 111:1193-1200(2008) GeneRIF 1021 · Mapped (9) cdk phosphorylation of RUNX1 potentially couples stem/progenitor proliferation and lineage progression GeneRIF 1021
Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population. Driver K.E., Song H., Lesueur F., Ahmed S., Barbosa-Morais N.L., Tyrer J.P., Ponder B.A., Easton D.F., Pharoah P.D., Dunning A.M. Carcinogenesis 29:333-341(2008) GeneRIF 1021 · Mapped (58) Observational study of gene-disease association. (HuGE Navigator) GeneRIF 1021
Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival. Song H., Hogdall E., Ramus S.J., Dicioccio R.A., Hogdall C., Quaye L., McGuire V., Whittemore A.S., Shah M., Greenberg D. et al. Clin. Cancer Res. 14:1090-1095(2008) GeneRIF 1021 · Mapped (70) Observational study of gene-disease association. (HuGE Navigator) GeneRIF 1021
TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression. Ayala Y.M., Misteli T., Baralle F.E. Proc. Natl. Acad. Sci. U.S.A. 105:3785-3789(2008) GeneRIF 1021 · Mapped (30) Cdk6 up-regulation in TDP-43-depleted cells is accompanied by an increase in phosphorylation of two of its major targets the retinoblastoma protein pRb and pRb-related protein pRb2/p130. GeneRIF 1021
Genetic variants in cell cycle control pathway confer susceptibility to bladder cancer. Ye Y., Yang H., Grossman H.B., Dinney C., Wu X., Gu J. Cancer 112:2467-2474(2008) GeneRIF 1021 · Mapped (62) Observational study of gene-disease association. (HuGE Navigator) GeneRIF 1021
Genome-wide association analysis identifies 20 loci that influence adult height. Wellcome Trust Case Control Consortium Nat. Genet. 40:575-583(2008) GeneRIF 1021 · Mapped (45) Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) GeneRIF 1021
Genome-wide linkage scan for atypical nevi in p16-Leiden melanoma families. de Snoo F.A., Hottenga J.J., Gillanders E.M., Sandkuijl L.A., Jones M.P., Bergman W., van der Drift C., van Leeuwen I., van Mourik L., Huurne J.A. et al. Eur. J. Hum. Genet. 16:1135-1141(2008) GeneRIF 1021 · Mapped (9) An atypical nevus susceptibility gene has been mapped to chromosome band 7q21.3 containing CDK6. GeneRIF 1021
Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest. Sun F., Fu H., Liu Q., Tie Y., Zhu J., Xing R., Sun Z., Zheng X. FEBS Lett. 582:1564-1568(2008) GeneRIF 1021 · Mapped (8) miR-34a reduces both mRNA and protein levels of cyclin D1 (CCND1) and cyclin-dependent kinase 6 (CDK6). GeneRIF 1021
Molecular dissection of the chromosome band 7q21 amplicon in gastroesophageal junction adenocarcinomas identifies cyclin-dependent kinase 6 at both genomic and protein expression levels. van Dekken H., van Marion R., Vissers K.J., Hop W.C., Dinjens W.N., Tilanus H.W., Wink J.C., van Duin M. Genes Chromosomes Cancer 47:649-656(2008) GeneRIF 1021 · Mapped (2) high-resolution genomic analysis and immunoprofiling identify CDK6 as the main candidate target for the recurrent amplification of 7q21 in GEJ adenocarcinomas GeneRIF 1021
Amplification studies of MET and Cdk6 in a rat endometrial tumor model and their correlation to human type I endometrial carcinoma tumors. Samuelson E., Nordlander C., Levan G., Behboudi A. Adv. Exp. Med. Biol. 617:511-517(2008) GeneRIF 1021 · Mapped (25) Amplification of CDK6 is associated with type I endometrial carcinoma tumors GeneRIF 1021