uniprot:A4D0Q6 in citationmapping

1 - 25 of 160 results for uniprot:A4D0Q6 in citationmapping

Phosphatidylinositol 3-kinase controls human intestinal epithelial cell differentiation by promoting adherens junction assembly and p38 MAPK activation. Laprise P., Chailler P., Houde M., Beaulieu J.F., Boucher M.J., Rivard N. J. Biol. Chem. 277:8226-8234(2002) GeneRIF 5294 · Mapped (9) PI3K promotes assembly of adherens junctions which in turn control p38 MAPK activation and enterocyte differentiation. GeneRIF 5294
TEL/platelet-derived growth factor receptor beta activates phosphatidylinositol 3 (PI3) kinase and requires PI3 kinase to regulate the cell cycle. Dierov J., Xu Q., Dierova R., Carroll M. Blood 99:1758-1765(2002) GeneRIF 5294 · Mapped (12) activates phosphatidylinositol 3 (PI3) kinase and requires PI3 kinase to regulate the cell cycle [TEL/platelet-derived growth factor receptor beta] GeneRIF 5294
Recruitment of phosphatidylinositol 3-kinase to CD28 inhibits HIV transcription by a Tat-dependent mechanism. Cook J.A., August A., Henderson A.J. J. Immunol. 169:254-260(2002) GeneRIF 5294 · Mapped (7) PI3K inhibits HIV-1 transcription by targeting the viral protein Tat activation complex. GeneRIF 5294
v-Crk activates the phosphoinositide 3-kinase/AKT pathway by utilizing focal adhesion kinase and H-Ras. Akagi T., Murata K., Shishido T., Hanafusa H. Mol. Cell. Biol. 22:7015-7023(2002) GeneRIF 5294 · Mapped (4) data indicated that the v-Crk-induced activation of PI3K/AKT pathway was cooperatively achieved by two distinct interactions GeneRIF 5294
Mechanism of extracellular signal-regulated kinase activation by the CB(1) cannabinoid receptor. Galve-Roperh I., Rueda D., Gomez del Pulgar T., Velasco G., Guzman M. Mol. Pharmacol. 62:1385-1392(2002) GeneRIF 5294 · Mapped (7) CB(1)-induced ERK activation was mediated by PI3K(IB) and this effect may have important consequences in the control of cell death/survival decision. GeneRIF 5294
Role of phosphatidylinositol 3-kinase in the binding of Bordetella pertussis to human monocytes. Ishibashi Y., Yoshimura K., Nishikawa A., Claus S., Laudanna C., Relman D.A. Cell. Microbiol. 4:825-833(2002) GeneRIF 5294 · Mapped (4) Bordetella pertussis infection of human monocytes resulted in a marked recruitment of cellular PI3-K to the sites of B. pertussis contact GeneRIF 5294
Down-regulation of PIK3CG, a catalytic subunit of phosphatidylinositol 3-OH kinase, by CpG hypermethylation in human colorectal carcinoma. Semba S., Itoh N., Ito M., Youssef E.M., Harada M., Moriya T., Kimura W., Yamakawa M. Clin. Cancer Res. 8:3824-3831(2002) GeneRIF 5294 · Mapped (4) Down-regulation of PIK3CG by CpG hypermethylation is associated with progression of colorectal cancer GeneRIF 5294
Decreased phosphorylation of protein kinase B and extracellular signal-regulated kinase in neutrophils from patients with myelodysplasia. Fuhler G.M., Drayer A.L., Vellenga E. Blood 101:1172-1180(2003) GeneRIF 5294 · Mapped (16) higher protein levels of the PI3K subunit p110 in neutrophils from MDS patients GeneRIF 5294
Downregulation of uPA inhibits migration and PI3k/Akt signaling in glioblastoma cells. Chandrasekar N., Mohanam S., Gujrati M., Olivero W.C., Dinh D.H., Rao J.S. Oncogene 22:392-400(2003) GeneRIF 5294 · Mapped (12) These results indicate that PI3k/Akt pathway is involved in the signaling cascade of glioma cells required to induce cell migration. GeneRIF 5294
Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages. Francois F., Klotman M.E. J. Virol. 77:2539-2549(2003) GeneRIF 5294 · Mapped (4) regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages GeneRIF 5294
Purinergic P2Y12 receptor blockade inhibits shear-induced platelet phosphatidylinositol 3-kinase activation. Resendiz J.C., Feng S., Ji G., Francis K.A., Berndt M.C., Kroll M.H. Mol. Pharmacol. 63:639-645(2003) GeneRIF 5294 · Mapped (8) PI3-K activation is signaled by rapid feedback amplification that involves P2Y(12) receptor-mediated activation of Syk. GeneRIF 5294
Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis. Joy A.M., Beaudry C.E., Tran N.L., Ponce F.A., Holz D.R., Demuth T., Berens M.E. J. Cell. Sci. 116:4409-4417(2003) GeneRIF 5294 · Mapped (4) migrating glioma cells activate the PI3-K survival pathway protecting migrating cells from apoptosis GeneRIF 5294
Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45. Osaki M., Kase S., Adachi K., Takeda A., Hashimoto K., Ito H. J. Cancer Res. Clin. Oncol. 130:8-14(2004) GeneRIF 5294 · Mapped (4) 1) the PI3K-Akt pathway plays an important role in preventing Fas-mediated apoptosis; and 2) a PI3 K inhibitor such as LY294002 might be a useful anti-tumoral agent for gastric carcinoma GeneRIF 5294
Prolongation of insulin-induced activation of mitogen-activated protein kinases ERK 1/2 and phosphatidylinositol 3-kinase by vanadyl sulfate, a protein tyrosine phosphatase inhibitor. Theberge J.F., Mehdi M.Z., Pandey S.K., Srivastava A.K. Arch. Biochem. Biophys. 420:9-17(2003) GeneRIF 5294 · Mapped (17) Vanadyl sulfate treatment also prolonged the insulin-stimulated activation of phosphatidylinositol 3-kinase (PI3-K). GeneRIF 5294
Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells. Andreozzi F., D'Alessandris C., Federici M., Laratta E., Del Guerra S., Del Prato S., Marchetti P., Lauro R., Perticone F., Sesti G. Endocrinology 145:2845-2857(2004) GeneRIF 5294 · Mapped (15) Activation of hexosamine pathway affects glucose-induced phosphorylation of IRS-1. Impairs coupling of IRS-1 and PI 3-kinase and activativates Akt/mammalian target of rapamycin/phosphorylated heat- and acid-stable protein-1/p70S6 kinase pathway. GeneRIF 5294
The IL-1 receptor accessory protein is essential for PI 3-kinase recruitment and activation. Reddy S.A., Lin Y.F., Huang H.J., Samanta A.K., Liao W.S. Biochem. Biophys. Res. Commun. 316:1022-1028(2004) GeneRIF 5294 · Mapped (7) Thus our results identified a functional region in the IL-1R AcP required for the recruitment and activation of PI 3-kinase. GeneRIF 5294
Phosphoinositide 3-kinase gamma: kinase-dependent and -independent activities in cardiovascular function and disease. Alloatti G., Montrucchio G., Lembo G., Hirsch E. Biochem. Soc. Trans. 32:383-386(2004) GeneRIF 5294 · Mapped (12) PI3Kgamma appears to negatively control cardiac contractility through different signalling mechanisms [review] GeneRIF 5294
Alpha-lipoic acid mitigates insulin resistance in Goto-Kakizaki rats. Bitar M.S., Wahid S., Pilcher C.W., Al-Saleh E., Al-Mulla F. Horm. Metab. Res. 36:542-549(2004) GeneRIF 5294 · Mapped (11) In Goto-Kakizaki rat soleus muscle chronic administration of antioxidant alpha -lipoic-acid partly ameliorated the diabetes-related deficit in glucose metabolism including the enzymes Akt/PKB and PI-3 kinase. GeneRIF 5294
Inhibition of PI3K, mTOR and MEK signaling pathways promotes rapid apoptosis in B-lineage ALL in the presence of stromal cell support. Bertrand F.E., Spengemen J.D., Shelton J.G., McCubrey J.A. Leukemia 19:98-102(2005) GeneRIF 5294 · Mapped (12) stromal cell-mediated apoptotic protection in B-lineage ALL is mediated by PI3K/mTOR and MEK via a synergistic mechanism GeneRIF 5294
Frequent genetic and biochemical alterations of the PI 3-K/AKT/PTEN pathway in head and neck squamous cell carcinoma. Pedrero J.M., Carracedo D.G., Pinto C.M., Zapatero A.H., Rodrigo J.P., Nieto C.S., Gonzalez M.V. Int. J. Cancer 114:242-248(2005) GeneRIF 5294 · Mapped (7) PI 3-kinase-initiated signaling pathway is one of the most frequently altered in head and neck squamous cell carcinoma. GeneRIF 5294
Amiloride augments TRAIL-induced apoptotic death by inhibiting phosphorylation of kinases and phosphatases associated with the P13K-Akt pathway. Kim K.M., Lee Y.J. Oncogene 24:355-366(2005) GeneRIF 5294 · Mapped (7) Amiloride enhances TRAIL-induced cytotoxicity by inhibiting phosphorylation of the PI 3-Kinase-Akt pathway-associated kinases and phosphatases. GeneRIF 5294
Association analysis between longevity in the Japanese population and polymorphic variants of genes involved in insulin and insulin-like growth factor 1 signaling pathways. Kojima T., Kamei H., Aizu T., Arai Y., Takayama M., Nakazawa S., Ebihara Y., Inagaki H., Masui Y., Gondo Y. et al. Exp. Gerontol. 39:1595-1598(2004) GeneRIF 5294 · Mapped (22) Observational study of gene-disease association. (HuGE Navigator) GeneRIF 5294
Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase gamma. Voigt P., Brock C., Nurnberg B., Schaefer M. J. Biol. Chem. 280:5121-5127(2005) GeneRIF 5294 · UniProtKB (1) · Mapped (6) there is a previously unknown p101-related regulatory subunit for PI3Kgamma GeneRIF 5294
A phosphatidyl-inositol-3-kinase-dependent anti-inflammatory pathway activated by Salmonella in epithelial cells. Huang F.C., Li Q., Cherayil B.J. FEMS Microbiol. Lett. 243:265-270(2005) GeneRIF 5294 · Mapped (11) activation of the PI3K/Akt pathway identified as an anti-inflammatory signal that may contribute to the establishment of Salmonella typhimurium in the intestine. GeneRIF 5294
Requirement for NF-(kappa)B in interleukin-4-induced androgen receptor activation in prostate cancer cells. Lee S.O., Lou W., Nadiminty N., Lin X., Gao A.C. Prostate 64:160-167(2005) GeneRIF 5294 · Mapped (13) IL-4 > PI3K/Akt > NF-(kappa)B signaling pathways which activate androgen receptor signaling play an important role during the development of androgen independent prostate cancer cells. GeneRIF 5294