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The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.


  • Forthcoming changes
    Planned changes for UniProt

  • UniProt release 2016_04
    Small changes, big effects | New UniProt JAPI | Change of the UniProt RDF files distribution

  • UniProt release 2016_03
    From the Zika forest to the Amazon, news from a viral wanderer | Cross-references to EPD and TopDownProteomics

  • UniProt release 2016_02
    Another one (antibiotic) bites the dust | Cross-references to SwissPalm and Gramene | Removal of cross-references to GeneFarm and GenoLi...

  • UniProt release 2016_01
    cGAMP, a welcome stowaway | Cross-references to CollecTF, GeneDB and iPTMnet

News archive

Getting started

  • Text search
    Our basic text search allows you to search all the resources available

    Find regions of similarity between your sequences

  • Sequence alignments
    Align two or more protein sequences using the Clustal Omega program

  • Retrieve/ID mapping
    This tool merges the "Retrieve" and "ID Mapping" tools

UniProt data

Protein spotlight

a tighter mesh

A fabric whose weave is slack is less resistant to strain than one whose knit is close. These physical principles of toughness are followed by Nature all the way down the molecular scale. At the cellular level, protrusions known as microvilli grow at the apical end of the epithelial cells that line the intestinal tract. Each protrusion is like a finger dipping into the gut lumen…