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The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.

Getting started

  • Text search
    Our basic text search allows you to search all the resources available

    Find regions of similarity between your sequences

  • Sequence alignments
    Align two or more protein sequences using the Clustal Omega program

  • Retrieve/ID mapping
    Batch search with UniProt IDs or convert them to another type of database ID (or vice versa)

  • Peptide search
    Find sequences that exactly match a query peptide sequence

UniProt data

Protein spotlight

it's a thin line

One cell. One organism. One fate: male, or female. The way Nature designs things, you would expect traits as fundamental as those that make a boy a boy or a girl a girl, for instance, to be inscribed in their respective DNA from the very start. In a way they are, of course, but there is a subtlety: if what defines gender is for some reason missing, then the other sex may emerge almost by default…