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The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.


  • Forthcoming changes
    There are currently no changes planned

  • UniProt release 2017_09
    Protein translation goes round in circles | Cross-references to CORUM

  • UniProt release 2017_08
    Curation of human immunoglobulin genes: a fruitful collaboration between UniProtKB/Swiss-Prot and IMGT | Cross-references to ELM

  • UniProt release 2017_07
    A pseudogene turns into an active DNA methyltransferase dedicated to male fertility

  • UniProt release 2017_06
    Eukaryotic sex: good ideas shared with viruses | Change of cross-references to PATRIC | New file listing deleted and subsequently reinst...

News archive

Getting started

  • Text search
    Our basic text search allows you to search all the resources available

    Find regions of similarity between your sequences

  • Sequence alignments
    Align two or more protein sequences using the Clustal Omega program

  • Retrieve/ID mapping
    This tool merges the "Retrieve" and "ID Mapping" tools

  • Peptide search
    Find sequences that exactly match a query peptide sequence

UniProt data

Protein spotlight

a touch of warmth

We need heat. All warm-blooded animals know this instinctively because when life leaves us, the cold creeps in fast. Heat is produced in different ways inside us, and not only to keep our body temperature at a healthy level but also to keep it stable. After the fashion of small mobile furnaces, we carry adipose tissues that are full of stored fat waiting to be burnt down to release heat - a process termed thermogenesis…