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The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.


  • Forthcoming changes
    Planned changes for UniProt

  • UniProt release 2017_01
    Sheep in wolves' clothing | Change of the UniRef FASTA header

  • UniProt release 2016_11
    From mouth to gut, a new mechanism for fimbriae assembly | Change of URIs for Ensembl and Ensembl Genomes

  • UniProt release 2016_10
    N-acyl amino acids: a new treatment for obesity? | Cross-references to DisGeNET and OpenTargets | Change of the cross-references to Phos...

  • UniProt release 2016_09
    Ki-67: the great leap from simple marker to functional actor | Change of RDF representation of the cross-references to family and domain...

News archive

Getting started

  • Text search
    Our basic text search allows you to search all the resources available

    Find regions of similarity between your sequences

  • Sequence alignments
    Align two or more protein sequences using the Clustal Omega program

  • Retrieve/ID mapping
    This tool merges the "Retrieve" and "ID Mapping" tools

  • Peptide search
    Find sequences that exactly match a query peptide sequence

UniProt data

Protein spotlight

the contours of heredity

Life has its shapes, and depends on all kinds of architecture. It needs a skeleton on which to hang. Blood vessels in which to flow. A brain to house its thoughts. A heart to give it a beat. On a far smaller scale, it needs cells to accommodate all the various components without which there would be no life in the first place. One of the most important being: DNA. DNA itself is found within a defined structure in each of our cells: the nucleus…