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The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.


  • A never-ending race between evolution and genomic integrity | Cross-references to BioMuta
    UniProt release 2015_05

  • Of CAT tails and protein translation by-products | Reducing redundancy in proteomes | Retirement of UniProt Metagenomic and Environmenta...
    UniProt release 2015_04

  • Regulation of translation initiation through folding | New proteomics mapping files | New FTP repository for reference proteomes | UniPa...
    UniProt release 2015_03

  • Mosquitoes prefer human
    UniProt release 2015_02

News archive

Getting started

  • Text search
    Our basic text search allows you to search all the resources available

    Find regions of similarity between your sequences

  • Sequence alignments
    Align two or more protein sequences using the Clustal Omega program

  • Retrieve/ID mapping
    This tool merges the "Retrieve" and "ID Mapping" tools

UniProt data

Protein spotlight

a question of perspective

Paradigms are meant to be broken. In the 1980s, biology students were taught "the one gene = one protein" dogma which has since stepped down from its pedestal, as we now know that one gene, by way of any number of post-translational modifications on the protein sequence, can actually give rise to more than one protein. Or what would be more correct: to more than one function…