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The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.


  • Forthcoming changes
    Planned changes for UniProt

  • UniProt release 2017_08
    Curation of human immunoglobulin genes: a fruitful collaboration between UniProtKB/Swiss-Prot and IMGT | Cross-references to ELM

  • UniProt release 2017_07
    A pseudogene turns into an active DNA methyltransferase dedicated to male fertility

  • UniProt release 2017_06
    Eukaryotic sex: good ideas shared with viruses | Change of cross-references to PATRIC | New file listing deleted and subsequently reinst...

  • UniProt release 2017_05
    A certain taste for light | Extension of controlled vocabulary for PTM to glycosylation sites | Addition of GO annotation to UniRef90 an...

News archive

Getting started

  • Text search
    Our basic text search allows you to search all the resources available

    Find regions of similarity between your sequences

  • Sequence alignments
    Align two or more protein sequences using the Clustal Omega program

  • Retrieve/ID mapping
    This tool merges the "Retrieve" and "ID Mapping" tools

  • Peptide search
    Find sequences that exactly match a query peptide sequence

UniProt data

Protein spotlight

a taste of light

Light gave life a chance to be. Without it, our planet would not be inhabited by so many living beings of all shapes and sizes. Over time, animals, plants and all sorts of microorganisms have emerged and evolved using this source of photons in different ways. Like hosts of other creatures, we use light for vision so that we can discern individual entities that make up our environment, as well as movement within it…