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The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.


  • Forthcoming changes
    Planned changes for UniProt

  • UniProt release 2016_01
    cGAMP, a welcome stowaway | Cross-references to CollecTF, GeneDB and iPTMnet

  • UniProt release 2015_12
    Host proteins SERINC3 and SERINC5 decrease HIV-1 infectivity | Displaying human UniProtKB sequence annotations in genome browser tracks ...

  • UniProt release 2015_11
    The sense of a motion | Change of the cross-references to eggNOG

  • UniProt release 2015_10
    The smell of the sea in UniProtKB | Cross-references to WBParaSite | Removal of the cross-references to CYGD | UniParc cross-reference t...

News archive

Getting started

  • Text search
    Our basic text search allows you to search all the resources available

    Find regions of similarity between your sequences

  • Sequence alignments
    Align two or more protein sequences using the Clustal Omega program

  • Retrieve/ID mapping
    This tool merges the "Retrieve" and "ID Mapping" tools

UniProt data

Protein spotlight

shaping life

We take our shape for granted. As we do the contours of our eyes and the curves of our heart. But for everything to be sculpted the way Nature has found it best for us to be, cells need to know when to multiply and when to stop multiplying, in addition to knowing how to remain close to one another while dealing with external forces such as the gravitational pull. It all comes down to a very delicate balance between biology and physics…