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The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.


  • Forthcoming changes
    Planned changes for UniProt

  • UniProt release 2015_08
    Pseudo-allergy, real progress | Programmatic access to UniProt with | Addition of human variants from COSMIC on the U...

  • UniProt release 2015_07
    Coding-non-coding RNAs: a game of hide-and-seek | Cross-references to ESTHER and Genevisible | Removal of the cross-references to Geneve...

  • UniProt release 2015_06
    POLQ, a new target for cancer therapy?

  • UniProt release 2015_05
    A never-ending race between evolution and genomic integrity | Removal of IPI species proteome data sets from FTP site | UniProtKB XSD ch...

News archive

Getting started

  • Text search
    Our basic text search allows you to search all the resources available

    Find regions of similarity between your sequences

  • Sequence alignments
    Align two or more protein sequences using the Clustal Omega program

  • Retrieve/ID mapping
    This tool merges the "Retrieve" and "ID Mapping" tools

UniProt data

Protein spotlight

becoming two

Long before complex life arose, bacteria had mastered the art of living. To survive, these single-celled organisms learned how to divide, with one cell giving rise to two, then two to four, and so on. It was a survival strategy that turned out to be so convenient that it was adopted, and has evolved over billions of years. Decades of research have been put into understanding bacterial division…